The divergent opinions of regulatory authorities on roflumilast are puzzling but we need new drugs for treating chronic obstructive pulmonary disease

The divergent opinions of regulatory authorities on roflumilast are puzzling but we need new drugs for treating chronic obstructive pulmonary disease

Bibliographic Details
Main Author:	Mario Cazzola
Format:	Article
Language:	English
Published:	SAGE Publishing 2010-08-01
Series:	Therapeutic Advances in Respiratory Disease
Online Access:	https://doi.org/10.1177/1753465810377636

Similar Items

Roflumilast: A Review of Chronic Obstructive Pulmonary Disease (COPD) Treatment
by: Ita Octafia, et al.
Published: (2021-01-01)

Refractory erythema annulare centrifugum treated with roflumilast
by: Pamela Calderon, BS, et al.
Published: (2024-05-01)

Efficacy and safety of roflumilast in patients with chronic obstructive pulmonary disease: a systematic review and meta-analysis
by: Yuji Oba, et al.
Published: (2013-02-01)

Roflumilast, ursodeoxycholic acid and nucleinate efficiency in patients with chronic obstructive pulmonary disease with accompanying chronic non-stone cholecystitis.
by: Dudka T.V., et al.
Published: (2014-11-01)

Long-Term Safety of Roflumilast in Patients with Chronic Obstructive Pulmonary Disease, a Multinational Observational Database Cohort Study
by: Garbe E, et al.
Published: (2024-08-01)

Neurodermatitis of the scalp associated with trichotillomania treated with roflumilast cream 0.3%
by: Edith Hanna, MD, et al.
Published: (2025-02-01)

Roflumilast and dyspnea in patients with moderate to very severe chronic obstructive pulmonary disease: a pooled analysis of four clinical trials
by: Rennard SI, et al.
Published: (2014-06-01)

Roflumilast Powders for Chronic Obstructive Pulmonary Disease: Formulation Design and the Influence of Device, Inhalation Flow Rate, and Storage Relative Humidity on Aerosolization
by: Mohammad A. M. Momin, et al.
Published: (2021-08-01)

Topical roflumilast approved for psoriasis treatment
by: article Editorial
Published: (2022-10-01)

Roflumilast in COPD: a Brazilian perspective
by: Stirbulov R, et al.
Published: (2015-09-01)

The use of roflumilast in COPD: a review
by: Andrea Zanini, et al.
Published: (2015-08-01)

Body mass index, airflow obstruction, dyspnea, and exercise index is not modified after 6 months therapy with roflumilast in a cohort of patients with chronic obstructive pulmonary disease
by: Silvano Dragonieri, et al.
Published: (2016-01-01)

A longitudinal, retrospective cohort study on the impact of roflumilast on exacerbations and economic burden among chronic obstructive pulmonary disease patients in the real world
by: Wan Y, et al.
Published: (2015-10-01)

Anti-TNF alpha-induced paradoxical psoriasis treated with topical roflumilast 0.3%
by: Edith Hanna, MD, et al.
Published: (2024-06-01)

Roflumilast: the fourth Mousquetaire in COPD pharmacological treatment
by: Bruno Balbi
Published: (2015-08-01)

Vulnerable COPD patients with comorbidities: the role of roflumilast
by: Lipari M, et al.
Published: (2014-11-01)

Long-Acting Muscarinic Antagonists Under Investigational to Treat Chronic Obstructive Pulmonary Disease
by: Ora J, et al.
Published: (2020-12-01)

Hyperglycaemia and Chronic Obstructive Pulmonary Disease
by: Mario Cazzola, et al.
Published: (2023-11-01)

Roflumilast alleviates lung injury in rats with pneumococcal pneumonia
Published: (2024-10-01)

Roflumilast in Dermatology: A Newer Phosphodiesterase-4 Inhibitor
by: Suvesh Singh, et al.
Published: (2025-01-01)

Does roflumilast induce phagocytic activity in COPD patients?
by: Ghosh B, et al.
Published: (2015-09-01)

Roflumilast: a review of its use in the treatment of COPD
by: Wedzicha JA, et al.
Published: (2016-01-01)

Roflumilast: Review of Phosphodiesterase-4 Inhibitor as Asthma Therapy
by: Rafina Syfridiana, et al.
Published: (2021-08-01)

Analysis of the long-term effectiveness of a drug in the treatment of a chronic disease is the basis of rational pharmacotherapy (on the example of the use of roflumilast in the treatment of chronic obstructive pulmonary disease)
by: O. V. Zhukova, et al.
Published: (2020-09-01)

The Dosing Strategy to Improve Adherence to Roflumilast in Treatment for Chronic Obstructive Lung Disease: A Systemic Review and Meta-Analysis
by: Lee J, et al.
Published: (2024-03-01)

The future of inhalation therapy in chronic obstructive pulmonary disease
by: Mario Cazzola, et al.
Published: (2022-01-01)

Response to: Oba, Y. and Lone, N. (2013) Efficacy and safety of roflumilast in patients with chronic obstructive pulmonary disease: a systematic review and meta-analysis. 7: 13–24.
by: Shahid Siddiqui
Published: (2013-08-01)

Molecular Properties of Phosphodiesterase 4 and Its Inhibition by Roflumilast and Cilomilast
by: Hyun Jeong Kwak, et al.
Published: (2025-02-01)

Roflumilast attenuates allergen-induced inflammation in mild asthmatic subjects
by: Deschesnes Francine, et al.
Published: (2011-10-01)

Roflumilast: first phosphodiesterase 4 inhibitor approved for treatment of COPD
by: Mark A Giembycz, et al.
Published: (2010-07-01)

Roflumilast Suppresses Adipogenic Differentiation via AMPK Mediated Pathway
by: Wan Xu, et al.
Published: (2021-06-01)

Long-acting &beta;2-agonists (LABA) in chronic obstructive pulmonary disease: efficacy and safety
by: Andrea Rossi, et al.
Published: (2008-07-01)

Is myocardial work the piece of puzzle that we missed?
by: Marijana Tadic, et al.
Published: (2022-12-01)

Network Pharmacology and Experimental Verification Reveal the Regulatory Mechanism of Chuanbeimu in Treating Chronic Obstructive Pulmonary Disease
by: Xian M, et al.
Published: (2024-03-01)

Successful treatment of nail psoriasis with topical roflumilast: A case report
by: Leah A Johnston, et al.
Published: (2024-10-01)

Roflumilast tópico y oral en dermatología. Una revisión narrativa
by: M. Mansilla-Polo, et al.
Published: (2024-03-01)

[Translated aticle] Topical and Oral Roflumilast in Dermatology: A Narrative Review
by: M. Mansilla-Polo, et al.
Published: (2024-03-01)

Roflumilast is effective in reducing COPD related exacerbations and improving CAT score
by: Biagio Polla
Published: (2015-08-01)

Roflumilast succeeds where traditional therapy fails: a case report
by: Gabriella Guarnieri
Published: (2015-08-01)

Effect of roflumilast on inflammatory cells in the lungs of cigarette smoke-exposed mice
by: De Cunto Giovanna, et al.
Published: (2008-08-01)