Diagnostic Accuracy of Ultrasonography for Detection of Intussusception in Children; a Systematic Review and Meta-Analysis
Introduction: The diagnosis of intussusception can be challenging in children due to the fact that the findings of clinical evaluations are nonspecific and most of the patients present with unclear history. Therefore, in this systematic review and meta-analysis, we aimed to investigate the diagnost...
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| Format: | Article |
| Language: | English |
| Published: |
Shahid Beheshti University of Medical Sciences
2023-02-01
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| Series: | Archives of Academic Emergency Medicine |
| Subjects: | |
| Online Access: | https://journals.sbmu.ac.ir/aaem/index.php/AAEM/article/view/1914 |
| _version_ | 1811162304621838336 |
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| author | Erfan Rahmani Reza Amani-Beni Yasaman Hekmatnia Amirhossein Fakhre Yaseri Seyed-Amirabbas Ahadiat Parham Talebi Boroujeni Moein Kiani Reza Tavakoli Seyyed-Ghavam Shafagh Matin Shirazinia Setareh Garousi Mehran Mottahedi Mohammad Reza Arzaghi Sasan Pourbagher Benam Amir Rigi Amir Salmani Zeynab Abdollahi Fateme Karimzade Rokni Tara Nikbakht Saeme Azizi Hassan Abadi Roozbeh Roohinezhad Forough Masheghati Yas Haririan Bahar Darouei Ehsan Fayyazishishavan Niusha Manoochehri-Arash Mehrdad Farrokhi |
| author_facet | Erfan Rahmani Reza Amani-Beni Yasaman Hekmatnia Amirhossein Fakhre Yaseri Seyed-Amirabbas Ahadiat Parham Talebi Boroujeni Moein Kiani Reza Tavakoli Seyyed-Ghavam Shafagh Matin Shirazinia Setareh Garousi Mehran Mottahedi Mohammad Reza Arzaghi Sasan Pourbagher Benam Amir Rigi Amir Salmani Zeynab Abdollahi Fateme Karimzade Rokni Tara Nikbakht Saeme Azizi Hassan Abadi Roozbeh Roohinezhad Forough Masheghati Yas Haririan Bahar Darouei Ehsan Fayyazishishavan Niusha Manoochehri-Arash Mehrdad Farrokhi |
| author_sort | Erfan Rahmani |
| collection | DOAJ |
| description |
Introduction: The diagnosis of intussusception can be challenging in children due to the fact that the findings of clinical evaluations are nonspecific and most of the patients present with unclear history. Therefore, in this systematic review and meta-analysis, we aimed to investigate the diagnostic accuracy of ultrasonography for detection of intussusception and also compare the efficacy of point-of-care ultrasound (POCUS) with radiologist-performed ultrasound (RADUS).
Methods: Two independent reviewers systematically searched different online electronic databases including MEDLINE, Scopus, Web of Science, Google Scholar, Embase, and Cochrane from inception to December 1, 2022 to identify published papers reporting accuracy of ultrasonography for diagnosis of intussusception. The quality assessment of the included studies was investigated using the Quality Assessment of Diagnostic Accuracy Studies (QUADAS)-2 tool.
Results: A total of 1446 records were retrieved in the initial search of databases. After screening the titles, a total of 344 studies were retrieved for the detailed assessment of full-text. Finally, 37 studies were included in qualitative and quantitative analysis. The pooled sensitivity and specificity of ultrasonography for diagnosis of intussusception were 0.96 (95% CI: 0.95-0.97) and 0.97 (95% CI: 0.97-0.98), respectively. The pooled positive likelihood ratio (PLR) and negative likelihood ratio (NLR) were 24.57 (95% CI: 8.26-73.03) and 0.05 (95% CI: 0.04-0.08), respectively. The area under the hierarchical summary receiver operating characteristic (HSROC) curve was 0.989. Mete-regression showed that there is no significant difference between diagnostic performance of POCUS and RADUS (p = 0.06 and rDOR (diagnostic odds ratio) = 4.38 (95% CI: 0.92-20.89)).
Conclusion: This meta-analysis shows that ultrasonography has excellent sensitivity, specificity, and accuracy for diagnosis of intussusception in pediatric patients. Moreover, we found that diagnostic performance of POCUS is similar to that of RADUS for diagnosis of intussusception.
