End-condition for solution small angle X-ray scattering measurements by kernel density estimation
We develop a method for calculating the minimum X-ray exposure time for X-ray solution scattering experiments using statistical and mathematical approaches to enhance the measurement efficiency while maintaining data quality. Experts can determine the X-ray exposure time for samples by investigating...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Taylor & Francis Group
2022-12-01
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| Series: | Science and Technology of Advanced Materials: Methods |
| Subjects: | |
| Online Access: | http://dx.doi.org/10.1080/27660400.2022.2140021 |
| _version_ | 1797685797518835712 |
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| author | Hiroshi Sekiguchi Noboru Ohta Hideaki Ishibashi Hideitsu Hino Masaichiro Mizumaki |
| author_facet | Hiroshi Sekiguchi Noboru Ohta Hideaki Ishibashi Hideitsu Hino Masaichiro Mizumaki |
| author_sort | Hiroshi Sekiguchi |
| collection | DOAJ |
| description | We develop a method for calculating the minimum X-ray exposure time for X-ray solution scattering experiments using statistical and mathematical approaches to enhance the measurement efficiency while maintaining data quality. Experts can determine the X-ray exposure time for samples by investigating time-series data of scattering profiles and considering the quality of scattering profiles and the samples’ X-ray damage. In this study, we apply a statistical inequality to estimate the kernel density estimation method’s error to determine the minimum X-ray exposure time for protein solution scattering experiments and evaluate the method’s validity using the results of Guinier analysis as an indicator. |
| first_indexed | 2024-03-12T00:55:35Z |
| format | Article |
| id | doaj.art-cdd7c4004b514157a12c8092073066ef |
| institution | Directory Open Access Journal |
| issn | 2766-0400 |
| language | English |
| last_indexed | 2024-03-12T00:55:35Z |
| publishDate | 2022-12-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | Science and Technology of Advanced Materials: Methods |
| spelling | doaj.art-cdd7c4004b514157a12c8092073066ef2023-09-14T13:24:39ZengTaylor & Francis GroupScience and Technology of Advanced Materials: Methods2766-04002022-12-012142643410.1080/27660400.2022.21400212140021End-condition for solution small angle X-ray scattering measurements by kernel density estimationHiroshi Sekiguchi0Noboru Ohta1Hideaki Ishibashi2Hideitsu Hino3Masaichiro Mizumaki4Japan Synchrotron Radiation Research InstituteJapan Synchrotron Radiation Research InstituteKyushu Institute of TechnologyThe Institute of Statistical MathematicsJapan Synchrotron Radiation Research InstituteWe develop a method for calculating the minimum X-ray exposure time for X-ray solution scattering experiments using statistical and mathematical approaches to enhance the measurement efficiency while maintaining data quality. Experts can determine the X-ray exposure time for samples by investigating time-series data of scattering profiles and considering the quality of scattering profiles and the samples’ X-ray damage. In this study, we apply a statistical inequality to estimate the kernel density estimation method’s error to determine the minimum X-ray exposure time for protein solution scattering experiments and evaluate the method’s validity using the results of Guinier analysis as an indicator.http://dx.doi.org/10.1080/27660400.2022.2140021saxsbio-saxsoptimum exposureskernel density estimation |
| spellingShingle | Hiroshi Sekiguchi Noboru Ohta Hideaki Ishibashi Hideitsu Hino Masaichiro Mizumaki End-condition for solution small angle X-ray scattering measurements by kernel density estimation Science and Technology of Advanced Materials: Methods saxs bio-saxs optimum exposures kernel density estimation |
| title | End-condition for solution small angle X-ray scattering measurements by kernel density estimation |
| title_full | End-condition for solution small angle X-ray scattering measurements by kernel density estimation |
| title_fullStr | End-condition for solution small angle X-ray scattering measurements by kernel density estimation |
| title_full_unstemmed | End-condition for solution small angle X-ray scattering measurements by kernel density estimation |
| title_short | End-condition for solution small angle X-ray scattering measurements by kernel density estimation |
| title_sort | end condition for solution small angle x ray scattering measurements by kernel density estimation |
| topic | saxs bio-saxs optimum exposures kernel density estimation |
| url | http://dx.doi.org/10.1080/27660400.2022.2140021 |
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