Disability-adjusted life years of leukemia cancer in children 0-14 year in Asia from 2010 to 2019: a systematic analysis for the global burden of disease study 2019
Objective: Childhood leukemia is the most frequent form of cancer in children. Despite the fact that most children diagnosed with leukemia are cured, many of them experience long-term complications. Materials and Methods: An ecological study was conducted utilizing data related to healthy life year...
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Verduci Editore
2023-12-01
|
| Series: | World Cancer Research Journal |
| Subjects: | |
| Online Access: | https://www.wcrj.net/wp-content/uploads/sites/5/2023/12/e2714.pdf |
| _version_ | 1797374804240629760 |
|---|---|
| author | N. Vahedi H. Hamzehpour A. Ghiasi E. Goodarzi |
| author_facet | N. Vahedi H. Hamzehpour A. Ghiasi E. Goodarzi |
| author_sort | N. Vahedi |
| collection | DOAJ |
| description | Objective: Childhood leukemia is the most frequent form of cancer in children. Despite the fact that most children diagnosed with leukemia are cured, many of them experience long-term complications.
Materials and Methods: An ecological study was conducted utilizing data related to healthy life years lost due to disability (YLDs), years of life lost due to premature death (YLLs), and disability-adjusted life years (DALYs) caused by leukemia cancer (chronic and acute) in children from the Global Burden of Disease (GBD). We used correlation tests at the 0.05 level to examine the correlation between these indicators and the human development index.
Results: The highest DALYs and YLLs in 2010 and 2019 were associated with Low Socio-Demographic Index (SDI) regions, while the highest number of YLDs in 2010 and 2019 were related to High-middle SDI regions in the continent. In Asia, the burden of disease, YLDs and premature death were higher in men than in women from 2010 to 2019. Our results demonstrated a negative and significant correlation between DALY (r=-0.563, p=0.0001) and YLL (r=-0.571, p=0.0001) with the human development index in Asian countries. However, the correlation between the index of YLD (r=- 0.108, p=0.483) and the human development index was not significant.
Conclusions: To reduce the risks associated with leukemia cancer, policymakers should take the necessary measures to improve healthcare systems, promote early diagnosis and treatment, and provide health education to reduce exposure to risk factors related to leukemia cancer. Countries with low human development index have a higher burden of leukemia, which indicates the need for targeted interventions to lower the burden of childhood leukemia in these regions. |
| first_indexed | 2024-03-08T19:11:00Z |
| format | Article |
| id | doaj.art-cdfd927af5fd4d68aee4949497f57b82 |
| institution | Directory Open Access Journal |
| issn | 2372-3416 |
| language | English |
| last_indexed | 2024-03-08T19:11:00Z |
| publishDate | 2023-12-01 |
| publisher | Verduci Editore |
| record_format | Article |
| series | World Cancer Research Journal |
| spelling | doaj.art-cdfd927af5fd4d68aee4949497f57b822023-12-27T15:36:29ZengVerduci EditoreWorld Cancer Research Journal2372-34162023-12-011010.32113/wcrj_202312_27142714Disability-adjusted life years of leukemia cancer in children 0-14 year in Asia from 2010 to 2019: a systematic analysis for the global burden of disease study 2019N. Vahedi0H. Hamzehpour1A. Ghiasi2E. Goodarzi3Department of Nursing, Faculty of Nursing and Midwifery, Tehran Medical Sciences, Islamic Azad University, Tehran, IranDepartment of Nursing, Faculty of Nursing and Midwifery, Tehran Medical Sciences, Islamic Azad University, Tehran, IranSchool of Medicine, Iran University of Medical Sciences, Tehran, IranSocial Determinants of Health Research Center, Lorestan University of Medical Sciences, Khorramabad, IranObjective: Childhood leukemia is the most frequent form of cancer in children. Despite the fact that most children diagnosed with leukemia are cured, many of them experience long-term complications. Materials and Methods: An ecological study was conducted utilizing data related to healthy life years lost due to disability (YLDs), years of life lost due to premature death (YLLs), and disability-adjusted life years (DALYs) caused by leukemia cancer (chronic and acute) in children from the Global Burden of Disease (GBD). We used correlation tests at the 0.05 level to examine the correlation between these indicators and the human development index. Results: The highest DALYs and YLLs in 2010 and 2019 were associated with Low Socio-Demographic Index (SDI) regions, while the highest number of YLDs in 2010 and 2019 were related to High-middle SDI regions in the continent. In Asia, the burden of disease, YLDs and premature death were higher in men than in women from 2010 to 2019. Our results demonstrated a negative and significant correlation between DALY (r=-0.563, p=0.0001) and YLL (r=-0.571, p=0.0001) with the human development index in Asian countries. However, the correlation between the index of YLD (r=- 0.108, p=0.483) and the human development index was not significant. Conclusions: To reduce the risks associated with leukemia cancer, policymakers should take the necessary measures to improve healthcare systems, promote early diagnosis and treatment, and provide health education to reduce exposure to risk factors related to leukemia cancer. Countries with low human development index have a higher burden of leukemia, which indicates the need for targeted interventions to lower the burden of childhood leukemia in these regions.https://www.wcrj.net/wp-content/uploads/sites/5/2023/12/e2714.pdfleukemia cancerchildrenburden of diseaseasiahdi |
| spellingShingle | N. Vahedi H. Hamzehpour A. Ghiasi E. Goodarzi Disability-adjusted life years of leukemia cancer in children 0-14 year in Asia from 2010 to 2019: a systematic analysis for the global burden of disease study 2019 World Cancer Research Journal leukemia cancer children burden of disease asia hdi |
| title | Disability-adjusted life years of leukemia cancer in children 0-14 year in Asia from 2010 to 2019: a systematic analysis for the global burden of disease study 2019 |
| title_full | Disability-adjusted life years of leukemia cancer in children 0-14 year in Asia from 2010 to 2019: a systematic analysis for the global burden of disease study 2019 |
| title_fullStr | Disability-adjusted life years of leukemia cancer in children 0-14 year in Asia from 2010 to 2019: a systematic analysis for the global burden of disease study 2019 |
| title_full_unstemmed | Disability-adjusted life years of leukemia cancer in children 0-14 year in Asia from 2010 to 2019: a systematic analysis for the global burden of disease study 2019 |
| title_short | Disability-adjusted life years of leukemia cancer in children 0-14 year in Asia from 2010 to 2019: a systematic analysis for the global burden of disease study 2019 |
| title_sort | disability adjusted life years of leukemia cancer in children 0 14 year in asia from 2010 to 2019 a systematic analysis for the global burden of disease study 2019 |
| topic | leukemia cancer children burden of disease asia hdi |
| url | https://www.wcrj.net/wp-content/uploads/sites/5/2023/12/e2714.pdf |
| work_keys_str_mv | AT nvahedi disabilityadjustedlifeyearsofleukemiacancerinchildren014yearinasiafrom2010to2019asystematicanalysisfortheglobalburdenofdiseasestudy2019 AT hhamzehpour disabilityadjustedlifeyearsofleukemiacancerinchildren014yearinasiafrom2010to2019asystematicanalysisfortheglobalburdenofdiseasestudy2019 AT aghiasi disabilityadjustedlifeyearsofleukemiacancerinchildren014yearinasiafrom2010to2019asystematicanalysisfortheglobalburdenofdiseasestudy2019 AT egoodarzi disabilityadjustedlifeyearsofleukemiacancerinchildren014yearinasiafrom2010to2019asystematicanalysisfortheglobalburdenofdiseasestudy2019 |