Recent advances in magnetic nanocarriers for tumor treatment
Magnetic nanocarriers are nano-platforms that integrate multiple moieties based on magnetic nanoparticles for diagnostic and therapeutic purposes. In recent years, they have become an advanced platform for tumor treatment due to their wide application in magnetic resonance imaging (MRI), biocatalysi...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2023-03-01
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| Series: | Biomedicine & Pharmacotherapy |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S075333222300015X |
| _version_ | 1811172230422331392 |
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| author | Jianmeng Zhu Jian Wang Yiping Li |
| author_facet | Jianmeng Zhu Jian Wang Yiping Li |
| author_sort | Jianmeng Zhu |
| collection | DOAJ |
| description | Magnetic nanocarriers are nano-platforms that integrate multiple moieties based on magnetic nanoparticles for diagnostic and therapeutic purposes. In recent years, they have become an advanced platform for tumor treatment due to their wide application in magnetic resonance imaging (MRI), biocatalysis, magneto-thermal therapy (MHT), and photoresponsive therapy. Drugs loaded into magnetic nanocarriers can efficiently be directed to targeted areas by precisely reshaping their structural properties. Magnetic nanocarriers allow us to track the location of the therapeutic agent, continuously control the therapeutic process and eventually assess the efficacy of the treatment. They are typically used in synergistic therapeutic applications to achieve precise and effective tumor treatment. Here we review their latest applications in tumor treatment, including stimuli-responsive drug delivery, MHT, photoresponsive therapy, immunotherapy, gene therapy, and synergistic therapy. We consider reducing toxicity, improving antitumor efficacy, and the targeting accuracy of magnetic nanocarriers. The challenges of their clinical translation and prospects in cancer therapy are also discussed. |
| first_indexed | 2024-04-10T17:27:27Z |
| format | Article |
| id | doaj.art-ce47622d72414a0c8b11e7f464762b93 |
| institution | Directory Open Access Journal |
| issn | 0753-3322 |
| language | English |
| last_indexed | 2024-04-10T17:27:27Z |
| publishDate | 2023-03-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Biomedicine & Pharmacotherapy |
| spelling | doaj.art-ce47622d72414a0c8b11e7f464762b932023-02-04T04:17:00ZengElsevierBiomedicine & Pharmacotherapy0753-33222023-03-01159114227Recent advances in magnetic nanocarriers for tumor treatmentJianmeng Zhu0Jian Wang1Yiping Li2Correspondence to: Clinical Laboratory of Chun'an First People's Hospital, Hangzhou Medical College Affiliated Chun'an Hospital, 1869 Huanhu North Road, Chunan, Hangzhou 311700, Zhejiang, PR China.; Clinical Laboratory of Chun'an First People's Hospital, Zhejiang Provincial People's Hospital Chun'an Branch, Hangzhou Medical College Affiliated Chun'an Hospital, Hangzhou, Zhejiang, PR ChinaClinical Laboratory of Chun'an First People's Hospital, Zhejiang Provincial People's Hospital Chun'an Branch, Hangzhou Medical College Affiliated Chun'an Hospital, Hangzhou, Zhejiang, PR ChinaClinical Laboratory of Chun'an First People's Hospital, Zhejiang Provincial People's Hospital Chun'an Branch, Hangzhou Medical College Affiliated Chun'an Hospital, Hangzhou, Zhejiang, PR ChinaMagnetic nanocarriers are nano-platforms that integrate multiple moieties based on magnetic nanoparticles for diagnostic and therapeutic purposes. In recent years, they have become an advanced platform for tumor treatment due to their wide application in magnetic resonance imaging (MRI), biocatalysis, magneto-thermal therapy (MHT), and photoresponsive therapy. Drugs loaded into magnetic nanocarriers can efficiently be directed to targeted areas by precisely reshaping their structural properties. Magnetic nanocarriers allow us to track the location of the therapeutic agent, continuously control the therapeutic process and eventually assess the efficacy of the treatment. They are typically used in synergistic therapeutic applications to achieve precise and effective tumor treatment. Here we review their latest applications in tumor treatment, including stimuli-responsive drug delivery, MHT, photoresponsive therapy, immunotherapy, gene therapy, and synergistic therapy. We consider reducing toxicity, improving antitumor efficacy, and the targeting accuracy of magnetic nanocarriers. The challenges of their clinical translation and prospects in cancer therapy are also discussed.http://www.sciencedirect.com/science/article/pii/S075333222300015XMagnetic nanocarriersTumor treatmentDrug deliverySynergistic therapy |
| spellingShingle | Jianmeng Zhu Jian Wang Yiping Li Recent advances in magnetic nanocarriers for tumor treatment Biomedicine & Pharmacotherapy Magnetic nanocarriers Tumor treatment Drug delivery Synergistic therapy |
| title | Recent advances in magnetic nanocarriers for tumor treatment |
| title_full | Recent advances in magnetic nanocarriers for tumor treatment |
| title_fullStr | Recent advances in magnetic nanocarriers for tumor treatment |
| title_full_unstemmed | Recent advances in magnetic nanocarriers for tumor treatment |
| title_short | Recent advances in magnetic nanocarriers for tumor treatment |
| title_sort | recent advances in magnetic nanocarriers for tumor treatment |
| topic | Magnetic nanocarriers Tumor treatment Drug delivery Synergistic therapy |
| url | http://www.sciencedirect.com/science/article/pii/S075333222300015X |
| work_keys_str_mv | AT jianmengzhu recentadvancesinmagneticnanocarriersfortumortreatment AT jianwang recentadvancesinmagneticnanocarriersfortumortreatment AT yipingli recentadvancesinmagneticnanocarriersfortumortreatment |