DNA Sensors with Diamond as a Promising Alternative Transducer Material

Bio-electronics is a scientific field coupling the achievements in biology with electronics to obtain higher sensitivity, specificity and speed. Biosensors have played a pivotal role, and many have become established in the clinical and scientific world. They need to be sensitive, specific, fast and...

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Main Authors: Luc Michiels, Patrick Wagner, Veronique Vermeeren, Sylvia Wenmackers
Format: Article
Language:English
Published: MDPI AG 2009-07-01
Series:Sensors
Subjects:
Online Access:http://www.mdpi.com/1424-8220/9/7/5600/
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author Luc Michiels
Patrick Wagner
Veronique Vermeeren
Sylvia Wenmackers
author_facet Luc Michiels
Patrick Wagner
Veronique Vermeeren
Sylvia Wenmackers
author_sort Luc Michiels
collection DOAJ
description Bio-electronics is a scientific field coupling the achievements in biology with electronics to obtain higher sensitivity, specificity and speed. Biosensors have played a pivotal role, and many have become established in the clinical and scientific world. They need to be sensitive, specific, fast and cheap. Electrochemical biosensors are most frequently cited in literature, often in the context of DNA sensing and mutation analysis. However, many popular electrochemical transduction materials, such as silicon, are susceptible to hydrolysis, leading to loss of bioreceptor molecules from the surface. Hence, increased attention has been shifted towards diamond, which surpasses silicon on many levels.
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spelling doaj.art-ce28b0b179b64c1baac6f8e453b9a9eb2022-12-22T02:57:43ZengMDPI AGSensors1424-82202009-07-01975600563610.3390/s90705600DNA Sensors with Diamond as a Promising Alternative Transducer MaterialLuc MichielsPatrick WagnerVeronique VermeerenSylvia WenmackersBio-electronics is a scientific field coupling the achievements in biology with electronics to obtain higher sensitivity, specificity and speed. Biosensors have played a pivotal role, and many have become established in the clinical and scientific world. They need to be sensitive, specific, fast and cheap. Electrochemical biosensors are most frequently cited in literature, often in the context of DNA sensing and mutation analysis. However, many popular electrochemical transduction materials, such as silicon, are susceptible to hydrolysis, leading to loss of bioreceptor molecules from the surface. Hence, increased attention has been shifted towards diamond, which surpasses silicon on many levels.http://www.mdpi.com/1424-8220/9/7/5600/DNAsingle nucleotide mismatchaptamersbioconjugatesbiosensorsimpedance sensorsSPRfluorescence sensors
spellingShingle Luc Michiels
Patrick Wagner
Veronique Vermeeren
Sylvia Wenmackers
DNA Sensors with Diamond as a Promising Alternative Transducer Material
Sensors
DNA
single nucleotide mismatch
aptamers
bioconjugates
biosensors
impedance sensors
SPR
fluorescence sensors
title DNA Sensors with Diamond as a Promising Alternative Transducer Material
title_full DNA Sensors with Diamond as a Promising Alternative Transducer Material
title_fullStr DNA Sensors with Diamond as a Promising Alternative Transducer Material
title_full_unstemmed DNA Sensors with Diamond as a Promising Alternative Transducer Material
title_short DNA Sensors with Diamond as a Promising Alternative Transducer Material
title_sort dna sensors with diamond as a promising alternative transducer material
topic DNA
single nucleotide mismatch
aptamers
bioconjugates
biosensors
impedance sensors
SPR
fluorescence sensors
url http://www.mdpi.com/1424-8220/9/7/5600/
work_keys_str_mv AT lucmichiels dnasensorswithdiamondasapromisingalternativetransducermaterial
AT patrickwagner dnasensorswithdiamondasapromisingalternativetransducermaterial
AT veroniquevermeeren dnasensorswithdiamondasapromisingalternativetransducermaterial
AT sylviawenmackers dnasensorswithdiamondasapromisingalternativetransducermaterial