To what extent naringenin binding and membrane depolarization shape mitoBK channel gating-A machine learning approach.
The large conductance voltage- and Ca2+-activated K+ channels from the inner mitochondrial membrane (mitoBK) are modulated by a number of factors. Among them flavanones, including naringenin (Nar), arise as a promising group of mitoBK channel regulators from a pharmacological point of view. It is we...
| Hauptverfasser: | , , , |
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| Format: | Artikel |
| Sprache: | English |
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Public Library of Science (PLoS)
2022-07-01
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| Schriftenreihe: | PLoS Computational Biology |
| Online Zugang: | https://doi.org/10.1371/journal.pcbi.1010315 |