DNA Sensors with Diamond as a Promising Alternative Transducer Material
Bio-electronics is a scientific field coupling the achievements in biology with electronics to obtain higher sensitivity, specificity and speed. Biosensors have played a pivotal role, and many have become established in the clinical and scientific world. They need to be sensitive, specific, fast and...
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Format: | Article |
Language: | English |
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MDPI AG
2009-07-01
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Series: | Sensors |
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Online Access: | http://www.mdpi.com/1424-8220/9/7/5600/ |
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author | Luc Michiels Patrick Wagner Veronique Vermeeren Sylvia Wenmackers |
author_facet | Luc Michiels Patrick Wagner Veronique Vermeeren Sylvia Wenmackers |
author_sort | Luc Michiels |
collection | DOAJ |
description | Bio-electronics is a scientific field coupling the achievements in biology with electronics to obtain higher sensitivity, specificity and speed. Biosensors have played a pivotal role, and many have become established in the clinical and scientific world. They need to be sensitive, specific, fast and cheap. Electrochemical biosensors are most frequently cited in literature, often in the context of DNA sensing and mutation analysis. However, many popular electrochemical transduction materials, such as silicon, are susceptible to hydrolysis, leading to loss of bioreceptor molecules from the surface. Hence, increased attention has been shifted towards diamond, which surpasses silicon on many levels. |
first_indexed | 2024-04-13T06:41:29Z |
format | Article |
id | doaj.art-ce28b0b179b64c1baac6f8e453b9a9eb |
institution | Directory Open Access Journal |
issn | 1424-8220 |
language | English |
last_indexed | 2024-04-13T06:41:29Z |
publishDate | 2009-07-01 |
publisher | MDPI AG |
record_format | Article |
series | Sensors |
spelling | doaj.art-ce28b0b179b64c1baac6f8e453b9a9eb2022-12-22T02:57:43ZengMDPI AGSensors1424-82202009-07-01975600563610.3390/s90705600DNA Sensors with Diamond as a Promising Alternative Transducer MaterialLuc MichielsPatrick WagnerVeronique VermeerenSylvia WenmackersBio-electronics is a scientific field coupling the achievements in biology with electronics to obtain higher sensitivity, specificity and speed. Biosensors have played a pivotal role, and many have become established in the clinical and scientific world. They need to be sensitive, specific, fast and cheap. Electrochemical biosensors are most frequently cited in literature, often in the context of DNA sensing and mutation analysis. However, many popular electrochemical transduction materials, such as silicon, are susceptible to hydrolysis, leading to loss of bioreceptor molecules from the surface. Hence, increased attention has been shifted towards diamond, which surpasses silicon on many levels.http://www.mdpi.com/1424-8220/9/7/5600/DNAsingle nucleotide mismatchaptamersbioconjugatesbiosensorsimpedance sensorsSPRfluorescence sensors |
spellingShingle | Luc Michiels Patrick Wagner Veronique Vermeeren Sylvia Wenmackers DNA Sensors with Diamond as a Promising Alternative Transducer Material Sensors DNA single nucleotide mismatch aptamers bioconjugates biosensors impedance sensors SPR fluorescence sensors |
title | DNA Sensors with Diamond as a Promising Alternative Transducer Material |
title_full | DNA Sensors with Diamond as a Promising Alternative Transducer Material |
title_fullStr | DNA Sensors with Diamond as a Promising Alternative Transducer Material |
title_full_unstemmed | DNA Sensors with Diamond as a Promising Alternative Transducer Material |
title_short | DNA Sensors with Diamond as a Promising Alternative Transducer Material |
title_sort | dna sensors with diamond as a promising alternative transducer material |
topic | DNA single nucleotide mismatch aptamers bioconjugates biosensors impedance sensors SPR fluorescence sensors |
url | http://www.mdpi.com/1424-8220/9/7/5600/ |
work_keys_str_mv | AT lucmichiels dnasensorswithdiamondasapromisingalternativetransducermaterial AT patrickwagner dnasensorswithdiamondasapromisingalternativetransducermaterial AT veroniquevermeeren dnasensorswithdiamondasapromisingalternativetransducermaterial AT sylviawenmackers dnasensorswithdiamondasapromisingalternativetransducermaterial |