Molecular Signaling to Preserve Mitochondrial Integrity against Ischemic Stress in the Heart: Rescue or Remove Mitochondria in Danger

Molecular Signaling to Preserve Mitochondrial Integrity against Ischemic Stress in the Heart: Rescue or Remove Mitochondria in Danger

Cardiovascular diseases are one of the leading causes of death and global health problems worldwide, and ischemic heart disease is the most common cause of heart failure (HF). The heart is a high-energy demanding organ, and myocardial energy reserves are limited. Mitochondria are the powerhouses of...

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Bibliographic Details
Main Authors:	Justin D. Yu, Shigeki Miyamoto
Format:	Article
Language:	English
Published:	MDPI AG 2021-11-01
Series:	Cells
Subjects:	mitochondria cell death BCL-2 family proteins mPTP pro-survival signaling mitophagy
Online Access:	https://www.mdpi.com/2073-4409/10/12/3330

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