Study of Helicobacter Pylori Antibody Serum Level in Patients with Migraine Headache
Introduction & Objective: Mechanisms underlying migraine precipitation are largely unknown. Helicobacter pylori (H. pylori) infection has recently been associated with various extraintestinal pathologies and migraine. The relation between Helicobacter pylori and Migraine is controversial. The ai...
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Format: | Article |
Language: | fas |
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Hamadan University of Medical Sciences
2013-03-01
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Series: | پزشکی بالینی ابن سینا |
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Online Access: | http://sjh.umsha.ac.ir/article-1-165-en.html |
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author | Shahir Mazaheri Esmaeil Eslami |
author_facet | Shahir Mazaheri Esmaeil Eslami |
author_sort | Shahir Mazaheri |
collection | DOAJ |
description | Introduction & Objective: Mechanisms underlying migraine precipitation are largely unknown. Helicobacter pylori (H. pylori) infection has recently been associated with various extraintestinal pathologies and migraine. The relation between Helicobacter pylori and Migraine is controversial. The aim of this study was to investigate the correlation of the H. pylori infection with migraine. Materials & Methods: In a case-control study, a total of 80 patients with migraine with aura and without aura who came to neurology clinic of ّFarshchian hospital affiliated with Hamedan Medical University were enrolled in the study and compared with a group of 80 controls. The patients with the history of anti h. pylori medication, chronic inflammatory diseases and malignancy were excluded. Helicobacter pylori infection was diagnosed by ELISA test for IgG. The diagnosis and classification of migraine were made according to the International Headache Society (IHS) criteria. The serum level of IgG was compared in each group by student t test.Results: The mean age in migraine and control groups were 27.26±8.99 and 29.04±9.75 years respectively. The serum level of anti-Helicobacter pylori IgG were 39.75±45.09 and 24.93±27.88 Uarb/ml in migraine and control groups respectively (P=0.013). The mean of IgG based on the demographic data were not different in both group (P>0.05). Conclusion: This study demonstrated a higher level of anti-Helicobacter pylori IgG in patients with migraine. |
first_indexed | 2024-12-12T17:16:25Z |
format | Article |
id | doaj.art-ce2e7ffd493447e1851fa327b0e86a25 |
institution | Directory Open Access Journal |
issn | 2588-722X 2588-7238 |
language | fas |
last_indexed | 2024-12-12T17:16:25Z |
publishDate | 2013-03-01 |
publisher | Hamadan University of Medical Sciences |
record_format | Article |
series | پزشکی بالینی ابن سینا |
spelling | doaj.art-ce2e7ffd493447e1851fa327b0e86a252022-12-22T00:17:47ZfasHamadan University of Medical Sciencesپزشکی بالینی ابن سینا2588-722X2588-72382013-03-011945761Study of Helicobacter Pylori Antibody Serum Level in Patients with Migraine HeadacheShahir Mazaheri0Esmaeil Eslami1 Introduction & Objective: Mechanisms underlying migraine precipitation are largely unknown. Helicobacter pylori (H. pylori) infection has recently been associated with various extraintestinal pathologies and migraine. The relation between Helicobacter pylori and Migraine is controversial. The aim of this study was to investigate the correlation of the H. pylori infection with migraine. Materials & Methods: In a case-control study, a total of 80 patients with migraine with aura and without aura who came to neurology clinic of ّFarshchian hospital affiliated with Hamedan Medical University were enrolled in the study and compared with a group of 80 controls. The patients with the history of anti h. pylori medication, chronic inflammatory diseases and malignancy were excluded. Helicobacter pylori infection was diagnosed by ELISA test for IgG. The diagnosis and classification of migraine were made according to the International Headache Society (IHS) criteria. The serum level of IgG was compared in each group by student t test.Results: The mean age in migraine and control groups were 27.26±8.99 and 29.04±9.75 years respectively. The serum level of anti-Helicobacter pylori IgG were 39.75±45.09 and 24.93±27.88 Uarb/ml in migraine and control groups respectively (P=0.013). The mean of IgG based on the demographic data were not different in both group (P>0.05). Conclusion: This study demonstrated a higher level of anti-Helicobacter pylori IgG in patients with migraine.http://sjh.umsha.ac.ir/article-1-165-en.htmlimmunoglobulin ghelicobacter pylorimigraine |
spellingShingle | Shahir Mazaheri Esmaeil Eslami Study of Helicobacter Pylori Antibody Serum Level in Patients with Migraine Headache پزشکی بالینی ابن سینا immunoglobulin g helicobacter pylori migraine |
title | Study of Helicobacter Pylori Antibody Serum Level in Patients with Migraine Headache |
title_full | Study of Helicobacter Pylori Antibody Serum Level in Patients with Migraine Headache |
title_fullStr | Study of Helicobacter Pylori Antibody Serum Level in Patients with Migraine Headache |
title_full_unstemmed | Study of Helicobacter Pylori Antibody Serum Level in Patients with Migraine Headache |
title_short | Study of Helicobacter Pylori Antibody Serum Level in Patients with Migraine Headache |
title_sort | study of helicobacter pylori antibody serum level in patients with migraine headache |
topic | immunoglobulin g helicobacter pylori migraine |
url | http://sjh.umsha.ac.ir/article-1-165-en.html |
work_keys_str_mv | AT shahirmazaheri studyofhelicobacterpyloriantibodyserumlevelinpatientswithmigraineheadache AT esmaeileslami studyofhelicobacterpyloriantibodyserumlevelinpatientswithmigraineheadache |