Risk factors for basal cell carcinoma: a case-control study
A controlled trial was performed with the purpose of investigating which factors could be considered of significant risk for the development of basal cell carcinoma. A total of 259 cases of basal cell carcinoma diagnosed from July 1991 to July 1992 were compared with 518 controls matched for age and...
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Language: | English |
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Universidade de São Paulo
1995-01-01
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Series: | Revista de Saúde Pública |
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Online Access: | http://www.scielosp.org/scielo.php?script=sci_arttext&pid=S0034-89101995000100006 |
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author | Maia Marcus Proença Nelson Guimarães Moraes José Cássio de |
author_facet | Maia Marcus Proença Nelson Guimarães Moraes José Cássio de |
author_sort | Maia Marcus |
collection | DOAJ |
description | A controlled trial was performed with the purpose of investigating which factors could be considered of significant risk for the development of basal cell carcinoma. A total of 259 cases of basal cell carcinoma diagnosed from July 1991 to July 1992 were compared with 518 controls matched for age and sex. All subjects in both groups were white. Protocol data were submitted to statistical analysis by the chi-square test and by multiple conditional logistic regression analysis and the following conclusions were reached: 1) light skin color (types I and II of the Fitzpatrick classification), odds ratio of 2.8; outdoor work under constant sunlight, odds ratio of 5.0; the presence of actinic lesions due to exposure to the sun, odds ratio of 4.9, are risk factors perse. 2) Type III skin in the Fitzpatrick classification only represents a risk factor when the patient reports a history of intense sunburns, but not in the absence of such a history. 3) Sunburns per se do not represent a risk factor althorig the point made in item 2 of these conclusions is valid. 4) Other suspected risk factors whose significance was not confirmed by multiple conditioned logistic regression analysis were: residence in rural areas, light eyes and blond hair color, extent of the awareness of the "sun x skin cancer" relationship, familial occurrence of skin cancer, excessive exposure to the sun, and freckles appearing in childhood. |
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issn | 0034-8910 1518-8787 |
language | English |
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publishDate | 1995-01-01 |
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spelling | doaj.art-cdf45b7fedc24226865f2537d4c6534d2022-12-22T00:05:57ZengUniversidade de São PauloRevista de Saúde Pública0034-89101518-87871995-01-012912737Risk factors for basal cell carcinoma: a case-control studyMaia MarcusProença Nelson GuimarãesMoraes José Cássio deA controlled trial was performed with the purpose of investigating which factors could be considered of significant risk for the development of basal cell carcinoma. A total of 259 cases of basal cell carcinoma diagnosed from July 1991 to July 1992 were compared with 518 controls matched for age and sex. All subjects in both groups were white. Protocol data were submitted to statistical analysis by the chi-square test and by multiple conditional logistic regression analysis and the following conclusions were reached: 1) light skin color (types I and II of the Fitzpatrick classification), odds ratio of 2.8; outdoor work under constant sunlight, odds ratio of 5.0; the presence of actinic lesions due to exposure to the sun, odds ratio of 4.9, are risk factors perse. 2) Type III skin in the Fitzpatrick classification only represents a risk factor when the patient reports a history of intense sunburns, but not in the absence of such a history. 3) Sunburns per se do not represent a risk factor althorig the point made in item 2 of these conclusions is valid. 4) Other suspected risk factors whose significance was not confirmed by multiple conditioned logistic regression analysis were: residence in rural areas, light eyes and blond hair color, extent of the awareness of the "sun x skin cancer" relationship, familial occurrence of skin cancer, excessive exposure to the sun, and freckles appearing in childhood.http://www.scielosp.org/scielo.php?script=sci_arttext&pid=S0034-89101995000100006Carcinoma, basal cell/epidemiologyRisk factors |
spellingShingle | Maia Marcus Proença Nelson Guimarães Moraes José Cássio de Risk factors for basal cell carcinoma: a case-control study Revista de Saúde Pública Carcinoma, basal cell/epidemiology Risk factors |
title | Risk factors for basal cell carcinoma: a case-control study |
title_full | Risk factors for basal cell carcinoma: a case-control study |
title_fullStr | Risk factors for basal cell carcinoma: a case-control study |
title_full_unstemmed | Risk factors for basal cell carcinoma: a case-control study |
title_short | Risk factors for basal cell carcinoma: a case-control study |
title_sort | risk factors for basal cell carcinoma a case control study |
topic | Carcinoma, basal cell/epidemiology Risk factors |
url | http://www.scielosp.org/scielo.php?script=sci_arttext&pid=S0034-89101995000100006 |
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