Association between wine consumption and cancer: a systematic review and meta-analysis
BackgroundAlcohol consumption is related to the risk of developing different types of cancer. However, unlike other alcoholic beverages, moderate wine drinking has demonstrated a protective effect on the risk of developing several types of cancer.ObjectiveTo analyze the association between wine cons...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2023-09-01
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| Series: | Frontiers in Nutrition |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fnut.2023.1197745/full |
| _version_ | 1797693924752490496 |
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| author | Maribel Lucerón-Lucas-Torres Iván Cavero-Redondo Iván Cavero-Redondo Vicente Martínez-Vizcaíno Vicente Martínez-Vizcaíno Bruno Bizzozero-Peroni Bruno Bizzozero-Peroni Carlos Pascual-Morena Celia Álvarez-Bueno Celia Álvarez-Bueno |
| author_facet | Maribel Lucerón-Lucas-Torres Iván Cavero-Redondo Iván Cavero-Redondo Vicente Martínez-Vizcaíno Vicente Martínez-Vizcaíno Bruno Bizzozero-Peroni Bruno Bizzozero-Peroni Carlos Pascual-Morena Celia Álvarez-Bueno Celia Álvarez-Bueno |
| author_sort | Maribel Lucerón-Lucas-Torres |
| collection | DOAJ |
| description | BackgroundAlcohol consumption is related to the risk of developing different types of cancer. However, unlike other alcoholic beverages, moderate wine drinking has demonstrated a protective effect on the risk of developing several types of cancer.ObjectiveTo analyze the association between wine consumption and the risk of developing cancer.MethodsWe searched the MEDLINE (through PubMed), Scopus, Cochrane, and Web of Science databases to conduct this systematic review and meta-analysis. Pooled relative risks (RRs) were calculated using the DerSimonian and Laird methods. I2 was used to evaluate inconsistency, the τ2 test was used to assess heterogeneity, and The Newcastle-Ottawa Quality Assessment Scale were applied to evaluate the risk of bias. This study was previously registered in PROSPERO, with the registration number CRD42022315864.ResultsSeventy-three studies were included in the systematic review, and 26 were included in the meta-analysis. The pooled RR for the effect of wine consumption on the risk of gynecological cancers was 1.03 (95% CI: 0.99, 1.08), that for colorectal cancer was 0.92 (95% CI: 0.82, 1.03), and that for renal cancer was 0.92 (95% CI: 0.81, 1.04). In general, the heterogeneity was substantial.ConclusionThe study findings reveal no association between wine consumption and the risk of developing any type of cancer. Moreover, wine drinking demonstrated a protective trend regarding the risk of developing pancreatic, skin, lung, and brain cancer as well as cancer in general.Systematic review registrationhttps://www.crd.york.ac.uk/prospero/display_record.php?ID=CRD42022315864, identifier CRD42022315864 (PROSPERO). |
| first_indexed | 2024-03-12T02:50:41Z |
| format | Article |
| id | doaj.art-ce0324bf7c0b48dbbf59b540e4428ae6 |
| institution | Directory Open Access Journal |
| issn | 2296-861X |
| language | English |
| last_indexed | 2024-03-12T02:50:41Z |
| publishDate | 2023-09-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Nutrition |
| spelling | doaj.art-ce0324bf7c0b48dbbf59b540e4428ae62023-09-04T05:07:02ZengFrontiers Media S.A.Frontiers in Nutrition2296-861X2023-09-011010.3389/fnut.2023.11977451197745Association between wine consumption and cancer: a systematic review and meta-analysisMaribel Lucerón-Lucas-Torres0Iván Cavero-Redondo1Iván Cavero-Redondo2Vicente Martínez-Vizcaíno3Vicente Martínez-Vizcaíno4Bruno Bizzozero-Peroni5Bruno Bizzozero-Peroni6Carlos Pascual-Morena7Celia Álvarez-Bueno8Celia Álvarez-Bueno9Health and Social Research Center, Universidad de Castilla-La Mancha, Cuenca, SpainHealth and Social Research Center, Universidad de Castilla-La Mancha, Cuenca, SpainFacultad de Ciencias de la Salud, Universidad Autónoma de Chile, Talca, ChileHealth and Social Research Center, Universidad de Castilla-La Mancha, Cuenca, SpainFacultad de Ciencias de la Salud, Universidad Autónoma de Chile, Talca, ChileHealth and Social Research Center, Universidad de Castilla-La Mancha, Cuenca, SpainHigher Institute of Physical Education, Universidad de la República, Rivera, UruguayHealth and Social Research Center, Universidad de Castilla-La Mancha, Cuenca, SpainHealth and Social Research Center, Universidad de Castilla-La Mancha, Cuenca, SpainUniversidad Politécnica y Artística del Paraguay, Asunción, ParaguayBackgroundAlcohol consumption is related to the risk of developing different types of cancer. However, unlike other alcoholic beverages, moderate wine drinking has demonstrated a protective effect on the risk of developing several types of cancer.ObjectiveTo analyze the association between wine consumption and the risk of developing cancer.MethodsWe searched the MEDLINE (through PubMed), Scopus, Cochrane, and Web of Science databases to conduct this systematic review and meta-analysis. Pooled relative risks (RRs) were calculated using the DerSimonian and Laird methods. I2 was used to evaluate inconsistency, the τ2 test was used to assess heterogeneity, and The Newcastle-Ottawa Quality Assessment Scale were applied to evaluate the risk of bias. This study was previously registered in PROSPERO, with the registration number CRD42022315864.ResultsSeventy-three studies were included in the systematic review, and 26 were included in the meta-analysis. The pooled RR for the effect of wine consumption on the risk of gynecological cancers was 1.03 (95% CI: 0.99, 1.08), that for colorectal cancer was 0.92 (95% CI: 0.82, 1.03), and that for renal cancer was 0.92 (95% CI: 0.81, 1.04). In general, the heterogeneity was substantial.ConclusionThe study findings reveal no association between wine consumption and the risk of developing any type of cancer. Moreover, wine drinking demonstrated a protective trend regarding the risk of developing pancreatic, skin, lung, and brain cancer as well as cancer in general.Systematic review registrationhttps://www.crd.york.ac.uk/prospero/display_record.php?ID=CRD42022315864, identifier CRD42022315864 (PROSPERO).https://www.frontiersin.org/articles/10.3389/fnut.2023.1197745/fullcancerwineadult peoplealcohol consumptionsystematic review and meta-analysis |
| spellingShingle | Maribel Lucerón-Lucas-Torres Iván Cavero-Redondo Iván Cavero-Redondo Vicente Martínez-Vizcaíno Vicente Martínez-Vizcaíno Bruno Bizzozero-Peroni Bruno Bizzozero-Peroni Carlos Pascual-Morena Celia Álvarez-Bueno Celia Álvarez-Bueno Association between wine consumption and cancer: a systematic review and meta-analysis Frontiers in Nutrition cancer wine adult people alcohol consumption systematic review and meta-analysis |
| title | Association between wine consumption and cancer: a systematic review and meta-analysis |
| title_full | Association between wine consumption and cancer: a systematic review and meta-analysis |
| title_fullStr | Association between wine consumption and cancer: a systematic review and meta-analysis |
| title_full_unstemmed | Association between wine consumption and cancer: a systematic review and meta-analysis |
| title_short | Association between wine consumption and cancer: a systematic review and meta-analysis |
| title_sort | association between wine consumption and cancer a systematic review and meta analysis |
| topic | cancer wine adult people alcohol consumption systematic review and meta-analysis |
| url | https://www.frontiersin.org/articles/10.3389/fnut.2023.1197745/full |
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