ZFP36L2 suppresses mTORc1 through a P53-dependent pathway to prevent peripartum cardiomyopathy in mice
Pregnancy is associated with substantial physiological changes of the heart, and disruptions in these processes can lead to peripartum cardiomyopathy (PPCM). The molecular processes that cause physiological and pathological changes in the heart during pregnancy are not well characterized. Here, we s...
Main Authors: | Hidemichi Kouzu, Yuki Tatekoshi, Hsiang-Chun Chang, Jason S. Shapiro, Warren A. McGee, Adam De Jesus, Issam Ben-Sahra, Zoltan Arany, Jonathan Leor, Chunlei Chen, Perry J. Blackshear, Hossein Ardehali |
---|---|
Format: | Article |
Language: | English |
Published: |
American Society for Clinical Investigation
2022-05-01
|
Series: | The Journal of Clinical Investigation |
Subjects: | |
Online Access: | https://doi.org/10.1172/JCI154491 |
Similar Items
-
ZFP36L2 Role in Thyroid Functionality
by: Francesco Albano, et al.
Published: (2021-08-01) -
A practical approach to cardiovascular medicine /
by: Ardehali, Reza, et al.
Published: (2011) -
Dopamine neuron morphology and output are differentially controlled by mTORC1 and mTORC2
by: Polina Kosillo, et al.
Published: (2022-07-01) -
mTORC1 and mTORC2 differentially promote natural killer cell development
by: Chao Yang, et al.
Published: (2018-05-01) -
The mRNA-binding Protein TTP/ZFP36 in Hepatocarcinogenesis and Hepatocellular Carcinoma
by: Tarek Kröhler, et al.
Published: (2019-11-01)