Reduction of spleen size in a child with Hyperreactive Malarious Splenomegaly (HMS) treated outside the Brazilian endemic area of malaria with only one course of quinine
We report the clinical picture, treatment and evolution of a child with hyperreactive malarious splenomegaly treated outside the endemic area of malaria. The patient presented gross splenomegaly, proceeded from an area where malaria is endemic, showed increased immunoglobulins levels, high antimalar...
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| Format: | Article |
| Language: | English |
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Sociedade Brasileira de Medicina Tropical (SBMT)
1992-12-01
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| Series: | Revista da Sociedade Brasileira de Medicina Tropical |
| Subjects: | |
| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86821992000400008 |
| _version_ | 1811257831234469888 |
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| author | Maria Imaculada Muniz-Junqueira Mário A. P. Moraes Philip Davis Marsden |
| author_facet | Maria Imaculada Muniz-Junqueira Mário A. P. Moraes Philip Davis Marsden |
| author_sort | Maria Imaculada Muniz-Junqueira |
| collection | DOAJ |
| description | We report the clinical picture, treatment and evolution of a child with hyperreactive malarious splenomegaly treated outside the endemic area of malaria. The patient presented gross splenomegaly, proceeded from an area where malaria is endemic, showed increased immunoglobulins levels, high antimalarial antibody titres and hepatic sinusoidal lymphocytosis. The child did not return to an area where malaria is endemic and showed a favorable response to only one course of quinine. The response of this patient to limited antimalarial therapy suggests the importance of reinfection with malaria in the development and maintenance of this syndrome.<br>Relatamos o caso clínico, tratamento e evolução de uma criança com a síndrome da esplenomegalia hiperreativa da malária tratada fora da área endêmica para a malária. A criança apresentava importante esplenomegalia, era procedente de área endêmica para malária, os níveis de imunoglobulinas e de anticorpos antimaláricos estavam elevados e observou-se linfocitose sinusoidal hepática. A criança não voltaria mais para a área endêmica de malária, pelo que foi tratada com apenas um curso de quinino apresentando resposta clínica favorável. Esta resposta a um único curso de terapia curativa antimalárica sugere a importância da reinfecção com o parasitada malária no desenvolvimento e na manutenção desta síndrome. |
| first_indexed | 2024-04-12T18:03:39Z |
| format | Article |
| id | doaj.art-ce12728aab3b4aa78c5c3ea069f8aef0 |
| institution | Directory Open Access Journal |
| issn | 0037-8682 1678-9849 |
| language | English |
| last_indexed | 2024-04-12T18:03:39Z |
| publishDate | 1992-12-01 |
| publisher | Sociedade Brasileira de Medicina Tropical (SBMT) |
| record_format | Article |
| series | Revista da Sociedade Brasileira de Medicina Tropical |
| spelling | doaj.art-ce12728aab3b4aa78c5c3ea069f8aef02022-12-22T03:22:04ZengSociedade Brasileira de Medicina Tropical (SBMT)Revista da Sociedade Brasileira de Medicina Tropical0037-86821678-98491992-12-01254257259Reduction of spleen size in a child with Hyperreactive Malarious Splenomegaly (HMS) treated outside the Brazilian endemic area of malaria with only one course of quinineMaria Imaculada Muniz-JunqueiraMário A. P. MoraesPhilip Davis MarsdenWe report the clinical picture, treatment and evolution of a child with hyperreactive malarious splenomegaly treated outside the endemic area of malaria. The patient presented gross splenomegaly, proceeded from an area where malaria is endemic, showed increased immunoglobulins levels, high antimalarial antibody titres and hepatic sinusoidal lymphocytosis. The child did not return to an area where malaria is endemic and showed a favorable response to only one course of quinine. The response of this patient to limited antimalarial therapy suggests the importance of reinfection with malaria in the development and maintenance of this syndrome.<br>Relatamos o caso clínico, tratamento e evolução de uma criança com a síndrome da esplenomegalia hiperreativa da malária tratada fora da área endêmica para a malária. A criança apresentava importante esplenomegalia, era procedente de área endêmica para malária, os níveis de imunoglobulinas e de anticorpos antimaláricos estavam elevados e observou-se linfocitose sinusoidal hepática. A criança não voltaria mais para a área endêmica de malária, pelo que foi tratada com apenas um curso de quinino apresentando resposta clínica favorável. Esta resposta a um único curso de terapia curativa antimalárica sugere a importância da reinfecção com o parasitada malária no desenvolvimento e na manutenção desta síndrome.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86821992000400008Esplenomegalia hiperreativa da maláriaMalária crônicaTratamento curativo antimaláricoHyperreactive malarious splenomegaly (HMS)Chronic malariaShort antimalarial therapy |
| spellingShingle | Maria Imaculada Muniz-Junqueira Mário A. P. Moraes Philip Davis Marsden Reduction of spleen size in a child with Hyperreactive Malarious Splenomegaly (HMS) treated outside the Brazilian endemic area of malaria with only one course of quinine Revista da Sociedade Brasileira de Medicina Tropical Esplenomegalia hiperreativa da malária Malária crônica Tratamento curativo antimalárico Hyperreactive malarious splenomegaly (HMS) Chronic malaria Short antimalarial therapy |
| title | Reduction of spleen size in a child with Hyperreactive Malarious Splenomegaly (HMS) treated outside the Brazilian endemic area of malaria with only one course of quinine |
| title_full | Reduction of spleen size in a child with Hyperreactive Malarious Splenomegaly (HMS) treated outside the Brazilian endemic area of malaria with only one course of quinine |
| title_fullStr | Reduction of spleen size in a child with Hyperreactive Malarious Splenomegaly (HMS) treated outside the Brazilian endemic area of malaria with only one course of quinine |
| title_full_unstemmed | Reduction of spleen size in a child with Hyperreactive Malarious Splenomegaly (HMS) treated outside the Brazilian endemic area of malaria with only one course of quinine |
| title_short | Reduction of spleen size in a child with Hyperreactive Malarious Splenomegaly (HMS) treated outside the Brazilian endemic area of malaria with only one course of quinine |
| title_sort | reduction of spleen size in a child with hyperreactive malarious splenomegaly hms treated outside the brazilian endemic area of malaria with only one course of quinine |
| topic | Esplenomegalia hiperreativa da malária Malária crônica Tratamento curativo antimalárico Hyperreactive malarious splenomegaly (HMS) Chronic malaria Short antimalarial therapy |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86821992000400008 |
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