Intestinal perforation complicating type II enteropathy-associated T-cell lymphoma

Type II enteropathy-associated T-cell lymphoma (Type II EATL) is only rarely reported in Asia, especially in Taiwan and is known to be associated with a high bowel perforation rate. We described a case of Type II EATL with fatal perforation of the small intestine during his first cycle of chemothera...

Full description

Bibliographic Details
Main Authors: Fu-Chiang Yeh, Hong-Wei Gao, Sheng-Der Hsu, Jia-Hong Chen, Woei-Yau Kao
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2014-01-01
Series:Journal of Medical Sciences
Subjects:
Online Access:http://jms.ndmctsgh.edu.tw/article.asp?issn=1011-4564;year=2014;volume=34;issue=3;spage=140;epage=144;aulast=Yeh
_version_ 1828465135315845120
author Fu-Chiang Yeh
Hong-Wei Gao
Sheng-Der Hsu
Jia-Hong Chen
Woei-Yau Kao
author_facet Fu-Chiang Yeh
Hong-Wei Gao
Sheng-Der Hsu
Jia-Hong Chen
Woei-Yau Kao
author_sort Fu-Chiang Yeh
collection DOAJ
description Type II enteropathy-associated T-cell lymphoma (Type II EATL) is only rarely reported in Asia, especially in Taiwan and is known to be associated with a high bowel perforation rate. We described a case of Type II EATL with fatal perforation of the small intestine during his first cycle of chemotherapy. Conventional treatment for enteropathy-associated T-cell lymphoma consists of combination chemotherapy used for aggressive T-cell lymphoma (e.g., cyclophosphamide, adriamycin, vincristine, prednisone). Perforation of intestine often occurs at the time of diagnosis or in the early days of the first cycle of chemotherapy in these patients. To rescue and treat patient promptly, intestinal perforation should always be kept in mind as a differential diagnosis of acute abdominal pain in these patients. This case report highlights the potential pitfall in managing patients with gastrointestinal lymphoma and the need for maintaining a low threshold for prechemotherapy surgical intervention in patients diagnosed with type II EATL.
first_indexed 2024-12-11T03:26:10Z
format Article
id doaj.art-ce09052434d44fe8a89ad3d4a48b8298
institution Directory Open Access Journal
issn 1011-4564
language English
last_indexed 2024-12-11T03:26:10Z
publishDate 2014-01-01
publisher Wolters Kluwer Medknow Publications
record_format Article
series Journal of Medical Sciences
spelling doaj.art-ce09052434d44fe8a89ad3d4a48b82982022-12-22T01:22:30ZengWolters Kluwer Medknow PublicationsJournal of Medical Sciences1011-45642014-01-0134314014410.4103/1011-4564.134416Intestinal perforation complicating type II enteropathy-associated T-cell lymphomaFu-Chiang YehHong-Wei GaoSheng-Der HsuJia-Hong ChenWoei-Yau KaoType II enteropathy-associated T-cell lymphoma (Type II EATL) is only rarely reported in Asia, especially in Taiwan and is known to be associated with a high bowel perforation rate. We described a case of Type II EATL with fatal perforation of the small intestine during his first cycle of chemotherapy. Conventional treatment for enteropathy-associated T-cell lymphoma consists of combination chemotherapy used for aggressive T-cell lymphoma (e.g., cyclophosphamide, adriamycin, vincristine, prednisone). Perforation of intestine often occurs at the time of diagnosis or in the early days of the first cycle of chemotherapy in these patients. To rescue and treat patient promptly, intestinal perforation should always be kept in mind as a differential diagnosis of acute abdominal pain in these patients. This case report highlights the potential pitfall in managing patients with gastrointestinal lymphoma and the need for maintaining a low threshold for prechemotherapy surgical intervention in patients diagnosed with type II EATL.http://jms.ndmctsgh.edu.tw/article.asp?issn=1011-4564;year=2014;volume=34;issue=3;spage=140;epage=144;aulast=YehT-cell lymphomaenteropathyintestinal perforation
spellingShingle Fu-Chiang Yeh
Hong-Wei Gao
Sheng-Der Hsu
Jia-Hong Chen
Woei-Yau Kao
Intestinal perforation complicating type II enteropathy-associated T-cell lymphoma
Journal of Medical Sciences
T-cell lymphoma
enteropathy
intestinal perforation
title Intestinal perforation complicating type II enteropathy-associated T-cell lymphoma
title_full Intestinal perforation complicating type II enteropathy-associated T-cell lymphoma
title_fullStr Intestinal perforation complicating type II enteropathy-associated T-cell lymphoma
title_full_unstemmed Intestinal perforation complicating type II enteropathy-associated T-cell lymphoma
title_short Intestinal perforation complicating type II enteropathy-associated T-cell lymphoma
title_sort intestinal perforation complicating type ii enteropathy associated t cell lymphoma
topic T-cell lymphoma
enteropathy
intestinal perforation
url http://jms.ndmctsgh.edu.tw/article.asp?issn=1011-4564;year=2014;volume=34;issue=3;spage=140;epage=144;aulast=Yeh
work_keys_str_mv AT fuchiangyeh intestinalperforationcomplicatingtypeiienteropathyassociatedtcelllymphoma
AT hongweigao intestinalperforationcomplicatingtypeiienteropathyassociatedtcelllymphoma
AT shengderhsu intestinalperforationcomplicatingtypeiienteropathyassociatedtcelllymphoma
AT jiahongchen intestinalperforationcomplicatingtypeiienteropathyassociatedtcelllymphoma
AT woeiyaukao intestinalperforationcomplicatingtypeiienteropathyassociatedtcelllymphoma