A Conserved Tryptophan in the Envelope Cytoplasmic Tail Regulates HIV-1 Assembly and Spread

A Conserved Tryptophan in the Envelope Cytoplasmic Tail Regulates HIV-1 Assembly and Spread

The HIV-1 envelope (Env) is an essential determinant of viral infectivity, tropism and spread between T cells. Lentiviral Env contain an unusually long 150 amino acid cytoplasmic tail (EnvCT), but the function of the EnvCT and many conserved domains within it remain largely uncharacterised. Here, we...

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Bibliographic Details
Main Authors: Xenia Snetkov, Tafhima Haider, Dejan Mesner, Nicholas Groves, Schuyler B. van Engelenburg, Clare Jolly
Format: Article
Language:English
Published: MDPI AG 2022-01-01
Series:Viruses
Subjects:
HIV-1
Env
viral assembly
cell–cell
T cell
Online Access:https://www.mdpi.com/1999-4915/14/1/129

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