The levels and trends of cancer incidence in the elderly population at national and sub‐national scales in Iran from 1990 to 2016
Abstract Background Cancer is most commonly associated with aging. It is necessary to gain a better understanding of cancer's trend and distribution among elderlies and provide comprehensive cancer care for this population. Aims The aim of the current study was to show the trends in cancer inci...
| Main Authors: | , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2024-01-01
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| Series: | Cancer Reports |
| Subjects: | |
| Online Access: | https://doi.org/10.1002/cnr2.1937 |
| _version_ | 1827372957081534464 |
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| author | Zahra Shokri Varniab Sahar Saeedi Moghaddam Ashkan Pourabhari Langroudi Sina Azadnajafabad Seyede Salehe Mortazavi Ali Sheidaei Kimiya Gohari Yosef Farzi Zeinab Shirzad Moghaddam Hanye Sohrabi Mohsen Shati |
| author_facet | Zahra Shokri Varniab Sahar Saeedi Moghaddam Ashkan Pourabhari Langroudi Sina Azadnajafabad Seyede Salehe Mortazavi Ali Sheidaei Kimiya Gohari Yosef Farzi Zeinab Shirzad Moghaddam Hanye Sohrabi Mohsen Shati |
| author_sort | Zahra Shokri Varniab |
| collection | DOAJ |
| description | Abstract Background Cancer is most commonly associated with aging. It is necessary to gain a better understanding of cancer's trend and distribution among elderlies and provide comprehensive cancer care for this population. Aims The aim of the current study was to show the trends in cancer incidence focusing on the population aged 60+ from 1990 to 2016 in Iran. Material and Results We used the dataset of the Iran Cancer Registry to estimate cancer incidences by sex, age, province, and year. In order to account for incomplete data we used a two‐stage spatiotemporal model along with random intercept mixed effect models. We calculated annual age‐standardized incidence rates (ASIRs) for age groups 60+ and 5‐interval age groups. There was an increasing trend of 25.3% to 936.9% (95% uncertainty interval: 769.6–1141.8) in ASIR in the elderly in 2016. ASIR of all cancers were 889.7 (731.3–1083.6) in women and 988.1 (811.1–1205) in men in 2016, per 100 000 respectively, which had an increasing trend comparing 1990. Skin, breast, and stomach cancers in women and prostate, skin, and stomach cancers in men were the most common types in 2016. All the most incident cancer subtypes underwent an increasing trend in both sexes, except for the bladder, esophageal, and skin cancers which almost had a similar level in 1990 and 2016. Most provinces had an increasing trend in ASIR in all cancers combined from 1990 to 2016 except Zanjan with a decreasing trend. Conclusion Regarding the persistent increasing trend of most elderly cancers' incidence, this is crucial for policymakers to establish preventive plans, determine proper resource allocation, and develop specific treatments for elderly cancer patients. |
| first_indexed | 2024-03-08T11:08:48Z |
| format | Article |
| id | doaj.art-ce0d5e1cf57e4288b77f105ee32186ed |
| institution | Directory Open Access Journal |
| issn | 2573-8348 |
| language | English |
| last_indexed | 2024-03-08T11:08:48Z |
| publishDate | 2024-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Cancer Reports |
| spelling | doaj.art-ce0d5e1cf57e4288b77f105ee32186ed2024-01-26T14:25:01ZengWileyCancer Reports2573-83482024-01-0171n/an/a10.1002/cnr2.1937The levels and trends of cancer incidence in the elderly population at national and sub‐national scales in Iran from 1990 to 2016Zahra Shokri Varniab0Sahar Saeedi Moghaddam1Ashkan Pourabhari Langroudi2Sina Azadnajafabad3Seyede Salehe Mortazavi4Ali Sheidaei5Kimiya Gohari6Yosef Farzi7Zeinab Shirzad Moghaddam8Hanye Sohrabi9Mohsen Shati10Non‐Communicable Diseases Research Center, Endocrinology and Metabolism Population Sciences Institute Tehran University of Medical Sciences Tehran IranNon‐Communicable Diseases Research Center, Endocrinology and Metabolism Population Sciences Institute Tehran University of Medical Sciences Tehran IranNon‐Communicable Diseases Research Center, Endocrinology and Metabolism Population Sciences Institute Tehran University of Medical Sciences Tehran IranNon‐Communicable Diseases Research Center, Endocrinology and Metabolism Population Sciences Institute Tehran University