Innate sensing of HIV-infected cells.

Innate sensing of HIV-infected cells.

Cell-free HIV-1 virions are poor stimulators of type I interferon (IFN) production. We examined here how HIV-infected cells are recognized by plasmacytoid dendritic cells (pDCs) and by other cells. We show that infected lymphocytes are more potent inducers of IFN than virions. There are target cell-...

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Podrobná bibliografie
Hlavní autoři: Alice Lepelley, Stéphanie Louis, Marion Sourisseau, Helen K W Law, Julien Pothlichet, Clémentine Schilte, Laurence Chaperot, Joël Plumas, Richard E Randall, Mustapha Si-Tahar, Fabrizio Mammano, Matthew L Albert, Olivier Schwartz
Médium: Článek
Jazyk:English
Vydáno: Public Library of Science (PLoS) 2011-02-01
Edice:PLoS Pathogens
On-line přístup:http://europepmc.org/articles/PMC3040675?pdf=render

Internet

http://europepmc.org/articles/PMC3040675?pdf=render

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