Helicobacter pylori infection and its associated factors among dyspepsia patients attending Debre Tabor Comprehensive Specialized Hospital, 2020
<h4>Introduction</h4> Helicobacter pylori is one of the most common bacterial infections of humankind that affects more than 50% of the world’s population. It has been implicated as an important agent in the pathogenesis of peptic ulcer disease and gastric cancer. Data regarding its prev...
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| Format: | Article |
| Language: | English |
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Public Library of Science (PLoS)
2023-01-01
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| Series: | PLoS ONE |
| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9997881/?tool=EBI |
| _version_ | 1811154286153826304 |
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| author | Tadeg Jemere Mekdes Tilahun Gashaw Walle Getachew Yideg Assefa Agegnehu Anemut Tilahun Edget Abebe Natnael Moges |
| author_facet | Tadeg Jemere Mekdes Tilahun Gashaw Walle Getachew Yideg Assefa Agegnehu Anemut Tilahun Edget Abebe Natnael Moges |
| author_sort | Tadeg Jemere |
| collection | DOAJ |
| description | <h4>Introduction</h4> Helicobacter pylori is one of the most common bacterial infections of humankind that affects more than 50% of the world’s population. It has been implicated as an important agent in the pathogenesis of peptic ulcer disease and gastric cancer. Data regarding its prevalence using stool antigen test is scarce in Ethiopia. Hence, the main aim of this study is to determine the prevalence of Helicobacter pylori infection among dyspeptic patients using stool antigen test and assessing the potential risk factors. <h4>Methods</h4> Institution based cross-sectional study was conducted on 373 dyspepsia patients. Data were collected using a pre-tested interviewer administered questionnaire. SPSS Version 23 for Windows software was used for summarization and analyses of data. Bivariate analysis was conducted to detect the association between dependent and independent variables, and all candidate variables were entered into multivariate logistic regression. Statistical significance was set at p-value <0.05. <h4>Result</h4> More than one-third (34%) of dyspepsia patients were positive for H. pylori stool antigen test. Having greater than or equal to four children in the house [AOR = 7.5 95% CI (1.7, 33.6) p = 0.008)], absence of latrine for the house hold [AOR = 4.3 95% CI (1, 17.8), p = 0.043 and drinking of river water [AOR = 12.5 95% CI (1.5, 105), p = 0.021] were predictors of H-pylori infection. <h4>Conclusion</h4> More than one-third of dyspepsia patients were positive for H-pylori infection. Overcrowding and poor hygienic conditions are the main risk factors of H-pylori infection. |
| first_indexed | 2024-04-10T04:14:13Z |
| format | Article |
| id | doaj.art-ce48a742ebed457cbc612a8ac4521513 |
| institution | Directory Open Access Journal |
| issn | 1932-6203 |
| language | English |
| last_indexed | 2024-04-10T04:14:13Z |
| publishDate | 2023-01-01 |
| publisher | Public Library of Science (PLoS) |
| record_format | Article |
| series | PLoS ONE |
| spelling | doaj.art-ce48a742ebed457cbc612a8ac45215132023-03-12T05:32:31ZengPublic Library of Science (PLoS)PLoS ONE1932-62032023-01-01183Helicobacter pylori infection and its associated factors among dyspepsia patients attending Debre Tabor Comprehensive Specialized Hospital, 2020Tadeg JemereMekdes TilahunGashaw WalleGetachew YidegAssefa AgegnehuAnemut TilahunEdget AbebeNatnael Moges<h4>Introduction</h4> Helicobacter pylori is one of the most common bacterial infections of humankind that affects more than 50% of the world’s population. It has been implicated as an important agent in the pathogenesis of peptic ulcer disease and gastric cancer. Data regarding its prevalence using stool antigen test is scarce in Ethiopia. Hence, the main aim of this study is to determine the prevalence of Helicobacter pylori infection among dyspeptic patients using stool antigen test and assessing the potential risk factors. <h4>Methods</h4> Institution based cross-sectional study was conducted on 373 dyspepsia patients. Data were collected using a pre-tested interviewer administered questionnaire. SPSS Version 23 for Windows software was used for summarization and analyses of data. Bivariate analysis was conducted to detect the association between dependent and independent variables, and all candidate variables were entered into multivariate logistic regression. Statistical significance was set at p-value <0.05. <h4>Result</h4> More than one-third (34%) of dyspepsia patients were positive for H. pylori stool antigen test. Having greater than or equal to four children in the house [AOR = 7.5 95% CI (1.7, 33.6) p = 0.008)], absence of latrine for the house hold [AOR = 4.3 95% CI (1, 17.8), p = 0.043 and drinking of river water [AOR = 12.5 95% CI (1.5, 105), p = 0.021] were predictors of H-pylori infection. <h4>Conclusion</h4> More than one-third of dyspepsia patients were positive for H-pylori infection. Overcrowding and poor hygienic conditions are the main risk factors of H-pylori infection.https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9997881/?tool=EBI |
| spellingShingle | Tadeg Jemere Mekdes Tilahun Gashaw Walle Getachew Yideg Assefa Agegnehu Anemut Tilahun Edget Abebe Natnael Moges Helicobacter pylori infection and its associated factors among dyspepsia patients attending Debre Tabor Comprehensive Specialized Hospital, 2020 PLoS ONE |
| title | Helicobacter pylori infection and its associated factors among dyspepsia patients attending Debre Tabor Comprehensive Specialized Hospital, 2020 |
| title_full | Helicobacter pylori infection and its associated factors among dyspepsia patients attending Debre Tabor Comprehensive Specialized Hospital, 2020 |
| title_fullStr | Helicobacter pylori infection and its associated factors among dyspepsia patients attending Debre Tabor Comprehensive Specialized Hospital, 2020 |
| title_full_unstemmed | Helicobacter pylori infection and its associated factors among dyspepsia patients attending Debre Tabor Comprehensive Specialized Hospital, 2020 |
| title_short | Helicobacter pylori infection and its associated factors among dyspepsia patients attending Debre Tabor Comprehensive Specialized Hospital, 2020 |
| title_sort | helicobacter pylori infection and its associated factors among dyspepsia patients attending debre tabor comprehensive specialized hospital 2020 |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9997881/?tool=EBI |
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