of Medical Sciences Tehran IranGeriatric Mental Health Research Center, School of Behavioral Sciences and Mental Health (Tehran Institute of Psychiatry) Iran University of Medical Sciences Tehran IranNon‐Communicable Diseases Research Center, Endocrinology and Metabolism Population Sciences Institute Tehran University of Medical Sciences Tehran IranNon‐Communicable Diseases Research Center, Endocrinology and Metabolism Population Sciences Institute Tehran University of Medical Sciences Tehran IranNon‐Communicable Diseases Research Center, Endocrinology and Metabolism Population Sciences Institute Tehran University of Medical Sciences Tehran IranNon‐Communicable Diseases Research Center, Endocrinology and Metabolism Population Sciences Institute Tehran University of Medical Sciences Tehran IranNon‐Communicable Diseases Research Center, Endocrinology and Metabolism Population Sciences Institute Tehran University of Medical Sciences Tehran IranMental Health Research Center, Department of Epidemiology, Psychosocial Health Research Institute Iran University of Medical Sciences Tehran IranAbstract Background Cancer is most commonly associated with aging. It is necessary to gain a better understanding of cancer's trend and distribution among elderlies and provide comprehensive cancer care for this population. Aims The aim of the current study was to show the trends in cancer incidence focusing on the population aged 60+ from 1990 to 2016 in Iran. Material and Results We used the dataset of the Iran Cancer Registry to estimate cancer incidences by sex, age, province, and year. In order to account for incomplete data we used a two‐stage spatiotemporal model along with random intercept mixed effect models. We calculated annual age‐standardized incidence rates (ASIRs) for age groups 60+ and 5‐interval age groups. There was an increasing trend of 25.3% to 936.9% (95% uncertainty interval: 769.6–1141.8) in ASIR in the elderly in 2016. ASIR of all cancers were 889.7 (731.3–1083.6) in women and 988.1 (811.1–1205) in men in 2016, per 100 000 respectively, which had an increasing trend comparing 1990. Skin, breast, and stomach cancers in women and prostate, skin, and stomach cancers in men were the most common types in 2016. All the most incident cancer subtypes underwent an increasing trend in both sexes, except for the bladder, esophageal, and skin cancers which almost had a similar level in 1990 and 2016. Most provinces had an increasing trend in ASIR in all cancers combined from 1990 to 2016 except Zanjan with a decreasing trend. Conclusion Regarding the persistent increasing trend of most elderly cancers' incidence, this is crucial for policymakers to establish preventive plans, determine proper resource allocation, and develop specific treatments for elderly cancer patients.https://doi.org/10.1002/cnr2.1937elderlyepidemiologygeriatricsincidenceneoplasms |
| spellingShingle | Zahra Shokri Varniab Sahar Saeedi Moghaddam Ashkan Pourabhari Langroudi Sina Azadnajafabad Seyede Salehe Mortazavi Ali Sheidaei Kimiya Gohari Yosef Farzi Zeinab Shirzad Moghaddam Hanye Sohrabi Mohsen Shati The levels and trends of cancer incidence in the elderly population at national and sub‐national scales in Iran from 1990 to 2016 Cancer Reports elderly epidemiology geriatrics incidence neoplasms |
| title | The levels and trends of cancer incidence in the elderly population at national and sub‐national scales in Iran from 1990 to 2016 |
| title_full | The levels and trends of cancer incidence in the elderly population at national and sub‐national scales in Iran from 1990 to 2016 |
| title_fullStr | The levels and trends of cancer incidence in the elderly population at national and sub‐national scales in Iran from 1990 to 2016 |
| title_full_unstemmed | The levels and trends of cancer incidence in the elderly population at national and sub‐national scales in Iran from 1990 to 2016 |
| title_short | The levels and trends of cancer incidence in the elderly population at national and sub‐national scales in Iran from 1990 to 2016 |
| title_sort | levels and trends of cancer incidence in the elderly population at national and sub national scales in iran from 1990 to 2016 |
| topic | elderly epidemiology geriatrics incidence neoplasms |
| url | https://doi.org/10.1002/cnr2.1937 |
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