Serum antioxidant status in Iraqi women with endometrial cancer
Background: Endometrial cancer is the most common gynecologic malignancy in the United States and the fourth most common cancer in women, comprising 6% of female cancers. Objectives: The aim of this study is to investigate the antioxidant vitamins, Coenzyme Q10 and oxidative stress in patients with...
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| Format: | Article |
| Language: | English |
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College of Medicine University of Baghdad
2016-01-01
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| Series: | مجلة كلية الطب |
| Subjects: | |
| Online Access: | http://iqjmc.uobaghdad.edu.iq/index.php/19JFacMedBaghdad36/article/view/289 |
| _version_ | 1797369617418551296 |
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| author | Salwa H. N. Al- Ruba,ei Rana K. Jasim Khudhair J. S. Al-Rawaq |
| author_facet | Salwa H. N. Al- Ruba,ei Rana K. Jasim Khudhair J. S. Al-Rawaq |
| author_sort | Salwa H. N. Al- Ruba,ei |
| collection | DOAJ |
| description | Background: Endometrial cancer is the most common gynecologic malignancy in the United States and the fourth most common cancer in women, comprising 6% of female cancers.
Objectives: The aim of this study is to investigate the antioxidant vitamins, Coenzyme Q10 and oxidative stress in patients with endometrial cancer.
Patients and methods: Fifty six endometrial cancer women patients with various clinical stages (stage 1A, stage1B, stage II, stage III, stage IV) mean aged 58.055 ± 10.561 years, and 30 healthy women volunteers mean aged 39.731 ± 13.504 years, were includes as control group.
Results: The results in this study revealed a highly significant decreased (P<0.01) in β- carotene, Vitamin E and significant increased (P<0.01) in (Uric acid and MDA). The results of ( Coenzyme Q10 and Vitamins (A, C) showed a significant decreased (P<0.05), in the sera levels of patients with endometrial cancer as compared to control group.
Conclusions: This study suggest that high levels of oxidative stress and low levels of antioxidant defense system may be associated with increased the risks of endometrial cancer. |
| first_indexed | 2024-03-08T17:49:30Z |
| format | Article |
| id | doaj.art-ce2600b3cb1644238199aaa2d8374cde |
| institution | Directory Open Access Journal |
| issn | 0041-9419 2410-8057 |
| language | English |
| last_indexed | 2024-03-08T17:49:30Z |
| publishDate | 2016-01-01 |
| publisher | College of Medicine University of Baghdad |
| record_format | Article |
| series | مجلة كلية الطب |
| spelling | doaj.art-ce2600b3cb1644238199aaa2d8374cde2024-01-02T09:21:30ZengCollege of Medicine University of Baghdadمجلة كلية الطب0041-94192410-80572016-01-0158410.32007/jfacmedbagdad.v4378-383%Serum antioxidant status in Iraqi women with endometrial cancerSalwa H. N. Al- Ruba,ei0Rana K. Jasim1Khudhair J. S. Al-Rawaq2Dept. of Chemistry, College of Science, Al-Mustansiriya University.Dept. of Chemistry, College of Science, Al-Mustansiriya UniversityDept . of Surgery, College of Medicine, Baghdad UniversityBackground: Endometrial cancer is the most common gynecologic malignancy in the United States and the fourth most common cancer in women, comprising 6% of female cancers. Objectives: The aim of this study is to investigate the antioxidant vitamins, Coenzyme Q10 and oxidative stress in patients with endometrial cancer. Patients and methods: Fifty six endometrial cancer women patients with various clinical stages (stage 1A, stage1B, stage II, stage III, stage IV) mean aged 58.055 ± 10.561 years, and 30 healthy women volunteers mean aged 39.731 ± 13.504 years, were includes as control group. Results: The results in this study revealed a highly significant decreased (P<0.01) in β- carotene, Vitamin E and significant increased (P<0.01) in (Uric acid and MDA). The results of ( Coenzyme Q10 and Vitamins (A, C) showed a significant decreased (P<0.05), in the sera levels of patients with endometrial cancer as compared to control group. Conclusions: This study suggest that high levels of oxidative stress and low levels of antioxidant defense system may be associated with increased the risks of endometrial cancer.http://iqjmc.uobaghdad.edu.iq/index.php/19JFacMedBaghdad36/article/view/289Endometrial cancer, Vitamin A, Vitamin C, Vitamin E, β-carotene, Uric acid, MDA and Coenzyme Q10. |
| spellingShingle | Salwa H. N. Al- Ruba,ei Rana K. Jasim Khudhair J. S. Al-Rawaq Serum antioxidant status in Iraqi women with endometrial cancer مجلة كلية الطب Endometrial cancer, Vitamin A, Vitamin C, Vitamin E, β-carotene, Uric acid, MDA and Coenzyme Q10. |
| title | Serum antioxidant status in Iraqi women with endometrial cancer |
| title_full | Serum antioxidant status in Iraqi women with endometrial cancer |
| title_fullStr | Serum antioxidant status in Iraqi women with endometrial cancer |
| title_full_unstemmed | Serum antioxidant status in Iraqi women with endometrial cancer |
| title_short | Serum antioxidant status in Iraqi women with endometrial cancer |
| title_sort | serum antioxidant status in iraqi women with endometrial cancer |
| topic | Endometrial cancer, Vitamin A, Vitamin C, Vitamin E, β-carotene, Uric acid, MDA and Coenzyme Q10. |
| url | http://iqjmc.uobaghdad.edu.iq/index.php/19JFacMedBaghdad36/article/view/289 |
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