Effect of intravitreal Conbercept on wet age-related macular degeneration and polypoidal choroidal vasculopathy
AIM:To investigate the clinical effect of intravitreal conbercept on wet age-related macular degeneration(wAMD)and polypoidal choroidal vasculopathy(PCV). <p>METHODS: Sixteen patients(16 eyes)with wAMD and 5 patients(5 eyes)with PCV, both clinical diagnosed, were enrolled. All patients were tr...
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| Format: | Article |
| Language: | English |
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Press of International Journal of Ophthalmology (IJO PRESS)
2015-11-01
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| Series: | Guoji Yanke Zazhi |
| Subjects: | |
| Online Access: | http://ies.ijo.cn/cn_publish/2015/11/201511048.pdf |
| _version_ | 1819293698282749952 |
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| author | Ying-Chun Li Ying-Chuan Fan |
| author_facet | Ying-Chun Li Ying-Chuan Fan |
| author_sort | Ying-Chun Li |
| collection | DOAJ |
| description | AIM:To investigate the clinical effect of intravitreal conbercept on wet age-related macular degeneration(wAMD)and polypoidal choroidal vasculopathy(PCV). <p>METHODS: Sixteen patients(16 eyes)with wAMD and 5 patients(5 eyes)with PCV, both clinical diagnosed, were enrolled. All patients were treated with intravitreous conbercept.Additional treatments were administered if needed. Best corrected visual acuity(BCVA), central retinal thickness(CRT)and choroidal thickness(CT)were measured periodically. <p>RESULTS:The mean injection times at 6mo was 2.93±0.27. The mean BCVAs were 0.87±0.52 at baseline and 0.74±0.43 at 6mo, which the difference was not statistically significant. The mean CRT significantly improved from 352.24±131.82 to 251.73±69.41μm at 6mo(<i>P</i><0.01). The mean CT reduced from 331.93±115.35 to 304.72±104.59μm(<i>P</i><0.05). <p>CONCLUSION:Intravitreal conbercept can keep the visual acuity stable, reduce the retinal thickness and is safe on treating wAMD and PCV. |
| first_indexed | 2024-12-24T04:14:34Z |
| format | Article |
| id | doaj.art-cdfe3850ed25411cb8c34ef4e90bf0d8 |
| institution | Directory Open Access Journal |
| issn | 1672-5123 1672-5123 |
| language | English |
| last_indexed | 2024-12-24T04:14:34Z |
| publishDate | 2015-11-01 |
| publisher | Press of International Journal of Ophthalmology (IJO PRESS) |
| record_format | Article |
| series | Guoji Yanke Zazhi |
| spelling | doaj.art-cdfe3850ed25411cb8c34ef4e90bf0d82022-12-21T17:15:59ZengPress of International Journal of Ophthalmology (IJO PRESS)Guoji Yanke Zazhi1672-51231672-51232015-11-0115112009201110.3980/j.issn.1672-5123.2015.11.48Effect of intravitreal Conbercept on wet age-related macular degeneration and polypoidal choroidal vasculopathyYing-Chun Li0Ying-Chuan Fan1Kangqiao Eye Hospital Affiliated to Chengdu Medical College of Aier Eye Group, Chengdu 614001, Sichuan Province, ChinaKangqiao Eye Hospital Affiliated to Chengdu Medical College of Aier Eye Group, Chengdu 614001, Sichuan Province, China; Department of Ophthalmology, Sichuan Academy of Medical Sciences & Sichuan Provincial People's Hospital, Chengdu 610072, ChinaAIM:To investigate the clinical effect of intravitreal conbercept on wet age-related macular degeneration(wAMD)and polypoidal choroidal vasculopathy(PCV). <p>METHODS: Sixteen patients(16 eyes)with wAMD and 5 patients(5 eyes)with PCV, both clinical diagnosed, were enrolled. All patients were treated with intravitreous conbercept.Additional treatments were administered if needed. Best corrected visual acuity(BCVA), central retinal thickness(CRT)and choroidal thickness(CT)were measured periodically. <p>RESULTS:The mean injection times at 6mo was 2.93±0.27. The mean BCVAs were 0.87±0.52 at baseline and 0.74±0.43 at 6mo, which the difference was not statistically significant. The mean CRT significantly improved from 352.24±131.82 to 251.73±69.41μm at 6mo(<i>P</i><0.01). The mean CT reduced from 331.93±115.35 to 304.72±104.59μm(<i>P</i><0.05). <p>CONCLUSION:Intravitreal conbercept can keep the visual acuity stable, reduce the retinal thickness and is safe on treating wAMD and PCV.http://ies.ijo.cn/cn_publish/2015/11/201511048.pdfage-related macular degenerationpolypoidal choroidal vasculopathyconbercept |
| spellingShingle | Ying-Chun Li Ying-Chuan Fan Effect of intravitreal Conbercept on wet age-related macular degeneration and polypoidal choroidal vasculopathy Guoji Yanke Zazhi age-related macular degeneration polypoidal choroidal vasculopathy conbercept |
| title | Effect of intravitreal Conbercept on wet age-related macular degeneration and polypoidal choroidal vasculopathy |
| title_full | Effect of intravitreal Conbercept on wet age-related macular degeneration and polypoidal choroidal vasculopathy |
| title_fullStr | Effect of intravitreal Conbercept on wet age-related macular degeneration and polypoidal choroidal vasculopathy |
| title_full_unstemmed | Effect of intravitreal Conbercept on wet age-related macular degeneration and polypoidal choroidal vasculopathy |
| title_short | Effect of intravitreal Conbercept on wet age-related macular degeneration and polypoidal choroidal vasculopathy |
| title_sort | effect of intravitreal conbercept on wet age related macular degeneration and polypoidal choroidal vasculopathy |
| topic | age-related macular degeneration polypoidal choroidal vasculopathy conbercept |
| url | http://ies.ijo.cn/cn_publish/2015/11/201511048.pdf |
| work_keys_str_mv | AT yingchunli effectofintravitrealconberceptonwetagerelatedmaculardegenerationandpolypoidalchoroidalvasculopathy AT yingchuanfan effectofintravitrealconberceptonwetagerelatedmaculardegenerationandpolypoidalchoroidalvasculopathy |