Fetomaternal outcomes in pregnant women with congenital heart disease: a comparative analysis from an apex institute
Objective With advancements in cardiac surgical interventions during infancy and childhood, the incidence of maternal congenital heart disease (CHD) is increasing. This retrospective study compared fetal and cardiac outcomes in women with and without CHD, along with a sub-analysis between cyanotic v...
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| Format: | Article |
| Language: | English |
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Korean Society of Obstetrics and Gynecology
2024-03-01
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| Series: | Obstetrics & Gynecology Science |
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| Online Access: | http://ogscience.org/upload/pdf/ogs-23264.pdf |
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| author | Soniya Dhiman Aparna Sharma Akanksha Gupta Richa Vatsa Juhi Bharti Vidushi Kulshrestha Satyavir Yadav Vatsla Dadhwal Neena Malhotra |
| author_facet | Soniya Dhiman Aparna Sharma Akanksha Gupta Richa Vatsa Juhi Bharti Vidushi Kulshrestha Satyavir Yadav Vatsla Dadhwal Neena Malhotra |
| author_sort | Soniya Dhiman |
| collection | DOAJ |
| description | Objective With advancements in cardiac surgical interventions during infancy and childhood, the incidence of maternal congenital heart disease (CHD) is increasing. This retrospective study compared fetal and cardiac outcomes in women with and without CHD, along with a sub-analysis between cyanotic versus non-cyanotic defects and operated versus non-operated cases. Methods A 10-year data were retrospectively collected from pregnant women with CHD and a 1:1 ratio of pregnant women without any heart disease. Adverse fetal and cardiac outcomes were noted in both groups. Statistical significance was set at P<0.05. Results A total of 86 pregnant women with CHD were studied, with atrial septal defects (29.06%) being the most common. Out of 86 participants, 27 (31.39%) had cyanotic CHD. Around 55% of cases were already operated on for their cardiac defects. Among cardiovascular complications, 5.8% suffered from heart failure, 7.0% had pulmonary arterial hypertension, 8.1% presented in New York Heart Association functional class IV, 9.3% had a need for intensive care unit admission, and one experienced maternal mortality. Adverse fetal outcomes, including operative vaginal delivery, mean duration of hospital stay, fetal growth restriction, preterm birth (<37 weeks), low birth weight (<2,500 g), 5-minute APGAR score <7, and neonatal intensive care unit admissions, were significantly higher in women with CHD than in women without heart disease. Conclusion Women with CHD have a higher risk of adverse fetal and cardiac outcomes. The outcome can be improved with proper pre-conceptional optimization of the cardiac condition, good antenatal care, and multidisciplinary team management. |
| first_indexed | 2024-04-24T23:49:07Z |
| format | Article |
| id | doaj.art-ce1a0c6fc03a43ad93b10e0b7eadf8f3 |
| institution | Directory Open Access Journal |
| issn | 2287-8572 2287-8580 |
| language | English |
| last_indexed | 2024-04-24T23:49:07Z |
| publishDate | 2024-03-01 |
| publisher | Korean Society of Obstetrics and Gynecology |
| record_format | Article |
| series | Obstetrics & Gynecology Science |
| spelling | doaj.art-ce1a0c6fc03a43ad93b10e0b7eadf8f32024-03-15T02:07:37ZengKorean Society of Obstetrics and GynecologyObstetrics & Gynecology Science2287-85722287-85802024-03-0167221822610.5468/ogs.232648808Fetomaternal outcomes in pregnant women with congenital heart disease: a comparative analysis from an apex instituteSoniya Dhiman0Aparna Sharma1Akanksha Gupta2Richa Vatsa3Juhi Bharti4Vidushi Kulshrestha5Satyavir Yadav6Vatsla Dadhwal7Neena Malhotra8 Department of Obstetrics and Gynaecology, All India Institute of Medical Science, New Delhi, India Department of Obstetrics and Gynaecology, All India Institute of Medical Science, New Delhi, India Department of Obstetrics and Gynaecology, All India Institute of Medical Science, New Delhi, India Department of Obstetrics and Gynaecology, All India Institute of Medical Science, New Delhi, India Department of Obstetrics and Gynaecology, All India Institute of Medical Science, New Delhi, India Department of Obstetrics and Gynaecology, All India Institute of Medical Science, New Delhi, India Department of Cardiology, All India Institute of Medical Science, New Delhi, India Department of Obstetrics and Gynaecology, All India Institute of Medical Science, New Delhi, India Department of Obstetrics and Gynaecology, All India Institute of Medical Science, New Delhi, IndiaObjective With advancements in cardiac surgical interventions during infancy and childhood, the incidence of maternal congenital heart disease (CHD) is increasing. This retrospective study compared fetal and cardiac outcomes in women with and without CHD, along with a sub-analysis between cyanotic versus non-cyanotic defects and operated versus non-operated cases. Methods A 10-year data were retrospectively collected from pregnant women with CHD and a 1:1 ratio of pregnant women without any heart disease. Adverse fetal and cardiac outcomes were noted in both groups. Statistical significance was set at P<0.05. Results A total of 86 pregnant women with CHD were studied, with atrial septal defects (29.06%) being the most common. Out of 86 participants, 27 (31.39%) had cyanotic CHD. Around 55% of cases were already operated on for their cardiac defects. Among cardiovascular complications, 5.8% suffered from heart failure, 7.0% had pulmonary arterial hypertension, 8.1% presented in New York Heart Association functional class IV, 9.3% had a need for intensive care unit admission, and one experienced maternal mortality. Adverse fetal outcomes, including operative vaginal delivery, mean duration of hospital stay, fetal growth restriction, preterm birth (<37 weeks), low birth weight (<2,500 g), 5-minute APGAR score <7, and neonatal intensive care unit admissions, were significantly higher in women with CHD than in women without heart disease. Conclusion Women with CHD have a higher risk of adverse fetal and cardiac outcomes. The outcome can be improved with proper pre-conceptional optimization of the cardiac condition, good antenatal care, and multidisciplinary team management.http://ogscience.org/upload/pdf/ogs-23264.pdfcardio-vascular diseaseintrauterine growth restrictionhigh-risk pregnancypremature birthpreconception care |
| spellingShingle | Soniya Dhiman Aparna Sharma Akanksha Gupta Richa Vatsa Juhi Bharti Vidushi Kulshrestha Satyavir Yadav Vatsla Dadhwal Neena Malhotra Fetomaternal outcomes in pregnant women with congenital heart disease: a comparative analysis from an apex institute Obstetrics & Gynecology Science cardio-vascular disease intrauterine growth restriction high-risk pregnancy premature birth preconception care |
| title | Fetomaternal outcomes in pregnant women with congenital heart disease: a comparative analysis from an apex institute |
| title_full | Fetomaternal outcomes in pregnant women with congenital heart disease: a comparative analysis from an apex institute |
| title_fullStr | Fetomaternal outcomes in pregnant women with congenital heart disease: a comparative analysis from an apex institute |
| title_full_unstemmed | Fetomaternal outcomes in pregnant women with congenital heart disease: a comparative analysis from an apex institute |
| title_short | Fetomaternal outcomes in pregnant women with congenital heart disease: a comparative analysis from an apex institute |
| title_sort | fetomaternal outcomes in pregnant women with congenital heart disease a comparative analysis from an apex institute |
| topic | cardio-vascular disease intrauterine growth restriction high-risk pregnancy premature birth preconception care |
| url | http://ogscience.org/upload/pdf/ogs-23264.pdf |
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