On cross-ancestry cancer polygenic risk scores.

Polygenic risk scores (PRS) can provide useful information for personalized risk stratification and disease risk assessment, especially when combined with non-genetic risk factors. However, their construction depends on the availability of summary statistics from genome-wide association studies (GWA...

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Detalhes bibliográficos
Principais autores: Lars G Fritsche, Ying Ma, Daiwei Zhang, Maxwell Salvatore, Seunggeun Lee, Xiang Zhou, Bhramar Mukherjee
Formato: Artigo
Idioma:English
Publicado em: Public Library of Science (PLoS) 2021-09-01
coleção:PLoS Genetics
Acesso em linha:https://doi.org/10.1371/journal.pgen.1009670