Opposing Actions of TLR2 and TLR4 in Adipocyte Differentiation and Mature-Onset Obesity

Opposing Actions of TLR2 and TLR4 in Adipocyte Differentiation and Mature-Onset Obesity

Understanding the signaling cascades that govern adipocyte metabolism and differentiation is necessary for the development of therapies for obesity. Toll-like receptors (TLRs) are key mediators in adipogenesis, but their specific role is not completely understood. In this study, siRNA knockdown of &...

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Bibliographic Details
Main Authors: Natalia Cuesta, Sonia Fernández-Veledo, Carmen Punzón, Cristóbal Moreno, Beatriz Barrocal, Vinatha Sreeramkumar, Manuel Desco, Manuel Fresno
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:International Journal of Molecular Sciences
Subjects:
adipocyte differentiation
TLR2
TLR4
obesity
Online Access:https://www.mdpi.com/1422-0067/23/24/15682

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