Superparamagnetic Fe/Au Nanoparticles and Their Feasibility for Magnetic Hyperthermia
Today, magnetic hyperthermia constitutes a complementary way to cancer treatment. This article reports a promising aspect of magnetic hyperthermia addressing superparamagnetic and highly Fe/Au core-shell nanoparticles. Those nanoparticles were prepared using a wet chemical approach at room temperatu...
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2021-07-01
|
| Series: | Applied Sciences |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2076-3417/11/14/6637 |
| _version_ | 1797527622354206720 |
|---|---|
| author | Mohamed F. Sanad Bianca P. Meneses-Brassea Dawn S. Blazer Shirin Pourmiri George C. Hadjipanayis Ahmed A. El-Gendy |
| author_facet | Mohamed F. Sanad Bianca P. Meneses-Brassea Dawn S. Blazer Shirin Pourmiri George C. Hadjipanayis Ahmed A. El-Gendy |
| author_sort | Mohamed F. Sanad |
| collection | DOAJ |
| description | Today, magnetic hyperthermia constitutes a complementary way to cancer treatment. This article reports a promising aspect of magnetic hyperthermia addressing superparamagnetic and highly Fe/Au core-shell nanoparticles. Those nanoparticles were prepared using a wet chemical approach at room temperature. We found that the as-synthesized core shells assembled with spherical morphology, including face-centered-cubic Fe cores coated and Au shells. The high-resolution transmission microscope images (HRTEM) revealed the formation of Fe/Au core/shell nanoparticles. The magnetic properties of the samples showed hysteresis loops with coercivity (HC) close to zero, revealing superparamagnetic-like behavior at room temperature. The saturation magnetization (MS) has the value of 165 emu/g for the as-synthesized sample with a Fe:Au ratio of 2:1. We also studied the feasibility of those core-shell particles for magnetic hyperthermia using different frequencies and different applied alternating magnetic fields. The Fe/Au core-shell nanoparticles achieved a specific absorption rate of 50 W/g under applied alternating magnetic field with amplitude 400 Oe and 304 kHz frequency. Based on our findings, the samples can be used as a promising candidate for magnetic hyperthermia for cancer therapy. |
| first_indexed | 2024-03-10T09:46:21Z |
| format | Article |
| id | doaj.art-ce56e7401b5f4a9b9eec6d62e66a42b6 |
| institution | Directory Open Access Journal |
| issn | 2076-3417 |
| language | English |
| last_indexed | 2024-03-10T09:46:21Z |
| publishDate | 2021-07-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Applied Sciences |
| spelling | doaj.art-ce56e7401b5f4a9b9eec6d62e66a42b62023-11-22T03:13:09ZengMDPI AGApplied Sciences2076-34172021-07-011114663710.3390/app11146637Superparamagnetic Fe/Au Nanoparticles and Their Feasibility for Magnetic HyperthermiaMohamed F. Sanad0Bianca P. Meneses-Brassea1Dawn S. Blazer2Shirin Pourmiri3George C. Hadjipanayis4Ahmed A. El-Gendy5Department of Physics, University of Texas at El Paso, El Paso, TX 79968, USADepartment of Physics, University of Texas at El Paso, El Paso, TX 79968, USADepartment of Physics, University of Texas at El Paso, El Paso, TX 79968, USADepartment of Physics and Astronomy, University of Delaware, Newark, DE 19716, USADepartment of Physics and Astronomy, University of Delaware, Newark, DE 19716, USADepartment of Physics, University of Texas at El Paso, El Paso, TX 79968, USAToday, magnetic hyperthermia constitutes a complementary way to cancer treatment. This article reports a promising aspect of magnetic hyperthermia addressing superparamagnetic and highly Fe/Au core-shell nanoparticles. Those nanoparticles were prepared using a wet chemical approach at room temperature. We found that the as-synthesized core shells assembled with spherical morphology, including face-centered-cubic Fe cores coated and Au shells. The high-resolution transmission microscope images (HRTEM) revealed the formation of Fe/Au core/shell nanoparticles. The magnetic properties of the samples showed hysteresis loops with coercivity (HC) close to zero, revealing superparamagnetic-like behavior at room temperature. The saturation magnetization (MS) has the value of 165 emu/g for the as-synthesized sample with a Fe:Au ratio of 2:1. We also studied the feasibility of those core-shell particles for magnetic hyperthermia using different frequencies and different applied alternating magnetic fields. The Fe/Au core-shell nanoparticles achieved a specific absorption rate of 50 W/g under applied alternating magnetic field with amplitude 400 Oe and 304 kHz frequency. Based on our findings, the samples can be used as a promising candidate for magnetic hyperthermia for cancer therapy.https://www.mdpi.com/2076-3417/11/14/6637Fe/Au nanoparticlessuperparamagneticcore/shellmagnetic nanoparticle hyperthermia |
| spellingShingle | Mohamed F. Sanad Bianca P. Meneses-Brassea Dawn S. Blazer Shirin Pourmiri George C. Hadjipanayis Ahmed A. El-Gendy Superparamagnetic Fe/Au Nanoparticles and Their Feasibility for Magnetic Hyperthermia Applied Sciences Fe/Au nanoparticles superparamagnetic core/shell magnetic nanoparticle hyperthermia |
| title | Superparamagnetic Fe/Au Nanoparticles and Their Feasibility for Magnetic Hyperthermia |
| title_full | Superparamagnetic Fe/Au Nanoparticles and Their Feasibility for Magnetic Hyperthermia |
| title_fullStr | Superparamagnetic Fe/Au Nanoparticles and Their Feasibility for Magnetic Hyperthermia |
| title_full_unstemmed | Superparamagnetic Fe/Au Nanoparticles and Their Feasibility for Magnetic Hyperthermia |
| title_short | Superparamagnetic Fe/Au Nanoparticles and Their Feasibility for Magnetic Hyperthermia |
| title_sort | superparamagnetic fe au nanoparticles and their feasibility for magnetic hyperthermia |
| topic | Fe/Au nanoparticles superparamagnetic core/shell magnetic nanoparticle hyperthermia |
| url | https://www.mdpi.com/2076-3417/11/14/6637 |
| work_keys_str_mv | AT mohamedfsanad superparamagneticfeaunanoparticlesandtheirfeasibilityformagnetichyperthermia AT biancapmenesesbrassea superparamagneticfeaunanoparticlesandtheirfeasibilityformagnetichyperthermia AT dawnsblazer superparamagneticfeaunanoparticlesandtheirfeasibilityformagnetichyperthermia AT shirinpourmiri superparamagneticfeaunanoparticlesandtheirfeasibilityformagnetichyperthermia AT georgechadjipanayis superparamagneticfeaunanoparticlesandtheirfeasibilityformagnetichyperthermia AT ahmedaelgendy superparamagneticfeaunanoparticlesandtheirfeasibilityformagnetichyperthermia |