Endoscopic management of Zenker’s diverticulum

Zenker’s diverticulum (ZD) is a rare condition that predominantly effects elderly population. Dysphagia and regurgitation are the common presenting symptoms in patients with ZD. Flexible endoscopic diverticulotomy (FED) of the cricopharyngeal septum is the mainstay of management in symptomatic ZD. T...

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Main Authors: Zaheer Nabi, Duvuur Nageshwar Reddy
Format: Article
Language:English
Published: Society of Gastrointestinal Intervention 2020-04-01
Series:International Journal of Gastrointestinal Intervention
Subjects:
Online Access:http://www.ijgii.org/journal/view.html?doi=10.18528/ijgii200004
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author Zaheer Nabi
Duvuur Nageshwar Reddy
author_facet Zaheer Nabi
Duvuur Nageshwar Reddy
author_sort Zaheer Nabi
collection DOAJ
description Zenker’s diverticulum (ZD) is a rare condition that predominantly effects elderly population. Dysphagia and regurgitation are the common presenting symptoms in patients with ZD. Flexible endoscopic diverticulotomy (FED) of the cricopharyngeal septum is the mainstay of management in symptomatic ZD. The outcomes of FED compare favorably to open surgical and trans-oral rigid endoscopic treatment methods. Moreover, FED is associated with relatively fewer morbidities as compared to surgery. Bleeding and micro-perforation are the most commonly reported immediate adverse events. Majority of the adverse events are mild and severe adverse events are rare with FED. Recurrence of symptoms remain the most important long-term concern after FED. Nevertheless, majority of the recurrences respond to a repeat session of endoscopic treatment. Lately, new electrosurgical knives and novel endoscopic techniques of cricopharyngeal myotomy have been evaluated for the treatment of ZD. Novel techniques include double incision with snare resection and submucosal tunneling endoscopic septum division. The proposed advantage with these techniques is possible reduced incidence of recurrences after endoscopic treatment. Randomized comparison studies are required between new and conventional flexible endoscopic techniques. In addition, standardized reporting of clinical success, and adverse events is required in future studies.
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spelling doaj.art-cdf2874963ce44958dfb50d987e2cddd2022-12-21T17:45:51ZengSociety of Gastrointestinal InterventionInternational Journal of Gastrointestinal Intervention2636-00042020-04-0192788510.18528/ijgii20000410.18528/ijgii200004Endoscopic management of Zenker’s diverticulumZaheer Nabi0Duvuur Nageshwar Reddy1Department of Gastroenterology, Asian Institute of Gastroenterology, Hyderabad, IndiaDepartment of Gastroenterology, Asian Institute of Gastroenterology, Hyderabad, IndiaZenker’s diverticulum (ZD) is a rare condition that predominantly effects elderly population. Dysphagia and regurgitation are the common presenting symptoms in patients with ZD. Flexible endoscopic diverticulotomy (FED) of the cricopharyngeal septum is the mainstay of management in symptomatic ZD. The outcomes of FED compare favorably to open surgical and trans-oral rigid endoscopic treatment methods. Moreover, FED is associated with relatively fewer morbidities as compared to surgery. Bleeding and micro-perforation are the most commonly reported immediate adverse events. Majority of the adverse events are mild and severe adverse events are rare with FED. Recurrence of symptoms remain the most important long-term concern after FED. Nevertheless, majority of the recurrences respond to a repeat session of endoscopic treatment. Lately, new electrosurgical knives and novel endoscopic techniques of cricopharyngeal myotomy have been evaluated for the treatment of ZD. Novel techniques include double incision with snare resection and submucosal tunneling endoscopic septum division. The proposed advantage with these techniques is possible reduced incidence of recurrences after endoscopic treatment. Randomized comparison studies are required between new and conventional flexible endoscopic techniques. In addition, standardized reporting of clinical success, and adverse events is required in future studies.http://www.ijgii.org/journal/view.html?doi=10.18528/ijgii200004endoscopy; myotomy; zenker diverticulum
spellingShingle Zaheer Nabi
Duvuur Nageshwar Reddy
Endoscopic management of Zenker’s diverticulum
International Journal of Gastrointestinal Intervention
endoscopy; myotomy; zenker diverticulum
title Endoscopic management of Zenker’s diverticulum
title_full Endoscopic management of Zenker’s diverticulum
title_fullStr Endoscopic management of Zenker’s diverticulum
title_full_unstemmed Endoscopic management of Zenker’s diverticulum
title_short Endoscopic management of Zenker’s diverticulum
title_sort endoscopic management of zenker s diverticulum
topic endoscopy; myotomy; zenker diverticulum
url http://www.ijgii.org/journal/view.html?doi=10.18528/ijgii200004
work_keys_str_mv AT zaheernabi endoscopicmanagementofzenkersdiverticulum
AT duvuurnageshwarreddy endoscopicmanagementofzenkersdiverticulum