Nutritional Assessment in Gastrointestinal Tumors: News from the 2020 ASCO and ESMO World GI Meetings
Nutritional risk screening and assessment of general nutritional status are of primary importance in the management of gastrointestinal cancers (GIC). Indeed, a major problem in these patients is the involuntary weight loss leading eventually to cachexia. With our review, we aimed at collecting the...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2020-09-01
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| Series: | Gastrointestinal Disorders |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2624-5647/2/3/28 |
| _version_ | 1797553129436217344 |
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| author | Federica Mascaretti Jessica Evangelista |
| author_facet | Federica Mascaretti Jessica Evangelista |
| author_sort | Federica Mascaretti |
| collection | DOAJ |
| description | Nutritional risk screening and assessment of general nutritional status are of primary importance in the management of gastrointestinal cancers (GIC). Indeed, a major problem in these patients is the involuntary weight loss leading eventually to cachexia. With our review, we aimed at collecting the most recent advances in nutritional assessment of patients with GIC. All the abstracts presented both at the 2020 ASCO and ESMO World GI meetings were considered and a total number of 12 abstracts were selected, reporting colorectal, gastric, esophageal, and pancreatic cancer (PC) series. In some of the analyzed series, pathological conditions such as cachexia and sarcopenia had prognostic significance on clinical outcomes. One abstract reported the results of a phase I trial with the use of a novel interleukin-1-alpha antagonist, bermekimab. Its association with standard chemotherapy in advanced PC brought an improved patients’ performance during treatment. Insufficient attention is paid to the nutritional status of patients with GIC both at screening and during specific cancer treatment. The use of antropometric measurements, together with nutritional assessment tools, may facilitate the clinical evaluation of these patients. Large randomized trials are warranted in order to clarify the real impact of nutritional interventions on clinical outcomes. |
| first_indexed | 2024-03-10T16:11:02Z |
| format | Article |
| id | doaj.art-cddd8b4602ce41a6b159f84a1a950a9a |
| institution | Directory Open Access Journal |
| issn | 2624-5647 |
| language | English |
| last_indexed | 2024-03-10T16:11:02Z |
| publishDate | 2020-09-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Gastrointestinal Disorders |
| spelling | doaj.art-cddd8b4602ce41a6b159f84a1a950a9a2023-11-20T14:28:02ZengMDPI AGGastrointestinal Disorders2624-56472020-09-012331031710.3390/gidisord2030028Nutritional Assessment in Gastrointestinal Tumors: News from the 2020 ASCO and ESMO World GI MeetingsFederica Mascaretti0Jessica Evangelista1Unità di Gastroenterologia ed Endoscopia, Fondazione IRCCS Ca’ Granda Ospedale Maggiore Policlinico, 20019 Milano, ItalyUnità Operativa complessa di Chirurgia Toracica, Dipartimento di Scienze Mediche e Chirurgiche, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, 00100 Rome, ItalyNutritional risk screening and assessment of general nutritional status are of primary importance in the management of gastrointestinal cancers (GIC). Indeed, a major problem in these patients is the involuntary weight loss leading eventually to cachexia. With our review, we aimed at collecting the most recent advances in nutritional assessment of patients with GIC. All the abstracts presented both at the 2020 ASCO and ESMO World GI meetings were considered and a total number of 12 abstracts were selected, reporting colorectal, gastric, esophageal, and pancreatic cancer (PC) series. In some of the analyzed series, pathological conditions such as cachexia and sarcopenia had prognostic significance on clinical outcomes. One abstract reported the results of a phase I trial with the use of a novel interleukin-1-alpha antagonist, bermekimab. Its association with standard chemotherapy in advanced PC brought an improved patients’ performance during treatment. Insufficient attention is paid to the nutritional status of patients with GIC both at screening and during specific cancer treatment. The use of antropometric measurements, together with nutritional assessment tools, may facilitate the clinical evaluation of these patients. Large randomized trials are warranted in order to clarify the real impact of nutritional interventions on clinical outcomes.https://www.mdpi.com/2624-5647/2/3/28nutritiongastrointestinal cancerscachexiaBMImalnutritiongastric cancer |
| spellingShingle | Federica Mascaretti Jessica Evangelista Nutritional Assessment in Gastrointestinal Tumors: News from the 2020 ASCO and ESMO World GI Meetings Gastrointestinal Disorders nutrition gastrointestinal cancers cachexia BMI malnutrition gastric cancer |
| title | Nutritional Assessment in Gastrointestinal Tumors: News from the 2020 ASCO and ESMO World GI Meetings |
| title_full | Nutritional Assessment in Gastrointestinal Tumors: News from the 2020 ASCO and ESMO World GI Meetings |
| title_fullStr | Nutritional Assessment in Gastrointestinal Tumors: News from the 2020 ASCO and ESMO World GI Meetings |
| title_full_unstemmed | Nutritional Assessment in Gastrointestinal Tumors: News from the 2020 ASCO and ESMO World GI Meetings |
| title_short | Nutritional Assessment in Gastrointestinal Tumors: News from the 2020 ASCO and ESMO World GI Meetings |
| title_sort | nutritional assessment in gastrointestinal tumors news from the 2020 asco and esmo world gi meetings |
| topic | nutrition gastrointestinal cancers cachexia BMI malnutrition gastric cancer |
| url | https://www.mdpi.com/2624-5647/2/3/28 |
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