The uPAR System as a Potential Therapeutic Target in the Diseased Eye

The uPAR System as a Potential Therapeutic Target in the Diseased Eye

Dysregulation of vascular networks is characteristic of eye diseases associated with retinal cell degeneration and visual loss. Visual impairment is also the consequence of photoreceptor degeneration in inherited eye diseases with a major inflammatory component, but without angiogenic profile. Among...

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Bibliographic Details
Main Authors: Maurizio Cammalleri, Massimo Dal Monte, Vincenzo Pavone, Mario De Rosa, Dario Rusciano, Paola Bagnoli
Format: Article
Language:English
Published: MDPI AG 2019-08-01
Series:Cells
Subjects:
ocular diseases
animal models
angiogenesis
inflammation
vascular leakage
photoreceptor degeneration
retinal function
co-receptor signaling
uPAR system blockade
Online Access:https://www.mdpi.com/2073-4409/8/8/925

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