Neoadjuvant sintilimab and chemotherapy in patients with resectable esophageal squamous cell carcinoma: A prospective, single-arm, phase 2 trial

Neoadjuvant sintilimab and chemotherapy in patients with resectable esophageal squamous cell carcinoma: A prospective, single-arm, phase 2 trial

BackgroundImmunotherapy (Programmed cell death 1 blockade) has entered the ranks of advanced esophageal cancer first-line treatment; however, little is known about the efficacy of PD-1 inhibitor as neoadjuvant therapy in resectable esophageal squamous cell carcinoma (ESCC). We aim to evaluate the ac...

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Bibliographic Details
Main Authors: Zhi Zhang, Jinjun Ye, Hui Li, Dayong Gu, Mingyu Du, Dashan Ai, Wei Chen, Ying Fang, Xinyu Xu, Chenguang Bai, Kuaile Zhao, Guoren Zhou
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-10-01
Series:Frontiers in Immunology
Subjects:
neoadjuvant
sintilimab and chemotherapy
resectable
esophageal squamous cell carcinoma
prospective
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.1031171/full

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