A Rapid and Sensitive Method to Measure the Functional Activity of Shiga Toxins in Human Serum

A Rapid and Sensitive Method to Measure the Functional Activity of Shiga Toxins in Human Serum

Shiga toxins (Stx) have a definite role in the development of hemolytic uremic syndrome in children with hemorrhagic colitis caused by pathogenic Stx-producing Escherichia coli (STEC) strains. The dramatic effects of these toxins on the microvasculature of different organs, particularly of the kidn...

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Bibliographic Details
Main Authors: Valentina Arfilli, Domenica Carnicelli, Gianluigi Ardissino, Erminio Torresani, Gaia Scavia, Maurizio Brigotti
Format: Article
Language:English
Published: MDPI AG 2015-11-01
Series:Toxins
Subjects:
hemolytic uremic syndrome
Shiga toxin-producing Escherichia coli
eukaryotic protein synthesis
Raji cells
Online Access:http://www.mdpi.com/2072-6651/7/11/4564

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