Measuring the amount of serum albumin in burn patients and the relationship between the burned area and length of hospital stay
Background: Albumin is one of the most important proteins in the body by several important functions, it is essential in the maintenance of normal plasma colloid oncotic pressure and is the primary serum binding protein responsible for the transport of various substances in the circulation including...
Main Authors: | , , , |
---|---|
Format: | Article |
Language: | fas |
Published: |
Tehran University of Medical Sciences
2017-08-01
|
Series: | Tehran University Medical Journal |
Subjects: | |
Online Access: | http://tumj.tums.ac.ir/browse.php?a_code=A-10-25-5600&slc_lang=en&sid=1 |
_version_ | 1818935808791412736 |
---|---|
author | Maryam Roham Mohammad Javad Fatemi Mitra Niazi Mahnoush Momeni |
author_facet | Maryam Roham Mohammad Javad Fatemi Mitra Niazi Mahnoush Momeni |
author_sort | Maryam Roham |
collection | DOAJ |
description | Background: Albumin is one of the most important proteins in the body by several important functions, it is essential in the maintenance of normal plasma colloid oncotic pressure and is the primary serum binding protein responsible for the transport of various substances in the circulation including fatty acids, hormones, and drugs. Decrease in the amount of serum Albumin (Hypoalbuminemia) is a common finding in the burn patients, but its relationship with mortality is not accurately clear. Our purpose of this study was to measure the amount of Albumin serum in burn patients and find out its relationship between the burned area and length of hospital stay.
Methods: This cross-sectional study was conducted on patients aged over 16 years who referred to the Motahari Hospital of September 2014 to February 2015 in the first 24 hours of their referral. The amount of Albumin was measured in two groups of discharged patients and patients who died while hospitalized, one week after hospital stay and in the time of discharge and death; and its relationship in terms of each other was determined by statistical analysis. We also assessed the relationship between burn and duration of hospital stay with the amount of Albumin on the day of patient’s admission.
Results: This study showed that the average amount of albumin in the group of discharged patients in the time of admission, one week after and during admission was significantly higher than the group of expired patients (P<0.0001). Also there was a significant relation between the burned area and the amount of albumin (P<0.0001). The more the burned area, the less the amount of Albumin. But there was no significant relationship between the amount of albumin with age and length of hospital stay.
Conclusion: Measuring the level of Albumin is one of the yardsticks that can be used for prognosis of recovery or death of burn patients, and its assessment at regular intervals in burn patients is essential. |
first_indexed | 2024-12-20T05:26:04Z |
format | Article |
id | doaj.art-cdebc2d631834c3883a250803b0d0c53 |
institution | Directory Open Access Journal |
issn | 1683-1764 1735-7322 |
language | fas |
last_indexed | 2024-12-20T05:26:04Z |
publishDate | 2017-08-01 |
publisher | Tehran University of Medical Sciences |
record_format | Article |
series | Tehran University Medical Journal |
spelling | doaj.art-cdebc2d631834c3883a250803b0d0c532022-12-21T19:51:53ZfasTehran University of Medical SciencesTehran University Medical Journal1683-17641735-73222017-08-01755387392Measuring the amount of serum albumin in burn patients and the relationship between the burned area and length of hospital stayMaryam Roham0Mohammad Javad Fatemi1Mitra Niazi2Mahnoush Momeni3 Department of Infectious Diseases, Burn Research Center, Iran University of Medical Sciences, Tehran, Iran. Department of Plastic and Reconstructive Surgery, Burn Research Center, Iran University of Medical Sciences, Tehran, Iran. Department of Occupational Therapy, Burn Research Center, Iran University of Medical Sciences, Tehran, Iran. Department of General Surgery, Burn Research Center, Iran University of Medical Sciences, Tehran, Iran. Background: Albumin is one of the most important proteins in the body by several important functions, it is essential in the maintenance of normal plasma colloid oncotic pressure and is the primary serum binding protein responsible for the transport of various substances in the circulation including fatty acids, hormones, and drugs. Decrease in the amount of serum Albumin (Hypoalbuminemia) is a common finding in the burn patients, but its relationship with mortality is not accurately clear. Our purpose of this study was to measure the amount of Albumin serum in burn patients and find out its relationship between the burned area and length of hospital stay. Methods: This cross-sectional study was conducted on patients aged over 16 years who referred to the Motahari Hospital of September 2014 to February 2015 in the first 24 hours of their referral. The amount of Albumin was measured in two groups of discharged patients and patients who died while hospitalized, one week after hospital stay and in the time of discharge and death; and its relationship in terms of each other was determined by statistical analysis. We also assessed the relationship between burn and duration of hospital stay with the amount of Albumin on the day of patient’s admission. Results: This study showed that the average amount of albumin in the group of discharged patients in the time of admission, one week after and during admission was significantly higher than the group of expired patients (P<0.0001). Also there was a significant relation between the burned area and the amount of albumin (P<0.0001). The more the burned area, the less the amount of Albumin. But there was no significant relationship between the amount of albumin with age and length of hospital stay. Conclusion: Measuring the level of Albumin is one of the yardsticks that can be used for prognosis of recovery or death of burn patients, and its assessment at regular intervals in burn patients is essential.http://tumj.tums.ac.ir/browse.php?a_code=A-10-25-5600&slc_lang=en&sid=1burns cross-sectional studies hypoalbuminemia length of stay serum albumin |
spellingShingle | Maryam Roham Mohammad Javad Fatemi Mitra Niazi Mahnoush Momeni Measuring the amount of serum albumin in burn patients and the relationship between the burned area and length of hospital stay Tehran University Medical Journal burns cross-sectional studies hypoalbuminemia length of stay serum albumin |
title | Measuring the amount of serum albumin in burn patients and the relationship between the burned area and length of hospital stay |
title_full | Measuring the amount of serum albumin in burn patients and the relationship between the burned area and length of hospital stay |
title_fullStr | Measuring the amount of serum albumin in burn patients and the relationship between the burned area and length of hospital stay |
title_full_unstemmed | Measuring the amount of serum albumin in burn patients and the relationship between the burned area and length of hospital stay |
title_short | Measuring the amount of serum albumin in burn patients and the relationship between the burned area and length of hospital stay |
title_sort | measuring the amount of serum albumin in burn patients and the relationship between the burned area and length of hospital stay |
topic | burns cross-sectional studies hypoalbuminemia length of stay serum albumin |
url | http://tumj.tums.ac.ir/browse.php?a_code=A-10-25-5600&slc_lang=en&sid=1 |
work_keys_str_mv | AT maryamroham measuringtheamountofserumalbumininburnpatientsandtherelationshipbetweentheburnedareaandlengthofhospitalstay AT mohammadjavadfatemi measuringtheamountofserumalbumininburnpatientsandtherelationshipbetweentheburnedareaandlengthofhospitalstay AT mitraniazi measuringtheamountofserumalbumininburnpatientsandtherelationshipbetweentheburnedareaandlengthofhospitalstay AT mahnoushmomeni measuringtheamountofserumalbumininburnpatientsandtherelationshipbetweentheburnedareaandlengthofhospitalstay |