The Impact of an Educational Video on Clinical Trial Enrollment and Knowledge in Ethnic Minorities: A Randomized Control Trial
Introduction: Innovative methods to increase awareness about clinical trials and address barriers associated with low participation among racial/ethnic minorities are desperately needed. African Americans comprise 5% of all clinical trial participants, and Hispanics make up 1%. Use of multimedia edu...
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2019-04-01
|
| Series: | Frontiers in Public Health |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/article/10.3389/fpubh.2019.00104/full |
| _version_ | 1819241096169914368 |
|---|---|
| author | Jeannine S. Skinner Alecia M. Fair Alexis S. Holman Alaina P. Boyer Consuelo H. Wilkins Consuelo H. Wilkins |
| author_facet | Jeannine S. Skinner Alecia M. Fair Alexis S. Holman Alaina P. Boyer Consuelo H. Wilkins Consuelo H. Wilkins |
| author_sort | Jeannine S. Skinner |
| collection | DOAJ |
| description | Introduction: Innovative methods to increase awareness about clinical trials and address barriers associated with low participation among racial/ethnic minorities are desperately needed. African Americans comprise 5% of all clinical trial participants, and Hispanics make up 1%. Use of multimedia educational material has shown promise as an effective strategy to increase minority clinical trial enrollment. However, this approach has not been broadly implemented. We tested the effect of a video educational program on clinical trial knowledge and enrollment in a sample of oncology outpatients.Methods: A randomized controlled trial was conducted with 63 oncology patients without previous history of clinical trial participation. Participants were randomly assigned to the intervention, to watch a clinical trial educational video in the office, or to the control group which did not receive in-office education. The Clinical Trial Knowledge survey was administered before the intervention and 1 week after the intervention. Participation in clinical trials was assessed 1-year post study participation. Results for white participants and ethnic minorities were compared. Ethnicity was self-reported through the electronic health record and confirmed by self-reporting on questionnaire.Results: Sixty-three participants were recruited in this study. At 1-year follow-up, 3 participants enrolled in clinical trials in the study group which had received office-based video intervention and 2 participants enrolled in the control group (Z = 0.39, p = 0.69). These results were not statistically significant. Impact of the intervention by ethnicity could not be assessed due to low total clinical trial enrollment. The video intervention did not change knowledge, attitudes, or barriers as measured by the Clinical Trial Knowledge Survey. Minority participants did report significantly more negative beliefs and barriers to participation than white participants.Conclusions: Increasing awareness and knowledge about clinical trials in underrepresented communities is an important step to providing opportunities for participation. Future studies should focus on how to address the negative expectations of clinical trials and the greater information needs in minority populations. Tailored or personalized messaging may address negative perceptions of clinical trial participation. |
| first_indexed | 2024-12-23T14:18:28Z |
| format | Article |
| id | doaj.art-cde1c8caa8824328af03f69ab509f406 |
| institution | Directory Open Access Journal |
| issn | 2296-2565 |
| language | English |
| last_indexed | 2024-12-23T14:18:28Z |
| publishDate | 2019-04-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Public Health |
| spelling | doaj.art-cde1c8caa8824328af03f69ab509f4062022-12-21T17:43:51ZengFrontiers Media S.A.Frontiers in Public Health2296-25652019-04-01710.3389/fpubh.2019.00104446945The Impact of an Educational Video on Clinical Trial Enrollment and Knowledge in Ethnic Minorities: A Randomized Control TrialJeannine S. Skinner0Alecia M. Fair1Alexis S. Holman2Alaina P. Boyer3Consuelo H. Wilkins4Consuelo H. Wilkins5Interdisciplinary Gerontology Program, Department of Psychological Sciences, University of North Carolina at Charlotte, Charlotte, NC, United StatesMeharry-Vanderbilt Alliance, Vanderbilt University Medical Center, Nashville, TN, United StatesSarah Cannon Research Institute, Sarah Cannon, Nashville, TN, United StatesNational Health Care for the Homeless Council, Nashville, TN, United StatesMeharry-Vanderbilt Alliance, Vanderbilt University Medical Center, Nashville, TN, United StatesDepartment of Medicine, Meharry Medical College, Nashville, TN, United StatesIntroduction: Innovative methods to increase awareness about clinical trials and address barriers associated with low participation among racial/ethnic minorities are desperately needed. African Americans comprise 5% of all clinical trial participants, and Hispanics make up 1%. Use of multimedia educational material has shown promise as an effective strategy