Prediction of the risk of C5 palsy after posterior laminectomy and fusion with cervical myelopathy using a support vector machine: an analysis of 184 consecutive patients
Abstract Background This study aimed to predict C5 palsy (C5P) after posterior laminectomy and fusion (PLF) with cervical myelopathy (CM) from routinely available variables using a support vector machine (SVM) method. Methods We conducted a retrospective investigation based on 184 consecutive patien...
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| Format: | Article |
| Language: | English |
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BMC
2021-05-01
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| Series: | Journal of Orthopaedic Surgery and Research |
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| Online Access: | https://doi.org/10.1186/s13018-021-02476-5 |
| _version_ | 1828350067878133760 |
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| author | Haosheng Wang Zhi-Ri Tang Wenle Li Tingting Fan Jianwu Zhao Mingyang Kang Rongpeng Dong Yang Qu |
| author_facet | Haosheng Wang Zhi-Ri Tang Wenle Li Tingting Fan Jianwu Zhao Mingyang Kang Rongpeng Dong Yang Qu |
| author_sort | Haosheng Wang |
| collection | DOAJ |
| description | Abstract Background This study aimed to predict C5 palsy (C5P) after posterior laminectomy and fusion (PLF) with cervical myelopathy (CM) from routinely available variables using a support vector machine (SVM) method. Methods We conducted a retrospective investigation based on 184 consecutive patients with CM after PLF, and data were collected from March 2013 to December 2019. Clinical and imaging variables were obtained and imported into univariable and multivariable logistic regression analyses to identify risk factors for C5P. According to published reports and clinical experience, a series of variables was selected to develop an SVM machine learning model to predict C5P. The accuracy (ACC), area under the receiver operating characteristic curve (AUC), and confusion matrices were used to evaluate the performance of the prediction model. Results Among the 184 consecutive patients, C5P occurred in 26 patients (14.13%). Multivariate analyses demonstrated the following 4 independent factors associated with C5P: abnormal electromyogram (odds ratio [OR] = 7.861), JOA recovery rate (OR = 1.412), modified Pavlov ratio (OR = 0.009), and presence of C4–C5 foraminal stenosis (OR = 15.492). The SVM model achieved an area under the receiver operating characteristic curve (AUC) of 0.923 and an ACC of 0.918. Additionally, the confusion matrix showed the classification results of the discriminant analysis. Conclusions The designed SVM model presented satisfactory performance in predicting C5P from routinely available variables. However, future external validation is needed. |
| first_indexed | 2024-04-14T01:20:03Z |
| format | Article |
| id | doaj.art-ce1931f8c3084af59e91ec1a1b7b766e |
| institution | Directory Open Access Journal |
| issn | 1749-799X |
| language | English |
| last_indexed | 2024-04-14T01:20:03Z |
| publishDate | 2021-05-01 |
| publisher | BMC |
| record_format | Article |
| series | Journal of Orthopaedic Surgery and Research |
| spelling | doaj.art-ce1931f8c3084af59e91ec1a1b7b766e2022-12-22T02:20:42ZengBMCJournal of Orthopaedic Surgery and Research1749-799X2021-05-011611910.1186/s13018-021-02476-5Prediction of the risk of C5 palsy after posterior laminectomy and fusion with cervical myelopathy using a support vector machine: an analysis of 184 consecutive patientsHaosheng Wang0Zhi-Ri Tang1Wenle Li2Tingting Fan3Jianwu Zhao4Mingyang Kang5Rongpeng Dong6Yang Qu7Department of Orthopedics, Second Hospital of Jilin UniversitySchool of Microelectronics, Wuhan UniversityGuangxi University of Chinese MedicineDepartment of Endocrinology, Second Hospital of Jilin UniversityDepartment of Orthopedics, Second Hospital of Jilin UniversityDepartment of Orthopedics, Second Hospital of Jilin UniversityDepartment of Orthopedics, Second Hospital of Jilin UniversityDepartment of Orthopedics, Second Hospital of Jilin UniversityAbstract Background This study aimed to predict C5 palsy (C5P) after posterior laminectomy and fusion (PLF) with cervical myelopathy (CM) from routinely available variables using a support vector machine (SVM) method. Methods We conducted a retrospective investigation based on 184 consecutive patients with CM after PLF, and data were collected from March 2013 to December 2019. Clinical and imaging variables were obtained and imported into univariable and multivariable logistic regression analyses to identify risk factors for C5P. According to published reports and clinical experience, a series of variables was selected to develop an SVM machine learning model to predict C5P. The accuracy (ACC), area under the receiver operating characteristic curve (AUC), and confusion matrices were used to evaluate the performance of the prediction model. Results Among the 184 consecutive patients, C5P occurred in 26 patients (14.13%). Multivariate analyses demonstrated the following 4 independent factors associated with C5P: abnormal electromyogram (odds ratio [OR] = 7.861), JOA recovery rate (OR = 1.412), modified Pavlov ratio (OR = 0.009), and presence of C4–C5 foraminal stenosis (OR = 15.492). The SVM model achieved an area under the receiver operating characteristic curve (AUC) of 0.923 and an ACC of 0.918. Additionally, the confusion matrix showed the classification results of the discriminant analysis. Conclusions The designed SVM model presented satisfactory performance in predicting C5P from routinely available variables. However, future external validation is needed.https://doi.org/10.1186/s13018-021-02476-5C5 palsyCervical myelopathyPosterior laminectomy and fusionRisk factorsOutcomesSupport vector machine |
| spellingShingle | Haosheng Wang Zhi-Ri Tang Wenle Li Tingting Fan Jianwu Zhao Mingyang Kang Rongpeng Dong Yang Qu Prediction of the risk of C5 palsy after posterior laminectomy and fusion with cervical myelopathy using a support vector machine: an analysis of 184 consecutive patients Journal of Orthopaedic Surgery and Research C5 palsy Cervical myelopathy Posterior laminectomy and fusion Risk factors Outcomes Support vector machine |
| title | Prediction of the risk of C5 palsy after posterior laminectomy and fusion with cervical myelopathy using a support vector machine: an analysis of 184 consecutive patients |
| title_full | Prediction of the risk of C5 palsy after posterior laminectomy and fusion with cervical myelopathy using a support vector machine: an analysis of 184 consecutive patients |
| title_fullStr | Prediction of the risk of C5 palsy after posterior laminectomy and fusion with cervical myelopathy using a support vector machine: an analysis of 184 consecutive patients |
| title_full_unstemmed | Prediction of the risk of C5 palsy after posterior laminectomy and fusion with cervical myelopathy using a support vector machine: an analysis of 184 consecutive patients |
| title_short | Prediction of the risk of C5 palsy after posterior laminectomy and fusion with cervical myelopathy using a support vector machine: an analysis of 184 consecutive patients |
| title_sort | prediction of the risk of c5 palsy after posterior laminectomy and fusion with cervical myelopathy using a support vector machine an analysis of 184 consecutive patients |
| topic | C5 palsy Cervical myelopathy Posterior laminectomy and fusion Risk factors Outcomes Support vector machine |
| url | https://doi.org/10.1186/s13018-021-02476-5 |
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