Angiotensin II and Angiotensin Receptors 1 and 2—Multifunctional System in Cells Biology, What Do We Know?
For years, the renin-angiotensin system (RAS) has been perceived as a system whose role is to primarily modulate the functioning of the cardiovascular system. Years of research into the role of RAS have provided the necessary data to confirm that the role of RAS is very complex and not limited to th...
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| Format: | Article |
| Language: | English |
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MDPI AG
2021-02-01
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| Series: | Cells |
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| Online Access: | https://www.mdpi.com/2073-4409/10/2/381 |
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| author | Maksymilian Ziaja Kinga Anna Urbanek Karolina Kowalska Agnieszka Wanda Piastowska-Ciesielska |
| author_facet | Maksymilian Ziaja Kinga Anna Urbanek Karolina Kowalska Agnieszka Wanda Piastowska-Ciesielska |
| author_sort | Maksymilian Ziaja |
| collection | DOAJ |
| description | For years, the renin-angiotensin system (RAS) has been perceived as a system whose role is to primarily modulate the functioning of the cardiovascular system. Years of research into the role of RAS have provided the necessary data to confirm that the role of RAS is very complex and not limited to the cardiovascular system. The presence of individual elements of the renin-angiotensin (RA) system allows to control many processes, ranging from the memorization to pro-cancer processes. Maintaining the proportions between the individual axes of the RA system allows for achieving a balance, often called homeostasis. Thus, any disturbance in the expression or activity of individual RAS elements leads to pathophysiological processes. |
| first_indexed | 2024-03-09T00:56:59Z |
| format | Article |
| id | doaj.art-ce0e5e6cc07245a2b9415bb4da824900 |
| institution | Directory Open Access Journal |
| issn | 2073-4409 |
| language | English |
| last_indexed | 2024-03-09T00:56:59Z |
| publishDate | 2021-02-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Cells |
| spelling | doaj.art-ce0e5e6cc07245a2b9415bb4da8249002023-12-11T16:51:24ZengMDPI AGCells2073-44092021-02-0110238110.3390/cells10020381Angiotensin II and Angiotensin Receptors 1 and 2—Multifunctional System in Cells Biology, What Do We Know?Maksymilian Ziaja0Kinga Anna Urbanek1Karolina Kowalska2Agnieszka Wanda Piastowska-Ciesielska3Department of Cell Culture and Genomic Analysis, Medical University of Lodz, Zeligowskiego 7/9, 90-752 Lodz, PolandDepartment of Cell Culture and Genomic Analysis, Medical University of Lodz, Zeligowskiego 7/9, 90-752 Lodz, PolandDepartment of Cell Culture and Genomic Analysis, Medical University of Lodz, Zeligowskiego 7/9, 90-752 Lodz, PolandDepartment of Cell Culture and Genomic Analysis, Medical University of Lodz, Zeligowskiego 7/9, 90-752 Lodz, PolandFor years, the renin-angiotensin system (RAS) has been perceived as a system whose role is to primarily modulate the functioning of the cardiovascular system. Years of research into the role of RAS have provided the necessary data to confirm that the role of RAS is very complex and not limited to the cardiovascular system. The presence of individual elements of the renin-angiotensin (RA) system allows to control many processes, ranging from the memorization to pro-cancer processes. Maintaining the proportions between the individual axes of the RA system allows for achieving a balance, often called homeostasis. Thus, any disturbance in the expression or activity of individual RAS elements leads to pathophysiological processes.https://www.mdpi.com/2073-4409/10/2/381angiotensinrenin-angiotensin systemcancerpathophysiology |
| spellingShingle | Maksymilian Ziaja Kinga Anna Urbanek Karolina Kowalska Agnieszka Wanda Piastowska-Ciesielska Angiotensin II and Angiotensin Receptors 1 and 2—Multifunctional System in Cells Biology, What Do We Know? Cells angiotensin renin-angiotensin system cancer pathophysiology |
| title | Angiotensin II and Angiotensin Receptors 1 and 2—Multifunctional System in Cells Biology, What Do We Know? |
| title_full | Angiotensin II and Angiotensin Receptors 1 and 2—Multifunctional System in Cells Biology, What Do We Know? |
| title_fullStr | Angiotensin II and Angiotensin Receptors 1 and 2—Multifunctional System in Cells Biology, What Do We Know? |
| title_full_unstemmed | Angiotensin II and Angiotensin Receptors 1 and 2—Multifunctional System in Cells Biology, What Do We Know? |
| title_short | Angiotensin II and Angiotensin Receptors 1 and 2—Multifunctional System in Cells Biology, What Do We Know? |
| title_sort | angiotensin ii and angiotensin receptors 1 and 2 multifunctional system in cells biology what do we know |
| topic | angiotensin renin-angiotensin system cancer pathophysiology |
| url | https://www.mdpi.com/2073-4409/10/2/381 |
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