to increase minority clinical trial enrollment. However, this approach has not been broadly implemented. We tested the effect of a video educational program on clinical trial knowledge and enrollment in a sample of oncology outpatients.Methods: A randomized controlled trial was conducted with 63 oncology patients without previous history of clinical trial participation. Participants were randomly assigned to the intervention, to watch a clinical trial educational video in the office, or to the control group which did not receive in-office education. The Clinical Trial Knowledge survey was administered before the intervention and 1 week after the intervention. Participation in clinical trials was assessed 1-year post study participation. Results for white participants and ethnic minorities were compared. Ethnicity was self-reported through the electronic health record and confirmed by self-reporting on questionnaire.Results: Sixty-three participants were recruited in this study. At 1-year follow-up, 3 participants enrolled in clinical trials in the study group which had received office-based video intervention and 2 participants enrolled in the control group (Z = 0.39, p = 0.69). These results were not statistically significant. Impact of the intervention by ethnicity could not be assessed due to low total clinical trial enrollment. The video intervention did not change knowledge, attitudes, or barriers as measured by the Clinical Trial Knowledge Survey. Minority participants did report significantly more negative beliefs and barriers to participation than white participants.Conclusions: Increasing awareness and knowledge about clinical trials in underrepresented communities is an important step to providing opportunities for participation. Future studies should focus on how to address the negative expectations of clinical trials and the greater information needs in minority populations. Tailored or personalized messaging may address negative perceptions of clinical trial participation.https://www.frontiersin.org/article/10.3389/fpubh.2019.00104/fullclinical trialsethnic groupsminority groupspatientscancereducation |
| spellingShingle | Jeannine S. Skinner Alecia M. Fair Alexis S. Holman Alaina P. Boyer Consuelo H. Wilkins Consuelo H. Wilkins The Impact of an Educational Video on Clinical Trial Enrollment and Knowledge in Ethnic Minorities: A Randomized Control Trial Frontiers in Public Health clinical trials ethnic groups minority groups patients cancer education |
| title | The Impact of an Educational Video on Clinical Trial Enrollment and Knowledge in Ethnic Minorities: A Randomized Control Trial |
| title_full | The Impact of an Educational Video on Clinical Trial Enrollment and Knowledge in Ethnic Minorities: A Randomized Control Trial |
| title_fullStr | The Impact of an Educational Video on Clinical Trial Enrollment and Knowledge in Ethnic Minorities: A Randomized Control Trial |
| title_full_unstemmed | The Impact of an Educational Video on Clinical Trial Enrollment and Knowledge in Ethnic Minorities: A Randomized Control Trial |
| title_short | The Impact of an Educational Video on Clinical Trial Enrollment and Knowledge in Ethnic Minorities: A Randomized Control Trial |
| title_sort | impact of an educational video on clinical trial enrollment and knowledge in ethnic minorities a randomized control trial |
| topic | clinical trials ethnic groups minority groups patients cancer education |
| url | https://www.frontiersin.org/article/10.3389/fpubh.2019.00104/full |
| work_keys_str_mv | AT jeanninesskinner theimpactofaneducationalvideoonclinicaltrialenrollmentandknowledgeinethnicminoritiesarandomizedcontroltrial AT aleciamfair theimpactofaneducationalvideoonclinicaltrialenrollmentandknowledgeinethnicminoritiesarandomizedcontroltrial AT alexissholman theimpactofaneducationalvideoonclinicaltrialenrollmentandknowledgeinethnicminoritiesarandomizedcontroltrial AT alainapboyer theimpactofaneducationalvideoonclinicaltrialenrollmentandknowledgeinethnicminoritiesarandomizedcontroltrial AT consuelohwilkins theimpactofaneducationalvideoonclinicaltrialenrollmentandknowledgeinethnicminoritiesarandomizedcontroltrial AT consuelohwilkins theimpactofaneducationalvideoonclinicaltrialenrollmentandknowledgeinethnicminoritiesarandomizedcontroltrial AT jeanninesskinner impactofaneducationalvideoonclinicaltrialenrollmentandknowledgeinethnicminoritiesarandomizedcontroltrial AT aleciamfair impactofaneducationalvideoonclinicaltrialenrollmentandknowledgeinethnicminoritiesarandomizedcontroltrial AT alexissholman impactofaneducationalvideoonclinicaltrialenrollmentandknowledgeinethnicminoritiesarandomizedcontroltrial AT alainapboyer impactofaneducationalvideoonclinicaltrialenrollmentandknowledgeinethnicminoritiesarandomizedcontroltrial AT consuelohwilkins impactofaneducationalvideoonclinicaltrialenrollmentandknowledgeinethnicminoritiesarandomizedcontroltrial AT consuelohwilkins impactofaneducationalvideoonclinicaltrialenrollmentandknowledgeinethnicminoritiesarandomizedcontroltrial |