Sinonasal NK/T-Cell Lymphoma with Upper Gastrointestinal Bleeding: A Case Report

Natural killer (NK)/T-cell lymphoma is the most common malignant lymphoma among sinonasal lymphomas. Diagnosis is difficult and prognosis is poor. Herein, we report the case of a 22-year-old male patient with sinonasal NK/T-cell lymphoma who first presented with nasal obstruction and left facial swe...

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Main Authors: Kuan-Jung Huang, Ling-Feng Wang, Ka-Wo Lee, Kuen-Yao Ho, Wen-Rei Kuo
Format: Article
Language:English
Published: Wiley 2003-12-01
Series:Kaohsiung Journal of Medical Sciences
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1607551X09705194
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author Kuan-Jung Huang
Ling-Feng Wang
Ka-Wo Lee
Kuen-Yao Ho
Wen-Rei Kuo
author_facet Kuan-Jung Huang
Ling-Feng Wang
Ka-Wo Lee
Kuen-Yao Ho
Wen-Rei Kuo
author_sort Kuan-Jung Huang
collection DOAJ
description Natural killer (NK)/T-cell lymphoma is the most common malignant lymphoma among sinonasal lymphomas. Diagnosis is difficult and prognosis is poor. Herein, we report the case of a 22-year-old male patient with sinonasal NK/T-cell lymphoma who first presented with nasal obstruction and left facial swelling. There was a mushroom-like mass over the hard palate, diffuse mucosal swelling in the left nasal cavity, and left orbital cellulitis. The patient underwent a Caldwell-Luc operation, functional endoscopic sinus surgery, and wide excision of the palate tumor. Pathologic examination of the maxillary sinus, nasal cavity, and palate tumor showed an NK/T-cell lymphoma. Two days after the operation, the patient suddenly had bloody stool and suffered hematemesis. A series of examinations revealed a small intestinal hemorrhage. Emergent exploratory laparotomy showed an ulcerative tumor mass with bleeding over the jejunum. Pathologic examination of the mass showed that it was the same as the sinonasal mass, an NK/T-cell lymphoma. We reviewed previous studies on nasal NK/T-cell lymphoma and found no report discussing patients with NK/T-cell lymphoma of both nasal and non-nasal origins. From this case, we learned that in patients with sinonasal NK/T-cell lymphoma, other sites may be involved.
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spelling doaj.art-ce19bd6eb89543788f62490df006cfc42022-12-22T02:29:06ZengWileyKaohsiung Journal of Medical Sciences1607-551X2003-12-01191263964210.1016/S1607-551X(09)70519-4Sinonasal NK/T-Cell Lymphoma with Upper Gastrointestinal Bleeding: A Case ReportKuan-Jung HuangLing-Feng WangKa-Wo LeeKuen-Yao HoWen-Rei KuoNatural killer (NK)/T-cell lymphoma is the most common malignant lymphoma among sinonasal lymphomas. Diagnosis is difficult and prognosis is poor. Herein, we report the case of a 22-year-old male patient with sinonasal NK/T-cell lymphoma who first presented with nasal obstruction and left facial swelling. There was a mushroom-like mass over the hard palate, diffuse mucosal swelling in the left nasal cavity, and left orbital cellulitis. The patient underwent a Caldwell-Luc operation, functional endoscopic sinus surgery, and wide excision of the palate tumor. Pathologic examination of the maxillary sinus, nasal cavity, and palate tumor showed an NK/T-cell lymphoma. Two days after the operation, the patient suddenly had bloody stool and suffered hematemesis. A series of examinations revealed a small intestinal hemorrhage. Emergent exploratory laparotomy showed an ulcerative tumor mass with bleeding over the jejunum. Pathologic examination of the mass showed that it was the same as the sinonasal mass, an NK/T-cell lymphoma. We reviewed previous studies on nasal NK/T-cell lymphoma and found no report discussing patients with NK/T-cell lymphoma of both nasal and non-nasal origins. From this case, we learned that in patients with sinonasal NK/T-cell lymphoma, other sites may be involved.http://www.sciencedirect.com/science/article/pii/S1607551X09705194jejunumnatural killer cellnosesinusT-cell lymphoma
spellingShingle Kuan-Jung Huang
Ling-Feng Wang
Ka-Wo Lee
Kuen-Yao Ho
Wen-Rei Kuo
Sinonasal NK/T-Cell Lymphoma with Upper Gastrointestinal Bleeding: A Case Report
Kaohsiung Journal of Medical Sciences
jejunum
natural killer cell
nose
sinus
T-cell lymphoma
title Sinonasal NK/T-Cell Lymphoma with Upper Gastrointestinal Bleeding: A Case Report
title_full Sinonasal NK/T-Cell Lymphoma with Upper Gastrointestinal Bleeding: A Case Report
title_fullStr Sinonasal NK/T-Cell Lymphoma with Upper Gastrointestinal Bleeding: A Case Report
title_full_unstemmed Sinonasal NK/T-Cell Lymphoma with Upper Gastrointestinal Bleeding: A Case Report
title_short Sinonasal NK/T-Cell Lymphoma with Upper Gastrointestinal Bleeding: A Case Report
title_sort sinonasal nk t cell lymphoma with upper gastrointestinal bleeding a case report
topic jejunum
natural killer cell
nose
sinus
T-cell lymphoma
url http://www.sciencedirect.com/science/article/pii/S1607551X09705194
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AT lingfengwang sinonasalnktcelllymphomawithuppergastrointestinalbleedingacasereport
AT kawolee sinonasalnktcelllymphomawithuppergastrointestinalbleedingacasereport
AT kuenyaoho sinonasalnktcelllymphomawithuppergastrointestinalbleedingacasereport
AT wenreikuo sinonasalnktcelllymphomawithuppergastrointestinalbleedingacasereport