Unveiling the transcriptomic landscape and the potential antagonist feedback mechanisms of TGF-β superfamily signaling module in bone and osteoporosis

Unveiling the transcriptomic landscape and the potential antagonist feedback mechanisms of TGF-β superfamily signaling module in bone and osteoporosis

Abstract Background TGF-β superfamily signaling is indispensable for bone homeostasis. However, the global expression profiles of all the genes that make up this signaling module in bone and bone-related diseases have not yet been well characterized. Methods Transcriptomic datasets from human bone m...

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Bibliographic Details
Main Authors: Ying-Wen Wang, Wen-Yu Lin, Fang-Ju Wu, Ching-Wei Luo
Format: Article
Language:English
Published: BMC 2022-11-01
Series:Cell Communication and Signaling
Subjects:
Antagonist
BMP8
Mesenchymal stem cell
Osteoporosis
TGF-β superfamily
Online Access:https://doi.org/10.1186/s12964-022-01002-2

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