Risk of secondary malignant neoplasms in children following proton therapy vs. photon therapy for primary CNS tumors: A systematic review and meta-analysis

Risk of secondary malignant neoplasms in children following proton therapy vs. photon therapy for primary CNS tumors: A systematic review and meta-analysis

BackgroundCentral nervous system tumors are now the most common primary neoplasms seen in children, and radiation therapy is a key component in management. Secondary malignant neoplasms (SMNs) are rare, but dreaded complications. Proton beam therapy (PBT) can potentially minimize the risk of SMNs co...

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Bibliographic Details
Main Authors: Rituraj Upadhyay, Divya Yadav, Bhanu P. Venkatesulu, Raj Singh, Sujith Baliga, Raju R. Raval, Margot A. Lazow, Ralph Salloum, Maryam Fouladi, Elaine R. Mardis, Nicholas G. Zaorsky, Daniel M. Trifiletti, Arnold C. Paulino, Joshua D. Palmer
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-08-01
Series:Frontiers in Oncology
Subjects:
secondary Malignant Neoplasms after proton therapy vs photon therapy secondary cancer
proton therapy
CNS radiation
pediatric cancer
photon
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2022.893855/full

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