Reduction of Dimensionality of a Dynamical Model of Aggressive Tumor Treated by Chemotherapy, Immunotherapy and siRNA Infusion. Part І. Establishment of Time Hierarchy in the Model Dynamics
The Tichonov's theorem for quasi-stationary approximation is considered as a basic approach for reduction of dynamical systems with time hierarchy. On the basis of previously determined parameters, seven ordinary differential equations of the dynamical model of tumor treated by chemotherapy, im...
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| Format: | Article |
| Language: | English |
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Academic Publishing House
2008-12-01
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| Series: | Bioautomation |
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| Online Access: | http://www.clbme.bas.bg/bioautomation/2008/vol_11.1/files/11_3.1.pdf |