Mutagenesis-Based Characterization and Improvement of a Novel Inclusion Body Tag

Mutagenesis-Based Characterization and Improvement of a Novel Inclusion Body Tag

Whereas, bacterial inclusion bodies (IBs) for long were regarded as undesirable aggregates emerging during recombinant protein production, they currently receive attention as promising nanoparticulate biomaterials with diverse applications in biotechnology and biomedicine. We previously identified s...

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Bibliographic Details
Main Authors: Wouter S. P. Jong, Corinne M. ten Hagen-Jongman, David Vikström, Wendy Dontje, Abdallah M. Abdallah, Jan-Willem de Gier, Wilbert Bitter, Joen Luirink
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-01-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
inclusion bodies
fusion tag
insoluble expression
protein aggregation
heterologous protein production
signal peptide
Online Access:https://www.frontiersin.org/article/10.3389/fbioe.2019.00442/full

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