IL-34 a Newly Discovered Cytokine
In this study we describe some biological effects of IL-34, a newly discovered cytokine. We show that Il-34 stimulates monocyte cell viability and directly modulates the number and function of monocytes and regulates myeloid cell growth and differentiation. Moreover, since IL-34 in mice is involved...
| Main Authors: | , , , , , , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
SAGE Publishing
2010-05-01
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| Series: | European Journal of Inflammation |
| Online Access: | https://doi.org/10.1177/1721727X1000800202 |
| _version_ | 1818240145700159488 |
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| author | M.L. Castellani A. Anogeianaki P. Felaco E. Toniato M.A. De Lutiis B. Shaik M. Fulcheri J. Vecchiet S. Tetè V. Salini T.C. Theoharides A. Caraffa P. Antinolfi S. Frydas P. Conti C. Cuccurullo C. Ciampoli G. Cerulli |
| author_facet | M.L. Castellani A. Anogeianaki P. Felaco E. Toniato M.A. De Lutiis B. Shaik M. Fulcheri J. Vecchiet S. Tetè V. Salini T.C. Theoharides A. Caraffa P. Antinolfi S. Frydas P. Conti C. Cuccurullo C. Ciampoli G. Cerulli |
| author_sort | M.L. Castellani |
| collection | DOAJ |
| description | In this study we describe some biological effects of IL-34, a newly discovered cytokine. We show that Il-34 stimulates monocyte cell viability and directly modulates the number and function of monocytes and regulates myeloid cell growth and differentiation. Moreover, since IL-34 in mice is involved in osteoporosis, an antagonist of this cytokine could be beneficial for the treatment of this disease. |
| first_indexed | 2024-12-12T13:08:47Z |
| format | Article |
| id | doaj.art-cdfd77cd84f34ffb8c81a90bb4076f4b |
| institution | Directory Open Access Journal |
| issn | 1721-727X |
| language | English |
| last_indexed | 2024-12-12T13:08:47Z |
| publishDate | 2010-05-01 |
| publisher | SAGE Publishing |
| record_format | Article |
| series | European Journal of Inflammation |
| spelling | doaj.art-cdfd77cd84f34ffb8c81a90bb4076f4b2022-12-22T00:23:35ZengSAGE PublishingEuropean Journal of Inflammation1721-727X2010-05-01810.1177/1721727X1000800202IL-34 a Newly Discovered CytokineM.L. CastellaniA. Anogeianaki0P. Felaco1E. ToniatoM.A. De Lutiis2B. Shaik3M. Fulcheri4J. Vecchiet5S. Tetè6V. Salini7T.C. TheoharidesA. Caraffa8P. Antinolfi9S. Frydas10P. ContiC. Cuccurullo11C. Ciampoli12G. Cerulli13 Department of Physiology, Faculty of Medicine, Aristotle University of Thessaloniki, Greece Department of Human Dynamics, University of Chieti, Italy Department of Human Dynamics, University of Chieti, Italy Department of Medicine, Boston University School of Medicine, Boston, MA, USA Department of Clinical Psychology, University of Chieti, Italy Infectious Diseases Division University of Chieti, Italy School of Dentistry, University of Chieti, Italy Orthopaedics Division, University of Chieti Orthopaedics Division, University of Perugia, Perugia, Italy Orthopaedics Division, University of Perugia, Perugia, Italy Parasitology and Parasit Diseases, Faculty of Veterinary Medicine, Aristotle University of Thessaloniki, Greece Division of Medical Pathology, University of Chieti, Italy School of Dentistry, University of Chieti, Italy Orthopaedics Division, University of Perugia, Perugia, ItalyIn this study we describe some biological effects of IL-34, a newly discovered cytokine. We show that Il-34 stimulates monocyte cell viability and directly modulates the number and function of monocytes and regulates myeloid cell growth and differentiation. Moreover, since IL-34 in mice is involved in osteoporosis, an antagonist of this cytokine could be beneficial for the treatment of this disease.https://doi.org/10.1177/1721727X1000800202 |
| spellingShingle | M.L. Castellani A. Anogeianaki P. Felaco E. Toniato M.A. De Lutiis B. Shaik M. Fulcheri J. Vecchiet S. Tetè V. Salini T.C. Theoharides A. Caraffa P. Antinolfi S. Frydas P. Conti C. Cuccurullo C. Ciampoli G. Cerulli IL-34 a Newly Discovered Cytokine European Journal of Inflammation |
| title | IL-34 a Newly Discovered Cytokine |
| title_full | IL-34 a Newly Discovered Cytokine |
| title_fullStr | IL-34 a Newly Discovered Cytokine |
| title_full_unstemmed | IL-34 a Newly Discovered Cytokine |
| title_short | IL-34 a Newly Discovered Cytokine |
| title_sort | il 34 a newly discovered cytokine |
| url | https://doi.org/10.1177/1721727X1000800202 |
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