Exaggerated postnatal surge of orexin neurons and the effects of elimination of excess orexin on blood pressure and exaggerated chemoreflex in spontaneously hypertensive rats

Exaggerated postnatal surge of orexin neurons and the effects of elimination of excess orexin on blood pressure and exaggerated chemoreflex in spontaneously hypertensive rats

An overactive orexin (OX) system is associated with neurogenic hypertension and an exaggerated chemoreflex in spontaneously hypertensive rats (SHRs). However, the chronology and mechanism of this association is unclear. We hypothesized that increased postnatal neurogenesis of OX neurons in SHRs prec...

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Bibliografiske detaljer
Main Authors:	Savannah Lusk, Alexander M. Moushey, Nicholas Iwakoshi, Christopher G. Wilson, Aihua Li, Russell Ray
Format:	Article
Sprog:	English
Udgivet:	Frontiers Media S.A. 2024-10-01
Serier:	Frontiers in Physiology
Fag:	hypertension orexin postnatal neurogenesis hypercapnia hypercapnic chemoreflex
Online adgang:	https://www.frontiersin.org/articles/10.3389/fphys.2024.1341649/full

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