Anti-quorum sensing activity of poly-amidoamine dendrimer generation 5 dendrimer loaded kinase inhibitor peptide against methicillin-resistant Staphylococcus aureus

Anti-quorum sensing activity of poly-amidoamine dendrimer generation 5 dendrimer loaded kinase inhibitor peptide against methicillin-resistant Staphylococcus aureus

Methicillin-resistant Staphylococcus aureus (MRSA) is a significant concern in both healthcare and community settings, as it causes numerous infections worldwide with high morbidity and mortality rates. One promising strategy is to target the quorum sensing (QS) system of MRSA using a dendrimer load...

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Bibliographic Details
Main Authors: Naifa A. Alenazi, Fadilah S. Aleanizy, Fulwah Y. Alqahtani, Abdullah A. Aldossari, Mohammed M. Alanazi, Rihaf Alfaraj
Format: Article
Language:English
Published: Elsevier 2024-02-01
Series:Saudi Pharmaceutical Journal
Subjects:
Methicillin-resistant Staphylococcus aureus
poly-amidoamine dendrimers (PAMAM)
Anti-virulence agent
Accessory gene regulator
Histidine kinase inhibitor
Online Access:http://www.sciencedirect.com/science/article/pii/S1319016423004279

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http://www.sciencedirect.com/science/article/pii/S1319016423004279

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