Adipose tissue and skeletal muscle wasting precede clinical diagnosis of pancreatic cancer
Abstract Patients with pancreatic cancer commonly develop weight loss and muscle wasting. Whether adipose tissue and skeletal muscle losses begin before diagnosis and the potential utility of such losses for earlier cancer detection are not well understood. We quantify skeletal muscle and adipose ti...
Main Authors: | Ana Babic, Michael H. Rosenthal, Tilak K. Sundaresan, Natalia Khalaf, Valerie Lee, Lauren K. Brais, Maureen Loftus, Leah Caplan, Sarah Denning, Anamol Gurung, Joanna Harrod, Khoschy Schawkat, Chen Yuan, Qiao-Li Wang, Alice A. Lee, Leah H. Biller, Matthew B. Yurgelun, Kimmie Ng, Jonathan A. Nowak, Andrew J. Aguirre, Sangeeta N. Bhatia, Matthew G. Vander Heiden, Stephen K. Van Den Eeden, Bette J. Caan, Brian M. Wolpin |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2023-07-01
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Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-023-40024-3 |
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