Effect of a progesterone-releasing intravaginal device (PRID) for 8 days during a modified Ovsynch protocol on pregnancy outcomes in lactating Holstein cows
Our objective was to evaluate the effect of a progesterone-releasing intravaginal device (PRID) in a 7-d Ovsynch protocol on pregnancy per artificial insemination (P/AI) and pregnancy loss, compared with a standard 7-d Ovsynch protocol without progesterone supplementation. We hypothesized that proge...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2023-07-01
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| Series: | JDS Communications |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S266691022300025X |
| _version_ | 1827901621096415232 |
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| author | M. Hölper L. Bretzinger F. Randi W. Heuwieser S. Borchardt |
| author_facet | M. Hölper L. Bretzinger F. Randi W. Heuwieser S. Borchardt |
| author_sort | M. Hölper |
| collection | DOAJ |
| description | Our objective was to evaluate the effect of a progesterone-releasing intravaginal device (PRID) in a 7-d Ovsynch protocol on pregnancy per artificial insemination (P/AI) and pregnancy loss, compared with a standard 7-d Ovsynch protocol without progesterone supplementation. We hypothesized that progesterone supplementation during an Ovsynch protocol would increase P/AI and decrease pregnancy loss. Data were collected on lactating Holstein cows (n = 716) that either received a 7-d Ovsynch protocol (control: d 0, 100 µg of GnRH; d 7, 500 µg of cloprostenol; d 9, µg of GnRH; n = 360) or a modified Ovsynch protocol with addition of a PRID (PRIDsynch; d 0, 100 µg of GnRH + PRID; d 7, 25 mg of dinoprost; d 8, PRID removal; d 9, 100 µg of GnRH; n = 356). All cows received timed artificial insemination (TAI) approximately 16 h after the second GnRH treatment. Pregnancy diagnosis was performed via ultrasonography on d 38 ± 3 after TAI and rechecked on d 80 ± 7 after TAI. Reproductive performance differed between treatments, with PRIDsynch cows having greater (38.9%) P/AI compared with control cows (31.7%) at d 38 ± 3 and also at d 80 ± 7 (34.6% vs. 28.9%, for PRIDsynch and control cows, respectively). Pregnancy loss did not differ among treatments. |
| first_indexed | 2024-03-12T23:47:48Z |
| format | Article |
| id | doaj.art-ce141af76d7347b496b2ec64c932d15c |
| institution | Directory Open Access Journal |
| issn | 2666-9102 |
| language | English |
| last_indexed | 2024-03-12T23:47:48Z |
| publishDate | 2023-07-01 |
| publisher | Elsevier |
| record_format | Article |
| series | JDS Communications |
| spelling | doaj.art-ce141af76d7347b496b2ec64c932d15c2023-07-14T04:28:36ZengElsevierJDS Communications2666-91022023-07-0144303307Effect of a progesterone-releasing intravaginal device (PRID) for 8 days during a modified Ovsynch protocol on pregnancy outcomes in lactating Holstein cowsM. Hölper0L. Bretzinger1F. Randi2W. Heuwieser3S. Borchardt4Clinic for Animal Reproduction, Faculty of Veterinary Medicine, Freie Universitaet Berlin, Koenigsweg 65, 14163 Berlin, GermanyClinic for Animal Reproduction, Faculty of Veterinary Medicine, Freie Universitaet Berlin, Koenigsweg 65, 14163 Berlin, GermanyCeva Santé Animale, 33500 Libourne, FranceClinic for Animal Reproduction, Faculty of Veterinary Medicine, Freie Universitaet Berlin, Koenigsweg 65, 14163 Berlin, Germany; Corresponding authorClinic for Animal Reproduction, Faculty of Veterinary Medicine, Freie Universitaet Berlin, Koenigsweg 65, 14163 Berlin, GermanyOur objective was to evaluate the effect of a progesterone-releasing intravaginal device (PRID) in a 7-d Ovsynch protocol on pregnancy per artificial insemination (P/AI) and pregnancy loss, compared with a standard 7-d Ovsynch protocol without progesterone supplementation. We hypothesized that progesterone supplementation during an Ovsynch protocol would increase P/AI and decrease pregnancy loss. Data were collected on lactating Holstein cows (n = 716) that either received a 7-d Ovsynch protocol (control: d 0, 100 µg of GnRH; d 7, 500 µg of cloprostenol; d 9, µg of GnRH; n = 360) or a modified Ovsynch protocol with addition of a PRID (PRIDsynch; d 0, 100 µg of GnRH + PRID; d 7, 25 mg of dinoprost; d 8, PRID removal; d 9, 100 µg of GnRH; n = 356). All cows received timed artificial insemination (TAI) approximately 16 h after the second GnRH treatment. Pregnancy diagnosis was performed via ultrasonography on d 38 ± 3 after TAI and rechecked on d 80 ± 7 after TAI. Reproductive performance differed between treatments, with PRIDsynch cows having greater (38.9%) P/AI compared with control cows (31.7%) at d 38 ± 3 and also at d 80 ± 7 (34.6% vs. 28.9%, for PRIDsynch and control cows, respectively). Pregnancy loss did not differ among treatments.http://www.sciencedirect.com/science/article/pii/S266691022300025X |
| spellingShingle | M. Hölper L. Bretzinger F. Randi W. Heuwieser S. Borchardt Effect of a progesterone-releasing intravaginal device (PRID) for 8 days during a modified Ovsynch protocol on pregnancy outcomes in lactating Holstein cows JDS Communications |
| title | Effect of a progesterone-releasing intravaginal device (PRID) for 8 days during a modified Ovsynch protocol on pregnancy outcomes in lactating Holstein cows |
| title_full | Effect of a progesterone-releasing intravaginal device (PRID) for 8 days during a modified Ovsynch protocol on pregnancy outcomes in lactating Holstein cows |
| title_fullStr | Effect of a progesterone-releasing intravaginal device (PRID) for 8 days during a modified Ovsynch protocol on pregnancy outcomes in lactating Holstein cows |
| title_full_unstemmed | Effect of a progesterone-releasing intravaginal device (PRID) for 8 days during a modified Ovsynch protocol on pregnancy outcomes in lactating Holstein cows |
| title_short | Effect of a progesterone-releasing intravaginal device (PRID) for 8 days during a modified Ovsynch protocol on pregnancy outcomes in lactating Holstein cows |
| title_sort | effect of a progesterone releasing intravaginal device prid for 8 days during a modified ovsynch protocol on pregnancy outcomes in lactating holstein cows |
| url | http://www.sciencedirect.com/science/article/pii/S266691022300025X |
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