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| first_indexed | 2024-04-10T06:28:55Z |
| format | Article |
| id | doaj.art-ce288f8593fe45b69bdc90c1337fd67a |
| institution | Directory Open Access Journal |
| issn | 2645-4904 |
| language | English |
| last_indexed | 2024-04-10T06:28:55Z |
| publishDate | 2023-02-01 |
| publisher | Shahid Beheshti University of Medical Sciences |
| record_format | Article |
| series | Archives of Academic Emergency Medicine |
| spelling | doaj.art-ce288f8593fe45b69bdc90c1337fd67a2023-03-01T18:24:36ZengShahid Beheshti University of Medical SciencesArchives of Academic Emergency Medicine2645-49042023-02-0111110.22037/aaem.v11i1.1914Diagnostic Accuracy of Ultrasonography for Detection of Intussusception in Children; a Systematic Review and Meta-AnalysisErfan RahmaniReza Amani-BeniYasaman HekmatniaAmirhossein Fakhre YaseriSeyed-Amirabbas AhadiatParham Talebi BoroujeniMoein KianiReza TavakoliSeyyed-Ghavam ShafaghMatin ShiraziniaSetareh GarousiMehran MottahediMohammad Reza ArzaghiSasan Pourbagher BenamAmir RigiAmir SalmaniZeynab AbdollahiFateme Karimzade RokniTara NikbakhtSaeme Azizi Hassan AbadiRoozbeh RoohinezhadForough MasheghatiYas HaririanBahar DaroueiEhsan FayyazishishavanNiusha Manoochehri-ArashMehrdad Farrokhi Introduction: The diagnosis of intussusception can be challenging in children due to the fact that the findings of clinical evaluations are nonspecific and most of the patients present with unclear history. Therefore, in this systematic review and meta-analysis, we aimed to investigate the diagnostic accuracy of ultrasonography for detection of intussusception and also compare the efficacy of point-of-care ultrasound (POCUS) with radiologist-performed ultrasound (RADUS). Methods: Two independent reviewers systematically searched different online electronic databases including MEDLINE, Scopus, Web of Science, Google Scholar, Embase, and Cochrane from inception to December 1, 2022 to identify published papers reporting accuracy of ultrasonography for diagnosis of intussusception. The quality assessment of the included studies was investigated using the Quality Assessment of Diagnostic Accuracy Studies (QUADAS)-2 tool. Results: A total of 1446 records were retrieved in the initial search of databases. After screening the titles, a total of 344 studies were retrieved for the detailed assessment of full-text. Finally, 37 studies were included in qualitative and quantitative analysis. The pooled sensitivity and specificity of ultrasonography for diagnosis of intussusception were 0.96 (95% CI: 0.95-0.97) and 0.97 (95% CI: 0.97-0.98), respectively. The pooled positive likelihood ratio (PLR) and negative likelihood ratio (NLR) were 24.57 (95% CI: 8.26-73.03) and 0.05 (95% CI: 0.04-0.08), respectively. The area under the hierarchical summary receiver operating characteristic (HSROC) curve was 0.989. Mete-regression showed that there is no significant difference between diagnostic performance of POCUS and RADUS (p = 0.06 and rDOR (diagnostic odds ratio) = 4.38 (95% CI: 0.92-20.89)). Conclusion: This meta-analysis shows that ultrasonography has excellent sensitivity, specificity, and accuracy for diagnosis of intussusception in pediatric patients. Moreover, we found that diagnostic performance of POCUS is similar to that of RADUS for diagnosis of intussusception. https://journals.sbmu.ac.ir/aaem/index.php/AAEM/article/view/1914IntussusceptionUltrasonographyDiagnostic AccuracyMeta-analysisPoint-of-Care TestingDiagnostic Imaging |
| spellingShingle | Erfan Rahmani Reza Amani-Beni Yasaman Hekmatnia Amirhossein Fakhre Yaseri Seyed-Amirabbas Ahadiat Parham Talebi Boroujeni Moein Kiani Reza Tavakoli Seyyed-Ghavam Shafagh Matin Shirazinia Setareh Garousi Mehran Mottahedi Mohammad Reza Arzaghi Sasan Pourbagher Benam Amir Rigi Amir Salmani Zeynab Abdollahi Fateme Karimzade Rokni Tara Nikbakht Saeme Azizi Hassan Abadi Roozbeh Roohinezhad Forough Masheghati Yas Haririan Bahar Darouei Ehsan Fayyazishishavan Niusha Manoochehri-Arash Mehrdad Farrokhi Diagnostic Accuracy of Ultrasonography for Detection of Intussusception in Children; a Systematic Review and Meta-Analysis Archives of Academic Emergency Medicine Intussusception Ultrasonography Diagnostic Accuracy Meta-analysis Point-of-Care Testing Diagnostic Imaging |
| title | Diagnostic Accuracy of Ultrasonography for Detection of Intussusception in Children; a Systematic Review and Meta-Analysis |
| title_full | Diagnostic Accuracy of Ultrasonography for Detection of Intussusception in Children; a Systematic Review and Meta-Analysis |
| title_fullStr | Diagnostic Accuracy of Ultrasonography for Detection of Intussusception in Children; a Systematic Review and Meta-Analysis |
| title_full_unstemmed | Diagnostic Accuracy of Ultrasonography for Detection of Intussusception in Children; a Systematic Review and Meta-Analysis |
| title_short | Diagnostic Accuracy of Ultrasonography for Detection of Intussusception in Children; a Systematic Review and Meta-Analysis |
| title_sort | diagnostic accuracy of ultrasonography for detection of intussusception in children a systematic review and meta analysis |
| topic | Intussusception Ultrasonography Diagnostic Accuracy Meta-analysis Point-of-Care Testing Diagnostic Imaging |
| url | https://journals.sbmu.ac.ir/aaem/index.php/AAEM/article/view/1914 |
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