Treatment of alcohol use disorder in patients with alcohol-associated liver disease: Innovative approaches and a call to action

Abstract Alcohol-associated liver disease is currently the leading cause of liver transplantation and liver deaths both in Europe and the United States. Efficacious treatments exist for alcohol use disorder, but they are seldomly prescribed for patients who need them. Besides, the presence of liver...

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Main Authors: Lamia Y. Haque, Paola Zuluaga, Robert Muga, Daniel Fuster
Format: Article
Language:English
Published: BMC 2024-03-01
Series:Addiction Science & Clinical Practice
Subjects:
Online Access:https://doi.org/10.1186/s13722-024-00448-8
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author Lamia Y. Haque
Paola Zuluaga
Robert Muga
Daniel Fuster
author_facet Lamia Y. Haque
Paola Zuluaga
Robert Muga
Daniel Fuster
author_sort Lamia Y. Haque
collection DOAJ
description Abstract Alcohol-associated liver disease is currently the leading cause of liver transplantation and liver deaths both in Europe and the United States. Efficacious treatments exist for alcohol use disorder, but they are seldomly prescribed for patients who need them. Besides, the presence of liver cirrhosis can complicate pharmacological treatment choices. In this review, we discuss established and innovative treatment strategies to treat unhealthy alcohol use in patients with alcohol-associated liver disease. We also describe the experience of our own institutions, Hospital Universitari Germans Trias i Pujol in Badalona (Spain) and Yale-New Haven Health and Yale Medicine (Connecticut. United States of America).
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spelling doaj.art-cdf54a9de7d24c9fa0dfe68e8e18969f2024-03-24T12:28:41ZengBMCAddiction Science & Clinical Practice1940-06402024-03-0119111110.1186/s13722-024-00448-8Treatment of alcohol use disorder in patients with alcohol-associated liver disease: Innovative approaches and a call to actionLamia Y. Haque0Paola Zuluaga1Robert Muga2Daniel Fuster3Department of Medicine, Digestive Diseases, & Program in Addiction Medicine, Yale School of MedicineDepartment of Internal Medicine, Addiction Unit, Hospital Universitari Germans Trias i Pujol, Universitat Autònoma de BarcelonaDepartment of Internal Medicine, Addiction Unit, Hospital Universitari Germans Trias i Pujol, Universitat Autònoma de BarcelonaDepartment of Internal Medicine, Addiction Unit, Hospital Universitari Germans Trias i Pujol, Universitat Autònoma de BarcelonaAbstract Alcohol-associated liver disease is currently the leading cause of liver transplantation and liver deaths both in Europe and the United States. Efficacious treatments exist for alcohol use disorder, but they are seldomly prescribed for patients who need them. Besides, the presence of liver cirrhosis can complicate pharmacological treatment choices. In this review, we discuss established and innovative treatment strategies to treat unhealthy alcohol use in patients with alcohol-associated liver disease. We also describe the experience of our own institutions, Hospital Universitari Germans Trias i Pujol in Badalona (Spain) and Yale-New Haven Health and Yale Medicine (Connecticut. United States of America).https://doi.org/10.1186/s13722-024-00448-8Alcohol use disorderAlcohol-associated liver diseaseTreatmentAddiction medicineHepatology
spellingShingle Lamia Y. Haque
Paola Zuluaga
Robert Muga
Daniel Fuster
Treatment of alcohol use disorder in patients with alcohol-associated liver disease: Innovative approaches and a call to action
Addiction Science & Clinical Practice
Alcohol use disorder
Alcohol-associated liver disease
Treatment
Addiction medicine
Hepatology
title Treatment of alcohol use disorder in patients with alcohol-associated liver disease: Innovative approaches and a call to action
title_full Treatment of alcohol use disorder in patients with alcohol-associated liver disease: Innovative approaches and a call to action
title_fullStr Treatment of alcohol use disorder in patients with alcohol-associated liver disease: Innovative approaches and a call to action
title_full_unstemmed Treatment of alcohol use disorder in patients with alcohol-associated liver disease: Innovative approaches and a call to action
title_short Treatment of alcohol use disorder in patients with alcohol-associated liver disease: Innovative approaches and a call to action
title_sort treatment of alcohol use disorder in patients with alcohol associated liver disease innovative approaches and a call to action
topic Alcohol use disorder
Alcohol-associated liver disease
Treatment
Addiction medicine
Hepatology
url https://doi.org/10.1186/s13722-024-00448-8
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