Targeting the NTSR2/TrkB oncogenic pathway in chronic lymphocytic leukemia
Abstract Current therapies that target the B-cell receptor pathway or the inhibition of anti-apoptotic proteins do not prevent the progressive forms of chronic lymphocytic leukemia (CLL), have low long-term efficacy and are subject to therapeutic resistance. Deciphering the mechanisms of leukemic ce...
Main Authors: | Léa Ikhlef, May Yassine, Boutaîna Chandouri, Léa Rivière, Thomas Naves, Natalya Dmytruk, Nathalie Gachard, Marie-Odile Jauberteau, Paul-François Gallet |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2024-03-01
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Series: | Scientific Reports |
Online Access: | https://doi.org/10.1038/s41598-024-56663-5 |
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