A Case of Ofuji Disease Successfully Treated with the Combination of Low-Dose Indomethacin and Topical Tacrolimus
Eosinophilic pustular folliculitis (EPF) (Ofuji disease) is a chronic, noninfectious pruritic cutaneous disorder of unknown etiology. No official guidelines are available for its treatment. Herein we present the case of a 59-year-old Caucasian man admitted to our outpatient clinic due to a generaliz...
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| Format: | Article |
| Language: | English |
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Karger Publishers
2020-08-01
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| Series: | Case Reports in Dermatology |
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| Online Access: | https://www.karger.com/Article/FullText/509176 |
| _version_ | 1819262810491715584 |
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| author | Claudio Marasca Angelo Ruggiero Gabriella Fabbrocini Matteo Megna |
| author_facet | Claudio Marasca Angelo Ruggiero Gabriella Fabbrocini Matteo Megna |
| author_sort | Claudio Marasca |
| collection | DOAJ |
| description | Eosinophilic pustular folliculitis (EPF) (Ofuji disease) is a chronic, noninfectious pruritic cutaneous disorder of unknown etiology. No official guidelines are available for its treatment. Herein we present the case of a 59-year-old Caucasian man admitted to our outpatient clinic due to a generalized itchy skin rash characterized by papulo-pustules involving the face, trunk, and limbs. Histological examination supported the clinical diagnosis of EPF (Ofuji disease). The combination of low-dose oral indomethacin and topical tacrolimus ointment once a day led to a complete resolution of the lesions as well as associated symptoms in 8 weeks. |
| first_indexed | 2024-12-23T20:03:37Z |
| format | Article |
| id | doaj.art-ce0f82acbe8e4e51af525adb7e0a3c20 |
| institution | Directory Open Access Journal |
| issn | 1662-6567 |
| language | English |
| last_indexed | 2024-12-23T20:03:37Z |
| publishDate | 2020-08-01 |
| publisher | Karger Publishers |
| record_format | Article |
| series | Case Reports in Dermatology |
| spelling | doaj.art-ce0f82acbe8e4e51af525adb7e0a3c202022-12-21T17:33:00ZengKarger PublishersCase Reports in Dermatology1662-65672020-08-0112215515810.1159/000509176509176A Case of Ofuji Disease Successfully Treated with the Combination of Low-Dose Indomethacin and Topical TacrolimusClaudio MarascaAngelo RuggieroGabriella FabbrociniMatteo MegnaEosinophilic pustular folliculitis (EPF) (Ofuji disease) is a chronic, noninfectious pruritic cutaneous disorder of unknown etiology. No official guidelines are available for its treatment. Herein we present the case of a 59-year-old Caucasian man admitted to our outpatient clinic due to a generalized itchy skin rash characterized by papulo-pustules involving the face, trunk, and limbs. Histological examination supported the clinical diagnosis of EPF (Ofuji disease). The combination of low-dose oral indomethacin and topical tacrolimus ointment once a day led to a complete resolution of the lesions as well as associated symptoms in 8 weeks.https://www.karger.com/Article/FullText/509176ofuji diseaseeosinophilic pustular folliculitisindomethacintacrolimus |
| spellingShingle | Claudio Marasca Angelo Ruggiero Gabriella Fabbrocini Matteo Megna A Case of Ofuji Disease Successfully Treated with the Combination of Low-Dose Indomethacin and Topical Tacrolimus Case Reports in Dermatology ofuji disease eosinophilic pustular folliculitis indomethacin tacrolimus |
| title | A Case of Ofuji Disease Successfully Treated with the Combination of Low-Dose Indomethacin and Topical Tacrolimus |
| title_full | A Case of Ofuji Disease Successfully Treated with the Combination of Low-Dose Indomethacin and Topical Tacrolimus |
| title_fullStr | A Case of Ofuji Disease Successfully Treated with the Combination of Low-Dose Indomethacin and Topical Tacrolimus |
| title_full_unstemmed | A Case of Ofuji Disease Successfully Treated with the Combination of Low-Dose Indomethacin and Topical Tacrolimus |
| title_short | A Case of Ofuji Disease Successfully Treated with the Combination of Low-Dose Indomethacin and Topical Tacrolimus |
| title_sort | case of ofuji disease successfully treated with the combination of low dose indomethacin and topical tacrolimus |
| topic | ofuji disease eosinophilic pustular folliculitis indomethacin tacrolimus |
| url | https://www.karger.com/Article/FullText/509176 |
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