Evaluating Nutritional Risk Factors for Delirium in Intensive-Care-Unit Patients: Present Insights and Prospects for Future Research
Malnutrition, hypercatabolism, and metabolic changes are well-established risk factors for delirium in critically ill patients. Although the exact mechanisms are not fully understood, there is mounting evidence suggesting that malnutrition can cause a variety of changes that contribute to delirium,...
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| Format: | Article |
| Language: | English |
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MDPI AG
2023-12-01
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| Series: | Clinics and Practice |
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| Online Access: | https://www.mdpi.com/2039-7283/13/6/138 |
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| author | Arianna Piccirillo Francesco Perri Alessandro Vittori Franco Ionna Francesco Sabbatino Alessandro Ottaiano Marco Cascella |
| author_facet | Arianna Piccirillo Francesco Perri Alessandro Vittori Franco Ionna Francesco Sabbatino Alessandro Ottaiano Marco Cascella |
| author_sort | Arianna Piccirillo |
| collection | DOAJ |
| description | Malnutrition, hypercatabolism, and metabolic changes are well-established risk factors for delirium in critically ill patients. Although the exact mechanisms are not fully understood, there is mounting evidence suggesting that malnutrition can cause a variety of changes that contribute to delirium, such as electrolyte imbalances, immune dysfunction, and alterations in drug metabolism. Therefore, a comprehensive metabolic and malnutrition assessment, along with appropriate nutritional support, may help to prevent or ameliorate malnutrition, reduce hypercatabolism, and improve overall physiological function, ultimately lowering the risk of delirium. For this aim, bioelectrical impedance analysis can represent a valuable strategy. Further research into the underlying mechanisms and nutritional risk factors for delirium is crucial to developing more effective prevention strategies. Understanding these processes will allow clinicians to personalize treatment plans for individual patients, leading to improved outcomes and quality of life in the intensive-care-unit survivors. |
| first_indexed | 2024-03-08T20:54:07Z |
| format | Article |
| id | doaj.art-ce5d638fd0b44ebab104b12cb50bd668 |
| institution | Directory Open Access Journal |
| issn | 2039-7283 |
| language | English |
| last_indexed | 2024-03-08T20:54:07Z |
| publishDate | 2023-12-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Clinics and Practice |
| spelling | doaj.art-ce5d638fd0b44ebab104b12cb50bd6682023-12-22T14:01:01ZengMDPI AGClinics and Practice2039-72832023-12-011361577159210.3390/clinpract13060138Evaluating Nutritional Risk Factors for Delirium in Intensive-Care-Unit Patients: Present Insights and Prospects for Future ResearchArianna Piccirillo0Francesco Perri1Alessandro Vittori2Franco Ionna3Francesco Sabbatino4Alessandro Ottaiano5Marco Cascella6Otolaryngology and Maxillo-Facial Surgery Unit, Istituto Nazionale Tumori—IRCCS Fondazione G. Pascale, 80131 Naples, ItalyMedical and Experimental Head and Neck Oncology Unit, Istituto Nazionale Tumori—IRCCS Fondazione G. Pascale, 80131 Naples, ItalyDepartment of Anesthesia and Critical Care, ARCO ROMA, Ospedale Pediatrico Bambino Gesù IRCCS, Piazza S. Onofrio 4, 00165 Rome, ItalyOtolaryngology and Maxillo-Facial Surgery Unit, Istituto Nazionale Tumori—IRCCS Fondazione G. Pascale, 80131 Naples, ItalyMedical Oncology Department, University of Salerno, 84084 Fisciano, ItalySSD Innovative Therapies for Abdominal Metastases, Abdominal Oncology, Istituto Nazionale Tumori di Napoli, IRCCS “G. Pascale”, 80131 Naples, ItalyUnit of Anesthesiology, Intensive Care Medicine, and Pain Medicine, Department of Medicine, Surgery, and Dentistry, University of Salerno, Via Salvador Allende, 43, 84081 Baronissi, ItalyMalnutrition, hypercatabolism, and metabolic changes are well-established risk factors for delirium in critically ill patients. Although the exact mechanisms are not fully understood, there is mounting evidence suggesting that malnutrition can cause a variety of changes that contribute to delirium, such as electrolyte imbalances, immune dysfunction, and alterations in drug metabolism. Therefore, a comprehensive metabolic and malnutrition assessment, along with appropriate nutritional support, may help to prevent or ameliorate malnutrition, reduce hypercatabolism, and improve overall physiological function, ultimately lowering the risk of delirium. For this aim, bioelectrical impedance analysis can represent a valuable strategy. Further research into the underlying mechanisms and nutritional risk factors for delirium is crucial to developing more effective prevention strategies. Understanding these processes will allow clinicians to personalize treatment plans for individual patients, leading to improved outcomes and quality of life in the intensive-care-unit survivors.https://www.mdpi.com/2039-7283/13/6/138malnutritionintensive care medicinedeliriumhypercatabolismbioelectrical impedance analysis |
| spellingShingle | Arianna Piccirillo Francesco Perri Alessandro Vittori Franco Ionna Francesco Sabbatino Alessandro Ottaiano Marco Cascella Evaluating Nutritional Risk Factors for Delirium in Intensive-Care-Unit Patients: Present Insights and Prospects for Future Research Clinics and Practice malnutrition intensive care medicine delirium hypercatabolism bioelectrical impedance analysis |
| title | Evaluating Nutritional Risk Factors for Delirium in Intensive-Care-Unit Patients: Present Insights and Prospects for Future Research |
| title_full | Evaluating Nutritional Risk Factors for Delirium in Intensive-Care-Unit Patients: Present Insights and Prospects for Future Research |
| title_fullStr | Evaluating Nutritional Risk Factors for Delirium in Intensive-Care-Unit Patients: Present Insights and Prospects for Future Research |
| title_full_unstemmed | Evaluating Nutritional Risk Factors for Delirium in Intensive-Care-Unit Patients: Present Insights and Prospects for Future Research |
| title_short | Evaluating Nutritional Risk Factors for Delirium in Intensive-Care-Unit Patients: Present Insights and Prospects for Future Research |
| title_sort | evaluating nutritional risk factors for delirium in intensive care unit patients present insights and prospects for future research |
| topic | malnutrition intensive care medicine delirium hypercatabolism bioelectrical impedance analysis |
| url | https://www.mdpi.com/2039-7283/13/6/138 |
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