Risk factors for basal cell carcinoma: a case-control study

A controlled trial was performed with the purpose of investigating which factors could be considered of significant risk for the development of basal cell carcinoma. A total of 259 cases of basal cell carcinoma diagnosed from July 1991 to July 1992 were compared with 518 controls matched for age and...

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Main Authors: Maia Marcus, Proença Nelson Guimarães, Moraes José Cássio de
Format: Article
Language:English
Published: Universidade de São Paulo 1995-01-01
Series:Revista de Saúde Pública
Subjects:
Online Access:http://www.scielosp.org/scielo.php?script=sci_arttext&pid=S0034-89101995000100006
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author Maia Marcus
Proença Nelson Guimarães
Moraes José Cássio de
author_facet Maia Marcus
Proença Nelson Guimarães
Moraes José Cássio de
author_sort Maia Marcus
collection DOAJ
description A controlled trial was performed with the purpose of investigating which factors could be considered of significant risk for the development of basal cell carcinoma. A total of 259 cases of basal cell carcinoma diagnosed from July 1991 to July 1992 were compared with 518 controls matched for age and sex. All subjects in both groups were white. Protocol data were submitted to statistical analysis by the chi-square test and by multiple conditional logistic regression analysis and the following conclusions were reached: 1) light skin color (types I and II of the Fitzpatrick classification), odds ratio of 2.8; outdoor work under constant sunlight, odds ratio of 5.0; the presence of actinic lesions due to exposure to the sun, odds ratio of 4.9, are risk factors perse. 2) Type III skin in the Fitzpatrick classification only represents a risk factor when the patient reports a history of intense sunburns, but not in the absence of such a history. 3) Sunburns per se do not represent a risk factor althorig the point made in item 2 of these conclusions is valid. 4) Other suspected risk factors whose significance was not confirmed by multiple conditioned logistic regression analysis were: residence in rural areas, light eyes and blond hair color, extent of the awareness of the "sun x skin cancer" relationship, familial occurrence of skin cancer, excessive exposure to the sun, and freckles appearing in childhood.
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spelling doaj.art-cdf45b7fedc24226865f2537d4c6534d2022-12-22T00:05:57ZengUniversidade de São PauloRevista de Saúde Pública0034-89101518-87871995-01-012912737Risk factors for basal cell carcinoma: a case-control studyMaia MarcusProença Nelson GuimarãesMoraes José Cássio deA controlled trial was performed with the purpose of investigating which factors could be considered of significant risk for the development of basal cell carcinoma. A total of 259 cases of basal cell carcinoma diagnosed from July 1991 to July 1992 were compared with 518 controls matched for age and sex. All subjects in both groups were white. Protocol data were submitted to statistical analysis by the chi-square test and by multiple conditional logistic regression analysis and the following conclusions were reached: 1) light skin color (types I and II of the Fitzpatrick classification), odds ratio of 2.8; outdoor work under constant sunlight, odds ratio of 5.0; the presence of actinic lesions due to exposure to the sun, odds ratio of 4.9, are risk factors perse. 2) Type III skin in the Fitzpatrick classification only represents a risk factor when the patient reports a history of intense sunburns, but not in the absence of such a history. 3) Sunburns per se do not represent a risk factor althorig the point made in item 2 of these conclusions is valid. 4) Other suspected risk factors whose significance was not confirmed by multiple conditioned logistic regression analysis were: residence in rural areas, light eyes and blond hair color, extent of the awareness of the "sun x skin cancer" relationship, familial occurrence of skin cancer, excessive exposure to the sun, and freckles appearing in childhood.http://www.scielosp.org/scielo.php?script=sci_arttext&pid=S0034-89101995000100006Carcinoma, basal cell/epidemiologyRisk factors
spellingShingle Maia Marcus
Proença Nelson Guimarães
Moraes José Cássio de
Risk factors for basal cell carcinoma: a case-control study
Revista de Saúde Pública
Carcinoma, basal cell/epidemiology
Risk factors
title Risk factors for basal cell carcinoma: a case-control study
title_full Risk factors for basal cell carcinoma: a case-control study
title_fullStr Risk factors for basal cell carcinoma: a case-control study
title_full_unstemmed Risk factors for basal cell carcinoma: a case-control study
title_short Risk factors for basal cell carcinoma: a case-control study
title_sort risk factors for basal cell carcinoma a case control study
topic Carcinoma, basal cell/epidemiology
Risk factors
url http://www.scielosp.org/scielo.php?script=sci_arttext&pid=S0034-89101995000100006
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