A 48-Year-Old Male with Cutaneous Metastases of NUT Midline Carcinoma Misdiagnosed as Herpes Zoster
NUT (nuclear protein of the testis) midline carcinoma (NMC) is a rare, poorly differentiated neoplasm with dismal prognosis. Though NMC are often metastatic by the time of presentation, cutaneous metastases have not been well described in the literature. We report a case of NMC in a patient who pres...
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Karger Publishers
2017-11-01
|
| Series: | Case Reports in Oncology |
| Subjects: | |
| Online Access: | https://www.karger.com/Article/FullText/481429 |
| _version_ | 1818452554149789696 |
|---|---|
| author | Lauren N. Ko Qing Y. Weng Johanna S. Song Mackenzie Asel Scott R. Granter Arash Mostaghimi |
| author_facet | Lauren N. Ko Qing Y. Weng Johanna S. Song Mackenzie Asel Scott R. Granter Arash Mostaghimi |
| author_sort | Lauren N. Ko |
| collection | DOAJ |
| description | NUT (nuclear protein of the testis) midline carcinoma (NMC) is a rare, poorly differentiated neoplasm with dismal prognosis. Though NMC are often metastatic by the time of presentation, cutaneous metastases have not been well described in the literature. We report a case of NMC in a patient who presented with grouped well-demarcated tender non-ulcerated erythematous nodules on the right mid-back. The lesions were initially diagnosed and treated as herpes zoster. Following failure to improve with antiviral therapy, imaging and skin biopsy revealed that the lesions were in fact cutaneous NUT carcinoma. Although NMC is an uncommon diagnosis, clinicians should be aware that affected patients can develop skin involvement to avoid unnecessary and harmful treatments. |
| first_indexed | 2024-12-14T21:24:56Z |
| format | Article |
| id | doaj.art-ce5090ec8a98465585c971d1c12ccaf4 |
| institution | Directory Open Access Journal |
| issn | 1662-6575 |
| language | English |
| last_indexed | 2024-12-14T21:24:56Z |
| publishDate | 2017-11-01 |
| publisher | Karger Publishers |
| record_format | Article |
| series | Case Reports in Oncology |
| spelling | doaj.art-ce5090ec8a98465585c971d1c12ccaf42022-12-21T22:46:52ZengKarger PublishersCase Reports in Oncology1662-65752017-11-0110398799110.1159/000481429481429A 48-Year-Old Male with Cutaneous Metastases of NUT Midline Carcinoma Misdiagnosed as Herpes ZosterLauren N. KoQing Y. WengJohanna S. SongMackenzie AselScott R. GranterArash MostaghimiNUT (nuclear protein of the testis) midline carcinoma (NMC) is a rare, poorly differentiated neoplasm with dismal prognosis. Though NMC are often metastatic by the time of presentation, cutaneous metastases have not been well described in the literature. We report a case of NMC in a patient who presented with grouped well-demarcated tender non-ulcerated erythematous nodules on the right mid-back. The lesions were initially diagnosed and treated as herpes zoster. Following failure to improve with antiviral therapy, imaging and skin biopsy revealed that the lesions were in fact cutaneous NUT carcinoma. Although NMC is an uncommon diagnosis, clinicians should be aware that affected patients can develop skin involvement to avoid unnecessary and harmful treatments.https://www.karger.com/Article/FullText/481429NUT carcinomaSkinCutaneous metastases |
| spellingShingle | Lauren N. Ko Qing Y. Weng Johanna S. Song Mackenzie Asel Scott R. Granter Arash Mostaghimi A 48-Year-Old Male with Cutaneous Metastases of NUT Midline Carcinoma Misdiagnosed as Herpes Zoster Case Reports in Oncology NUT carcinoma Skin Cutaneous metastases |
| title | A 48-Year-Old Male with Cutaneous Metastases of NUT Midline Carcinoma Misdiagnosed as Herpes Zoster |
| title_full | A 48-Year-Old Male with Cutaneous Metastases of NUT Midline Carcinoma Misdiagnosed as Herpes Zoster |
| title_fullStr | A 48-Year-Old Male with Cutaneous Metastases of NUT Midline Carcinoma Misdiagnosed as Herpes Zoster |
| title_full_unstemmed | A 48-Year-Old Male with Cutaneous Metastases of NUT Midline Carcinoma Misdiagnosed as Herpes Zoster |
| title_short | A 48-Year-Old Male with Cutaneous Metastases of NUT Midline Carcinoma Misdiagnosed as Herpes Zoster |
| title_sort | 48 year old male with cutaneous metastases of nut midline carcinoma misdiagnosed as herpes zoster |
| topic | NUT carcinoma Skin Cutaneous metastases |
| url | https://www.karger.com/Article/FullText/481429 |
| work_keys_str_mv | AT laurennko a48yearoldmalewithcutaneousmetastasesofnutmidlinecarcinomamisdiagnosedasherpeszoster AT qingyweng a48yearoldmalewithcutaneousmetastasesofnutmidlinecarcinomamisdiagnosedasherpeszoster AT johannassong a48yearoldmalewithcutaneousmetastasesofnutmidlinecarcinomamisdiagnosedasherpeszoster AT mackenzieasel a48yearoldmalewithcutaneousmetastasesofnutmidlinecarcinomamisdiagnosedasherpeszoster AT scottrgranter a48yearoldmalewithcutaneousmetastasesofnutmidlinecarcinomamisdiagnosedasherpeszoster AT arashmostaghimi a48yearoldmalewithcutaneousmetastasesofnutmidlinecarcinomamisdiagnosedasherpeszoster AT laurennko 48yearoldmalewithcutaneousmetastasesofnutmidlinecarcinomamisdiagnosedasherpeszoster AT qingyweng 48yearoldmalewithcutaneousmetastasesofnutmidlinecarcinomamisdiagnosedasherpeszoster AT johannassong 48yearoldmalewithcutaneousmetastasesofnutmidlinecarcinomamisdiagnosedasherpeszoster AT mackenzieasel 48yearoldmalewithcutaneousmetastasesofnutmidlinecarcinomamisdiagnosedasherpeszoster AT scottrgranter 48yearoldmalewithcutaneousmetastasesofnutmidlinecarcinomamisdiagnosedasherpeszoster AT arashmostaghimi 48yearoldmalewithcutaneousmetastasesofnutmidlinecarcinomamisdiagnosedasherpeszoster |