Serum antioxidant status in Iraqi women with endometrial cancer
Background: Endometrial cancer is the most common gynecologic malignancy in the United States and the fourth most common cancer in women, comprising 6% of female cancers. Objectives: The aim of this study is to investigate the antioxidant vitamins, Coenzyme Q10 and oxidative stress in patients with...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
College of Medicine University of Baghdad
2016-01-01
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| Series: | مجلة كلية الطب |
| Subjects: | |
| Online Access: | http://iqjmc.uobaghdad.edu.iq/index.php/19JFacMedBaghdad36/article/view/289 |
| Summary: | Background: Endometrial cancer is the most common gynecologic malignancy in the United States and the fourth most common cancer in women, comprising 6% of female cancers.
Objectives: The aim of this study is to investigate the antioxidant vitamins, Coenzyme Q10 and oxidative stress in patients with endometrial cancer.
Patients and methods: Fifty six endometrial cancer women patients with various clinical stages (stage 1A, stage1B, stage II, stage III, stage IV) mean aged 58.055 ± 10.561 years, and 30 healthy women volunteers mean aged 39.731 ± 13.504 years, were includes as control group.
Results: The results in this study revealed a highly significant decreased (P<0.01) in β- carotene, Vitamin E and significant increased (P<0.01) in (Uric acid and MDA). The results of ( Coenzyme Q10 and Vitamins (A, C) showed a significant decreased (P<0.05), in the sera levels of patients with endometrial cancer as compared to control group.
Conclusions: This study suggest that high levels of oxidative stress and low levels of antioxidant defense system may be associated with increased the risks of endometrial cancer. |
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| ISSN: | 0041-9419 2410-8057 |