MiR-371a-5p Positively Associates with Hepatocellular Carcinoma Malignancy but Sensitizes Cancer Cells to Oxaliplatin by Suppressing BECN1-Dependent Autophagy

MiR-371a-5p Positively Associates with Hepatocellular Carcinoma Malignancy but Sensitizes Cancer Cells to Oxaliplatin by Suppressing BECN1-Dependent Autophagy

Oxaliplatin (OXA)-based chemotherapy demonstrates active efficacy in advanced hepatocellular carcinoma (HCC), while resistance development limits its clinical efficacy. Thus, identifying resistance-related molecules and underlying mechanisms contributes to improving the therapeutic efficacy of HCC p...

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Bibliographic Details
Main Authors: Zhenbing Lv, Xin Qiu, Pu Jin, Zhaodong Li, Yan Zhang, Lei Lv, Fangzhou Song
Format: Article
Language:English
Published: MDPI AG 2022-10-01
Series:Life
Subjects:
hepatocellular carcinoma
miR-371a-5p
BECN1
autophagy
oxaliplatin
resistance
Online Access:https://www.mdpi.com/2075-1729/12/10/1651

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